BIOS Instant Notes in Molecular Biology

, by Turner, Phil; McLennan, Alexander; Bates, Andy; White, Michael

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ISBN: 9780203967324 | 0203967321
Cover:
Copyright: 2/8/2007

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Summary

The new edition of the best selling Instant Notes in Molecular Biology is a fully updated and revised version of the previous successful and well-received text. It is an ideal companion to any undergraduate student studying molecular biology.

Cells and Macromolecules - Cellular classification
Subcellular organelles
Macromolecules
Large macromolecular assemblies
Protein Structure - Amino acids
Protein structure and function
Protein analysis
Properties of Nucleic Acids -Nucleic acid structure
Chemical and physical properties of nucleic acids
Spectroscopic and thermal properties of nucleic acids
DNA supercoiling
Prokaryotic and Eukaryotic Chromosome Structure - Prokaryotic chromosome structure
Chromatin structure
Eukaryotic chromosome structure
Genome complexity
The flow of genetic information
DNA Replication - DNA replication: an overview
Bacterial DNA replication
The cell cycle
Eukaryotic DNA replication
DNA Damage - Repair and Recombination
Mutagenesis
DNA damage
DNA repair
Recombination
Gene Manipulation - DNA cloning (an overview)
Preparation of plasmid DNA
Restriction enzymes and electrophoresis
Ligation, transformation and analysis of recombinants
Cloning Vectors - Design of plasmid vectors
Bacteriophage vectors
Cosmids and YACs
Eukaryotic vectors
Gene Libraries and Screening - Genomic libraries
cDNA libraries
Screening procedures
Analysis and Uses of Cloned DNA - Characterisation of clones
Sequencing nucleic acids
PCR
Organization of cloned genes
Mutagenesis of cloned genes
Applications of cloning
Transcription in Prokaryotes -Basic principles of transcription
Escherichia coli RNA polymerase
The promoter and its characterisation
Transcription initiation, elongation and termination
Regulation of Prokaryotic Transcription -The lac operon
The trp operon
Transcriptional regulation by alternative sigma factors
Transcription in Eukaryotes - The three polymerases, characterisation and function
RNA pol I genes: the ribosomal repeat
RNA pol III genes: 5S and tRNA genes
RNA pol II genes: promoters and enhancers
General transcription factors and Pol II initiation
Regulation of Transcription in Eukaryotes - Eukaryotic transcription factors
Examples of transcriptional regulation
RNA Processing and RNPs - rRNA processing and ribosomes
tRNA processing, RNase P and ribozymes
mRNA processing, hnRNPs and snRNPs
Alternative RNA processing
The Genetic Code and tRNA - The genetic code
tRNA structure and function.
Protein Synthesis - Aspects of protein synthesis
Mechanism of protein synthesis
Initiation in eukaryotes
Translational control and post translational events
Bacteriophage and Eukaryotic Viruses - Introduction to viruses
Bacteriophages
DNA viruses
RNA Viruses
Tumour Viruses and Oncogenes - Oncogenes found in tumour viruses
Categories of oncogenes
Tumour suppressor genes
Apoptosis
Functional Genomics and New Technologies - Omics
Genome Wide Analysis
Cell and Molecular Imaging
Transgenics and Stem Cell Technology
Bioinformatics - Omics
Bioinformatics
Genome Wide Experiments
Transgenics and Stem Cell Technology
Table of Contents provided by Publisher. All Rights Reserved.

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BIOS Instant Notes in Molecular Biology

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Table of Contents

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