Alzheimer's: The Latest Assessment and Treatment Strategies
, by Grossberg, George T., M.D.Note: Supplemental materials are not guaranteed with Rental or Used book purchases.
- ISBN: 9780763765798 | 0763765791
- Cover: Paperback
- Copyright: 11/1/2009
In Alzheimer's: The Latest Assessment And Treatment Strategies, experts George T. Grossberg, MD, and Sanjeev M. Kamat, MD, succinctly outline the disease, with key topics that include:
George T. Grossberg, MD, earned his medical degree and was chief resident in the department of psychiatry at Saint Louis University School of Medicine. He is the past president of the American Association for Geriatric Psychiatry and the International Psychogeriatric Association. He is a distinguished fellow in the American Psychiatric Association and has authored or coauthored more than 400 scientific meeting abstracts, book chapters, and journal articles, and edited eight textbooks. His articles have been published in several peer-reviewed journals such as Dementia and Geriatric Cognitive Disorders, Neurology, the American journal of Geriatric Psychiatry, and the journal of the American Medical Association. Dr. Grossberg has received many honors and awards including the first Robert Lerner. MD, Memorial Award for National Contributions to the Field of Geriatrics from the University of Wisconsin. He has been listed as one of the Best Doctors in America since its inception, and has been included in America's Top Doctors since its inception. He was also named one of America's Top 327 Mental Health Experts by Good Housekeeping magazine. Sanjeev M. Kamat, MD, is staff psychiatrist at Saint Alexius Hospital and Forest Park Hospital in St. Louis, MO, and Jefferson Regional Medical Center in Crystal City, MO. He is also a voluntary faculty member at Saint Louis University School of Medicine. Dr. Kamat finished his psychiatry residency and completed his geriatric psychiatry fellowship at Saint Louis University School of Medicine. He has published a number of articles in various peer-reviewed journals, and has also participated in a number of clinical trials.
General Information About Alzheimer's Disease | p. 1 |
What Is Alzheimer's Disease? | p. 2 |
How Does Alzheimer's Disease Affect PatientsĘ Lives? | p. 3 |
Stages of Alzheimer's Disease | p. 3 |
How Common Is Alzheimer's Disease? | p. 5 |
What Are the Risk Factors and Potential Protective Factors in Alzheimer's Disease? | p. 6 |
Risk Factors | p. 6 |
Protective Factors | p. 8 |
Chapter Summary | p. 10 |
Diagnosing and Assessing Alzheimer's Disease | p. 11 |
What Are the Typical Presenting Features in Patients With Alzheimer's Disease? | p. 11 |
Cognition | p. 12 |
Activities of Daily Living | p. 13 |
Behavior | p. 13 |
What Are the Criteria for Diagnosing Alzheimer's Disease? | p. 14 |
What Tools Are Available for Clinical Assessment of Alzheimer's Disease? | p. 18 |
Clinical Interview (Medical and Psychiatric History) | p. 18 |
Laboratory Evaluations | p. 22 |
Radiological Findings | p. 22 |
Genetic Testing | p. 23 |
Neuropsychological Testing | p. 23 |
Diagnostic Workup Summary | p. 27 |
What Differentiates Alzheimer's Disease From Normal Aging and From Other Disorders? | p. 27 |
Normal Aging | p. 27 |
Subjective Cognitive Impairment | p. 27 |
Age-Associated Memory Impairment | p. 29 |
Mild Cognitive Impairment | p. 29 |
Vascular Dementia | p. 29 |
Lewy Body Dementia (LBD) | p. 30 |
Parkinson Disease Dementia (PDD) | p. 30 |
Mixed Dementia | p. 30 |
Frontotemporal Dementia | p. 31 |
Geriatric Depression | p. 31 |
Chapter Summary | p. 31 |
