Behavioral Neurology

This ground-breaking book has been in print since 1974. Earlier editions of the book were seminal in delineating brain-behavior relationships; the current edition expands this theme using the most recent data from the neurosciences and molecular biology. Earlier editions focused on thebehavioral aspects of neurological conditions and the neurological aspects of psychiatric disorders. While this is still the focus of the book it has become clear from many research studies that the environmental events and emotions can alter brain structure , thus finally bringing a scientificbasis to psychological events. We have also added a valuable clinical chapter on differentiating the etiologies of disturbed behavior. This comprehensive text by two authors avoids the deluge of facts and duplicationof material often found in multi-authored texts to leave the leader with aconsistent approach to understanding and diagnosing disturbances of behavior. While the book is directed towards medical students, residents, psychiatrists and neurologists it has been widely used by many varied health professionals, pyschologists ,and lawyers.

Jonathan H. Pincus, M. D., has won many teaching awards and served as Vice President of the American Academy of Neurology. Among his numerous publications is Base Instincts, a book that deals with the causes of violence. He was on the faculty of Yale University School of Medicine before his appointment as Chair of the Department of Neurology at Georgetown University School of Medicine. He is presently Chief of Neurology, Veterans Affairs Medical Center, Washington, D.C., and Professor of Neurology, Georgetown University School of Medicine. Gary J. Tucker, M. D., has a wide array of experience in medical education, psychiatric research, and behavioral neurology. He started his academic career on the faculty of Yale University School of Medicine, and went on to serve as Chair of the Department of Psychiatry of Dartmouth College and the University of Washington School of Medicine. He is Professor Emeritus of Psychiatry and Behavioral Sciences, University of Washington School of Medicine.

