Bioactive Glasses and Glass-Ceramics Fundamentals and Applications

A Comprehensive and Critical Overview of Bioactive Glasses and Glass-Ceramics

Bioactive glasses and glass-ceramics are a versatile class of biocompatible materials that have an astonishing impact in biomedicine. Bioactive Glasses and Glass-Ceramics: Fundamentals and Applications presents topics on the functional properties, processing, and applications of bioactive glasses and glass-ceramics.

The primary use of bioactive glasses and glass-ceramics is to repair bone and dental defects; however, their full potential is yet to be fulfilled. Many of today’s achievements in regenerative medicine and soft tissue healing were unthinkable when research began. As a result, the research involving bioactive glasses and glass-ceramics is highly stimulating and continuously progresses across many different disciplines including chemistry, materials science, bioengineering, biology, and medicine. Topics relating to these disciplines and covered within the work include:

• Fundamentals on bioactive glasses and glass-ceramics, bioactive glasses in today’s market, and improvements and challenges for the future
• Scalability and other issues when taking bioactive glass from lab to industry/commercialization applications, plus clinical challenges
• Trending topics such as bioactive glass porous scaffolds, additive manufacturing of bioactive glasses, and nano-engineering of bioactive glasses
• The various bioactive glass compositions which have been developed as medical products in an expanding range of forms and applications

Bioactive Glasses and Glass-Ceramics: Fundamentals and Applications serves as a comprehensive and complete reference work on bioactive glasses and glass-ceramics for research and development (R&D) materials scientists, surgeons, and physicians, and leadership at glass and medical companies. Students and professors in fields of study pertaining to the aforementioned disciplines will also derive value from the work.

Francesco Baino, Ph.D., is an Associate Professor of Materials Science and Technology in the Applied Science and Technology Department at Politecnico di Torino, Italy. He is the author of 200 peer-reviewed articles and book chapters, around 100 contributions in conference proceedings, and three patents. He is a member of the American Ceramic Society.

Saeid Kargozar, Ph.D., is a Senior Assistant Professor of Tissue Engineering in the Department of Anatomy and Cell Biology at Mashhad University of Medical Sciences, Mashhad, Iran. He is the author of almost 90 peer-reviewed articles and book chapters, around 10 contributions in conference proceedings, and one patent. Dr. Kargozar is serving as a Guest Associate Editor and Referee for a couple of well-prestigious journals.

Preface

List of Contributors

Chapter 1 Glass crystallisation and glass-ceramics – an overview
Araceli de Pablos Martín, Delia S. Brauer

Chapter 2 Crystallisation of glasses and its impact on bioactivity and other properties
Araceli de Pablos Martín, Delia S. Brauer

Chapter 3  Bioactive glass S53P4 – from a statistically suggested composition to clinical success
Leena Hupa and Nina C. Lindfors

Chapter 4 Melt-Derived Bioactive Glasses: Beyond Silicate Glasses
Jonathan Massera

Chapter 5 Borate bioactive glass
Seiji Yamaguchi

Chapter 6 Fabrication of bioactive structures from Sol-gel derived bioactive glass.
D. Durgalakshmi and Anuj Kumar

Chapter 7 Processing of Bioactive Glass Scaffolds for Bone Tissue Engineering
Elisa Fiume, Carla Migneco, Saeid Kargozar, Enrica Verné, Francesco Baino

Chapter 8 Strong, tough bioactive glasses and composite scaffolds
Qiang Fu

Chapter 9 Nano-Bioactive Glass: Advances and Applications
Ahmed El-Fiqi

Chapter 10 Tailoring the osteogenic properties of bioactive glasses by incorporation of therapeutic ions for orthopedic applications
Sebastian Wilkesmann, Fabian Westhauser

Chapter 11 Bioactive glasses as carriers for the controlled release of therapeutic species
Min Zhu, Yufang Zhu

Chapter 12 Enhancing the biological performance of bioactive glasses by combination with phytotherapeutic compounds
Kanwal Ilyas, Aldo R. Boccaccini

Chapter 13 Bioactive Glass Based Coatings: Concepts for Improving the Biocompatibility of Implantable Materials
J. Fletcher, W. Alles, T.J. Keenan, A.W. Wren

Chapter 14 Laser cladding and laser direct glass deposition of bioactive glass and glass-ceramics
R. Comesaña, J. del Val, F. Quintero, A. Riveiro, F. Arias-González, M. Boutinguiza, F. Lusquiños, J. Pou

Chapter 15 Laser-assisted processing of CaSiO3‒Ca3(PO4)2 bioactive eutectic glasses and glass-ceramics for functional applications
Daniel J. Sola

Chapter 16 Molecular Dynamics (MD) Simulations of Bioactive Glasses and Glass-ceramics
Maziar Montazerian, Collin Wilkinson, John C. Mauro

Chapter 17 In Vitro and In Vivo Studies of Bioactive Glasses
Sadaf Batool, Zakir Hussain, Usman Liaqat

Chapter 18 Production of bioactive glass-ceramics for dental application through devitrification of glasses in the Na2O/K2O-CaO-MgO-SiO2-P2O5-CaF2 system
Konstantinos Dimitriadis, Dilshat U. Tulyaganov, Simeon Agathopoulos

Chapter 19 Applications of bioactive glasses for implants in the ear
Mario Milazzo, Glauco Cristofaro, Stefano Berrettini, and Serena Danti

Chapter 20 Bioactive glass: soft tissue reparative and regenerative applications
Shreyasi Majumdar, Smriti Gupta, Sairam Krishnamurthy

Chapter 21 Bioactive Glasses as Biologically Active Materials for Healing of Skin Wounds
Tina Mehrabi, Abdorreza S. Mesgar, Zahra Mohammadi

Chapter 22 Biocompatible Glasses Applied in Cancer Treatment: Magnetic Hyperthermia and Brachytherapy
Roger Borges, Ana Carolina S. Souza, Luis Antonio Genova, Joel Machado Jr., Giselle Zenker Justo, Juliana Marchi

Chapter 23 Bioactive glasses with antibacterial properties: mechanisms, compositions, and applications
Mostafa Awaid and Ilaria Cacciotti

Index

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