Note: Supplemental materials are not guaranteed with Rental or Used book purchases.
- ISBN: 9780120890309 | 0120890305
- Cover: Paperback
- Copyright: 10/15/1999
Sodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some examples of sodium regulating tissues include kidney, colon, lung, and sweat ducts. Sodium transport across these membranes is a two-step process: entry through an amiloride-sensitive sodium channel and exit via the ouabain-sensitive sodium/potassium ATPase. The sodium entry channels are the rate-limiting determinant for transport and are regulated by several different hormones. The sodium channels also play a significant role in a number of disease states, like hypertension, edema, drug-induced hyperkalemia, and cystic fibrosis. Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity provides the first in-depth exchange of ideas concerning these sodium channels, their regulation and involvement in normal and pathophysiological situations.
Contributors | xv | ||||
Preface | xix | ||||
Previous Volumes in Series | xxiii | ||||
PART I Structure--Function Relations of Amiloride-Sensitive Sodium Channels | |||||
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3 | (1) | |||
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4 | (4) | |||
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8 | (7) | |||
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15 | (5) | |||
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20 | (5) | |||
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21 | (4) | |||
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25 | (1) | |||
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26 | (3) | |||
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29 | (1) | |||
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30 | (4) | |||
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34 | (3) | |||
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35 | (2) | |||
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37 | (2) | |||
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39 | (1) | |||
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39 | (3) | |||
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42 | (2) | |||
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44 | (7) | |||
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48 | (3) | |||
PART II Regulation of Sodium Channels | |||||
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51 | (1) | |||
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52 | (3) | |||
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55 | (10) | |||
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61 | (4) | |||
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65 | (1) | |||
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66 | (3) | |||
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69 | (2) | |||
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71 | (8) | |||
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79 | (2) | |||
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81 | (6) | |||
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82 | (5) | |||
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87 | (1) | |||
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88 | (1) | |||
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89 | (1) | |||
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89 | (1) | |||
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90 | (1) | |||
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90 | (1) | |||
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91 | (1) | |||
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91 | (1) | |||
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92 | (17) | |||
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92 | (11) | |||
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103 | (6) | |||
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109 | (2) | |||
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111 | (3) | |||
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114 | (8) | |||
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122 | (2) | |||
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124 | (9) | |||
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126 | (7) | |||
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133 | (2) | |||
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135 | (8) | |||
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143 | (5) | |||
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148 | (7) | |||
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149 | (6) | |||
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155 | (1) | |||
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156 | (2) | |||
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158 | (3) | |||
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161 | (2) | |||
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163 | (14) | |||
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175 | (2) | |||
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177 | (2) | |||
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179 | (6) | |||
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185 | (5) | |||
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190 | (7) | |||
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192 | (5) | |||
PART III Sodium Channels in the Lung | |||||
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197 | (1) | |||
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198 | (3) | |||
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201 | (9) | |||
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210 | (2) | |||
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212 | (7) | |||
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215 | (4) | |||
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219 | (2) | |||
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221 | (3) | |||
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224 | (6) | |||
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230 | (3) | |||
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233 | (1) | |||
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233 | (6) | |||
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234 | (5) | |||
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239 | (2) | |||
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241 | (1) | |||
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242 | (4) | |||
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246 | (2) | |||
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248 | (1) | |||
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249 | (7) | |||
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250 | (6) | |||
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256 | (1) | |||
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257 | (6) | |||
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263 | (10) | |||
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273 | (1) | |||
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274 | (5) | |||
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276 | (3) | |||
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279 | (3) | |||
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282 | (2) | |||
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284 | (1) | |||
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285 | (2) | |||
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287 | (10) | |||
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290 | (7) | |||
PART IV Sensory and Mechanical Transduction | |||||
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297 | (2) | |||
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299 | (5) | |||
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304 | (7) | |||
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311 | (4) | |||
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312 | (3) | |||
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315 | (2) | |||
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317 | (2) | |||
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319 | (7) | |||
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326 | (1) | |||
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327 | (1) | |||
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328 | (3) | |||
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331 | (8) | |||
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332 | (7) | |||
PART V Clinical Relevance | |||||
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339 | (3) | |||
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342 | (4) | |||
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346 | (5) | |||
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346 | (5) | |||
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351 | (1) | |||
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352 | (2) | |||
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354 | (5) | |||
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359 | (8) | |||
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367 | (3) | |||
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370 | (2) | |||
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372 | (9) | |||
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372 | (9) | |||
Index | 381 |
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