- ISBN: 9781405176637 | 1405176636
- Cover: Paperback
- Copyright: 4/26/2010
John Strang is Professor of the Addictions and Director of the National Addiction Centre, University of London. He is also Clinical Director of the addictions treatment services at the South London & Maudsley NHS Foundation Trust.
Peter M Miller is Professor of the Department of Psychiatry and Behavioral Sciences at the Medical University of South Carolina. He is Editor-in-Chief of the journal, Addictive Behaviors.
List of Contributors | |
Introduction | |
Introduction | |
Where to start? | |
Does theory matter? | |
The literature review | |
Which method suits my question is a screwdriver better than a saw? | |
Focus and structure of the book | |
Terminology | |
The need for a wider perspective and more careful selection of study design | |
Research Fundamentals | |
Reliability and validity | |
Introduction | |
Background: Reliability and validity in addiction research | |
Reliability and validity in addiction research | |
Strengthening the quality of your results and conclusions: A brief checklist to improve reliability and validity | |
Summary | |
Sampling strategies for addiction research | |
Introduction | |
Probability sampling | |
Non-probability sampling | |
Qualitative sampling | |
Selecting your sampling approach | |
Technical considerations | |
Conclusion | |
Experimental design issues in addiction research | |
Introduction | |
What constitutes an experiment? | |
Is an experiment appropriate? | |
What kind of experimental design | |
What intervention and comparison conditions? | |
What target population and recruitment strategy? | |
What sample size? | |
What outcome measures? | |
What statistical analyses? | |
Conclusions | |
Qualitative methods and theory in addictions research | |
Introduction | |
Theory | |
A recurring debate | |
Principles for practice | |
Data generation | |
Analysis | |
Conclusions | |
Ethical issues in alcohol, other drugs and addiction-related research | |
Introduction | |
Key concepts | |
Major ethical frameworks | |
Addiction-specific ethical issues | |
Writing an ethics application | |
Ethical processes in different countries | |
Influence of funding body | |
Ethical dissemination | |
Conclusion | |
Basic Toolbox | |
Surveys and questionnaire design | |
Introduction | |
Brief history | |
Survey research designs | |
Advantages and limitations of survey research designs | |
Modes of data collection | |
Questionnaire design | |
Piloting the questionnaire | |
Technological assistance | |
Common challenges | |
Interviews | |
Introduction | |
Why interviews? | |
Reliability and validity of self-reported information | |
Interviewing skills | |
Types of interviews | |
Types of interview data | |
Technological resources | |
Summary | |
Scales for research in the addictions | |
Introduction | |
Screening instruments | |
Frequency of substance use | |
Multi-dimensional scales | |
Dependence | |
Psychopathology | |
Summary | |
Biomarkers of alcohol and other drug use | |
Introduction | |
Uses of state biomarkers in research | |
General principles when considering biomarkers | |
Summary | |
Quantitative data analysis | |
Introduction | |
Imagining data planning the study | |
Collecting data gathering the measurements | |
Organising data structuring the measurements | |
Describing data what do the data look like? | |
Manipulating data | |
Relationships within the data | |
Interpreting relationships within the data | |
Conclusion and exercises | |
Real World Research Methods | |
Applied research methods | |
Introduction | |
Auditing clinical activity in the city | |
Needs assessment | |
Qualitative research approaches | |
Evaluation research | |
The audit cycle | |
Measuring outcomes in applied settings | |
Overview and conclusions | |
Conducting clinical research | |
Conducting clinical research | |
Discussion and conclusions: The role of the practitioner-researcher | |
Biological Methods | |
Psychopharmacology | |
Introduction | |
Psychopharmacology: drugs, behaviour, physiology and the brain | |
Measuring drug effects | |
Human drug self-administration | |
Drug withdrawal and craving | |
Summary | |
Imaging | |
Introduction | |
Introduction to neuroimaging | |
Imaging techniques 235 | |
Image analysis 241 | |
Some considerations when setting up an imaging study | |
Genes, genetics, genomics and epigenetics | |
Introduction | |
Animal studies | |
Quantitative genetics | |
Molecular genetics | |
Why bother? 263 | |
An addiction gene | |
Ethics | |
Concluding remarks | |
Animal models | |
Introduction | |
Basic principles of behaviour: Reinforcement | |
Basic principles of behaviour: Effects of environmental cues | |
Drug self-administration: Simple schedules | |
Drug self-administration: Using dose-effect curves to assess the effects of treatments | |
Drug self-administration: Measuring the reinforcing effects of drugs | |
Drug self-administration: Modelling the effects of environmental cues with second-order schedules | |
Drug self-administration: Reinstatement | |
Drug self-administration: Modelling the uncontrolled and compulsive nature of addiction | |
Intracranial drug self-administration and intracranial electrical self-stimulation | |
Drug self-administration: Advantages and disadvantages | |
Conditioned place preference | |
Drug discrimination | |
Locomotor activity | |
Adjunct procedures | |
Integration of behavioural and neuroscience techniques | |
Specialist Methods | |
Understanding contexts: Methods and analysis in ethnographic research on drugs | |
Introduction | |
Tracing the history of ethnographic drug research | |
Designing ethnographic research | |
Getting started | |
Collecting data | |
Analysing ethnographic data | |
Producing ethnographic texts | |
Conclusion | |
Epidemiology | |
Introduction | |
Origins of epidemiology | |
Definitions and uses of epidemiology in alcohol and other drug research | |
Descriptive epidemiology | |
Epidemiological research designs | |
Analysis of case-control and cohort studies | |
Experimental study designs | |
Potential sources of error in epidemiology | |
Summary | |
Meta-analysis: Summarising findings on addiction intervention effects | |
Introduction | |
Overview of meta-analytic methods | |
Issues in meta-analyses of addiction interventions | |
Limitations | |
Conclusion | |
Drug trend monitoring | |
Introduction | |
Point of departure divergent policy perspectives, difficulties in definition and temporal relevance | |
International, national and local drug monitoring mechanisms | |
Challenges in monitoring illicit drug use | |
An overview of common information sources and some of their limitations | |
Issues for the interpretation and analysis of data | |
Mixed methods | |
Triangulation | |
Reliability and validity | |
Reflections in a broken mirror: Pragmatic and imperfect solutions to an intractable problem | |
Drug policy research | |
Introduction | |
Methods for quantitatively comparing an interventions benefits and costs | |
Issues that arise in quantifying an interventions benefits and costs | |
Methods for estimating an interventions effects | |
Modelling methods | |
Summary | |
Beyond Research | |
Concluding remarks | |
Publishing addiction science | |
Final thoughts | |
Index | |
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