Pharmacotherapy in Alzheimer's Disease | p. 33 |
What are the Neuroanatomical and Neurochemical Hallmarks of Alzheimer's Disease? | p. 34 |
Biochemical Factors Related to Alzheimer's Disease | p. 34 |
Specific Brain Areas Involved in Alzheimer's Disease | p. 34 |
What Medications Are Available for Stabilization or Improvement of Symptoms in Patients With Alzheimer's Disease? | p. 35 |
Cholinesterase Inhibitors (ChEI) | p. 35 |
NMDA Receptor Antagonist: Memantine (Namenda) | p. 38 |
Treatment Recommendations for Patients With Alzheimer's Disease | p. 39 |
Efficacy of Treatment | p. 40 |
What Medications Are Used to Treat BPSD in Patients With Alzheimer's Disease, and What Are Their Efficacies? | p. 45 |
Atypical Antipsychotics | p. 45 |
Typical or Conventional Antipsychotics | p. 47 |
Antidepressant Medications | p. 48 |
Benzodiazepines | p. 48 |
Anticonvulsants | p. 48 |
Cholinesterase Inhibitors | p. 49 |
Memantine | p. 49 |
What Alternative Treatments Can Be Used to Treat Patients With Alzheimer's Disease? | p. 50 |
Estrogen | p. 50 |
Omega-3 Fatty Acids | p. 50 |
Vitamin C and Vitamin E | p. 51 |
Mediterranean Diet | p. 52 |
What Are the Emerging or Disease-Modifying Treatments for Patients With Alzheimer's Disease? | p. 52 |
Anti-Inflammatory Drugs | p. 53 |
Statins | p. 53 |
Amyloid-Modifying Agents | p. 53 |
Immune Therapies | p. 54 |
Neurogenesis Agents | p. 55 |
Methylene Blue | p. 56 |
How Does Comorbidity Affect Pharmacotherapy Choices for Alzheimer's Disease? | p. 56 |
Comorbid Conditions | p. 56 |
Cost of Caring for Alzheimer's Disease Patients With Comorbid Conditions | p. 57 |
How Can Alzheimer's Disease Be Prevented Through Lifestyle Modifications? | p. 58 |
Chapter Summary | p. 59 |
Psychosocial Treatments for Alzheimer's Disease | p. 61 |
What Psychosocial Interventions Are Used to Treat BPSD in Patients With Alzheimer's Disease, and How Effective Are They? | p. 61 |
Depression | p. 62 |
Anxiety | p. 63 |
Wandering | p. 64 |
Apathy | p. 65 |
Agitation | p. 66 |
Psychosis | p. 67 |
Sleep Abnormalities | p. 69 |
What Other Therapeutic Interventions Can Be Tried in Patients With Alzheimer's Disease? | p. 70 |
Reminiscence Therapy | p. 70 |
Validation Therapy | p. 70 |
Reality Orientation | p. 71 |
Chapter Summary | p. 71 |
Ethical, Legal, and Caregiver Issues in Alzheimer's Disease | p. 73 |
What Are the Important End-of-Life Issues in Alzheimer's Disease? | p. 73 |
When to Stop Treatments | p. 73 |
Feeding Issues in Patients With Alzheimer's Disease | p. 74 |
Hospice Care for Patients With Alzheimer's Disease | p. 74 |
What Are the Important Legal Issues Confronting Families of Patients With Alzheimer's Disease? | p. 75 |
Advance Directives | p. 75 |
Guardianship | p. 76 |
What Are the Important Issues for Caregivers of Patients With Alzheimer's Disease? | p. 78 |
Stress | p. 78 |
Role of Caregiver Education in Delaying Institutionalization | p. 79 |
Resources for Caregivers of Patients With Alzheimer's Disease | p. 80 |
What Are the Various Care Options for Patients With Alzheimer's Disease?80 | |
Adult Daycare Centers | p. 80 |
Assisted Living | p. 81 |
Nursing Homes | p. 82 |
Special Care Units | p. 83 |
Chapter Summary | p. 84 |
Appendix: Resources for Caregivers and Physicians | p. 85 |
Resources for Caregivers | p. 85 |
Internet Resources | p. 85 |
Books and Articles | p. 85 |
Internet Resources for Physicians | p. 86 |
Glossary | p. 87 |
References | p. 91 |
Index | p. 105 |
Table of Contents provided by Ingram. All Rights Reserved. |
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