Epilepsy and Behavior	p. 1
Idiopathic versus Symptomatic Epilepsy	p. 2
Clinical Genetic Studies	p. 3
Complex Partial Seizures--Temporal Lobe Origin	p. 4
Subjective Feelings	p. 5
Automatisms	p. 6
Complex Partial Seizures--Extratemporal Origin	p. 8
Electroencephalography and the Diagnosis of Epilepsy	p. 9
Abnormal Electroencephalogram without Epilepsy	p. 13
Pseudoseizures	p. 13
Therapy	p. 16
Blood Levels	p. 17
Surgery in Epilepsy	p. 22
Epileptogenesis, Cognitive, and Behavioral Deterioration	p. 24
Psychosis	p. 29
Affective Disorders	p. 34
Anxiety Disorders	p. 35
Sexual Behavior	p. 36
Personality Disturbance	p. 37
Violence, the Temporal Lobes, and the Limbic System	p. 38
Anatomy	p. 39
Physiological Psychology	p. 40
Aggression and Violence as an Epileptic-like Discharge of the Limbic System	p. 43
Episodic Dyscontrol	p. 45
Conclusion	p. 46
Violence and Neurobiology	p. 61
Brain Damage	p. 61
Antisocial Personality and the Frontal Lobe	p. 64
Neurotransmitters and Hormones	p. 65
Mental Illness	p. 66
Abuse	p. 67
Violence as a Complex Psycho-Social-Biologic Interaction	p. 69
Sociological Aspects of Violence	p. 72
Conclusion	p. 76
Schizophrenia	p. 85
Clinical Features	p. 89
Age at Onset and Gender	p. 92
Changing Diagnostic Criteria and Symptomatic Classifications	p. 93
Schizoaffective Disorder	p. 94
Personality Disorders and Schizophrenia	p. 95
Course and Natural History	p. 95
Differential Diagnosis	p. 97
Differentiating from Other Psychiatric Disorders	p. 97
Neurological Diseases	p. 98
Drug Reactions	p. 100
Sleep Disorders	p. 100
Biologic Basis of Schizophrenia	p. 100
Genetics	p. 100
Biochemical Findings	p. 103
Neurological Abnormalities in Schizophrenic Patients	p. 106
Minor, nonlocalizing neurological abnormalities	p. 106
Electroencephalographic data	p. 111
Neuroimaging	p. 112
Neuropathological findings	p. 115
Psychological Testing for Schizophrenia	p. 116
Arousal	p. 118
Treatment	p. 118
Conclusion	p. 119
Disorders of Cognitive Function	p. 133
Regional Syndromes	p. 135
Clinical Symptoms Associated with Frontal Lobe Dysfunction	p. 136
Clinical Symptoms Associated with Parietal Lobe Dysfunction	p. 139
Clinical Symptoms Associated with Temporal Lobe Dysfunction	p. 141
Other Symptoms of Cortical Dysfunction	p. 142
Aphasia	p. 142
Apraxia	p. 146
Agnosia	p. 146
Alexia and Agraphia	p. 146
Dysfunctions Associated with Severing the Corpus Callosum--Split Brains	p. 147
Diffuse Disorders of Cognitive Function--Delirium and Dementia	p. 150
Alzheimer's Disease	p. 154
Vascular Dementia	p. 157
Pick's Disease and Dementia of the Lewy Body Type	p. 157
Human Immunodeficiency Virus-1 Dementia	p. 158
Occult Hydrocephalus	p. 158
Cerebral White Matter Dysfunction and Cognitive Changes	p. 159
Depression in Dementia	p. 160
Neuropsychological Testing	p. 161
Cognitive Syndromes in Childhood	p. 161
Early Childhood Autism	p. 162
Attention-Deficit Hyperactivity Disorder	p. 164
Treatment	p. 166
Attention-deficit hyperactivity disorder in adults	p. 167
Conclusion	p. 167
Movement, Mood, and Obsessive-Compulsive Disorders	p. 177
Parkinson's Disease	p. 177
Pathogenesis	p. 181
L-dopa	p. 181
Stages of Parkinson's Disease	p. 182
Early dopamine deficiency--mildly symptomatic	p. 182
Moderate dopamine deficiency--wearing off--fluctuations of motor activity	p. 183
End stage of dopamine deficiency	p. 184
Protein Redistribution Diet	p. 186
Pharmacological Treatment	p. 186
The balance theory	p. 187
Surgical Treatments	p. 188
Transplants	p. 188
Pallidotomy/thalamotomy	p. 188
Brain stimulation	p. 189
Psychiatric Symptoms in Parkinson's Disease	p. 189
Depression	p. 189
Anxiety versus akathisia	p. 190
Painful dystonia	p. 191
Psychosis	p. 191
Dementia	p. 192
Etiology of Neurodegenerative Disorders	p. 193
Acute Drug-Induced Movement Disorders	p. 195
Tardive Movement Disorders	p. 195
Dystonia	p. 197
Dystonia and Mental Illness	p. 200
Chorea	p. 200
Treatment	p. 202
Motor Tics, Tourette's Syndrome, and Obsessive-Compulsive Disorder	p. 203
Affective Disorders	p. 205
Biologic Changes in Affective Disorders	p. 207
Structural changes	p. 207
Hypothalamic changes	p. 208
Anxiety and arousal	p. 209
Sleep	p. 209
Neurotransmitter changes	p. 210
Immune responses	p. 211
Genetics	p. 211
Stress and negative life events	p. 211
Treatment	p. 213
Conclusion	p. 214
Distinguishing Neurological from Psychiatric Symptoms	p. 229
Commonality of Neurological and Psychiatric Symptoms	p. 230
Panic Disorder/Hyperventilation as a Cause of Common Neurological Symptoms	p. 231
Somatization Disorder	p. 232
Unexplained Symptoms	p. 233
Conversion Disorders	p. 234
Specific Classical Conversion Symptoms	p. 235
Headache	p. 242
Conclusion	p. 245
Clinical Evaluation	p. 249
The Importance of the Clinical History	p. 250
Neurological Conditions Commonly Associated with a High Incidence of Psychiatric Complications	p. 254
The Clinical Examination of the Brain	p. 255
Cortical Functions	p. 256
Cognitive Functions	p. 257
Behaviors Associated with the Frontal Lobes	p. 258
Evaluation of the Frontal Lobes	p. 259
Cognitive aspects of the frontal lobe evaluation	p. 262
Mental Status Examination	p. 263
Imaging	p. 264
Clinical Laboratory Tests	p. 265
Electroencephalography	p. 265
Conclusion	p. 266
Index	p. 269
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