Agitator Design for Gas-Liquid Fermenters and Bioreactors

Explore the basic principles and concepts of the design of agitation systems for fermenters and bioreactors

Agitator Design for Gas-Liquid Fermenters and Bioreactors delivers a ­concise treatment and explanation of how to design mechanically sound agitation systems that will perform the agitation process function efficiently and economically. The book covers agitator fundamentals, impeller systems, optimum power and air flow at peak mass transfer calculations, optimizing operation for minimum energy per batch, heat transfer surfaces and calculations, shaft seal considerations, mounting methods, mechanical design, and vendor evaluation.

The accomplished author has created a practical and hands-on tool that discusses the subject of agitation systems from first principles all the way to implementation in the real world. Step-by-step processes are included throughout the book to assist engineers, chemists, and other scientists in the design, construction, installation, and maintenance of these systems.

Readers will also benefit from the inclusion of:

Perfect for chemical engineers, mechanical engineers, process engineers, chemists, and materials scientists, Agitator Design for Gas-Liquid Fermenters and Bioreactors will also earn a place in the libraries of pharmaceutical scientists seeking a one-stop resource for designing mechanically sound agitation systems.

Gregory T. Benz, P.E., is the head of Benz Technology International, an engineering consulting firm and Chinese business development corporation. He has authored numerous articles, conducted more than 50 seminars, and holds a patent on a nonrotating, nonseal method of mechanically agitating tanks.

Prelims

Dedication

Foreword

Preface

Chapter 1 Purpose of Agitator Design

Chapter 2 Major Steps in Successful Agitator Design

Chapter 3 Agitator Fundamentals

Chapter 4 Agitator Behavior under Gassed Conditions

Chapter 5 Impeller Types Used in Fermenters

Chapter 6 Impeller Systems

Chapter 7 Piloting for Mass Transfer

Chapter 8 Power and Gas Flow Design and Optimization

Chapter 9 Optimizing Operation for Minimum Energy Consumption per Batch

Chapter 10 Heat Transfer Surfaces and Calculations

Chapter 11 Gasses Other Than Air and Liquids other than Water

Chapter 12 Viscous Fermentation

Chapter 13 Three Phase Fermentation

Chapter 14 Use of CFD in Fermenter Design

Chapter 15 Agitator seal design considerations

Chapter 16 Fermenter Agitator Mounting Methods

Chapter 17 Mechanical Design of Fermenter Agitators

Chapter 18 Sanitary Design

Chapter 19 Aspect Ratio

Chapter 20 Vendor evaluation

Chapter 21 International Practices

Index

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