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Myeloma; Biology and Management

Author(s): Malpas, Bergsagel, Kyle & Anderson
Edition: 3rd
ISBN10: 0721600069
ISBN13: 9780721600062
Cover: Hardcover
 
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List Price $179.00 
Our Price $171.03
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SummaryTable of Contents
Completely revised and updated, the 3rd Edition of this premier resource provides cutting-edge coverage of the epidemiology, immunology, and hematology of myelomaall in one convenient reference. A team of leading international authorities in myeloma research presents a worldwide perspective on the most recent developments in management and therapeutic options, as well as the latest clinical understanding of the disease.

  • Covers epidemiology, immunology, and hematology of myeloma all in a one-stop resource.


  • Provides new information on the biology, staging, and treatment of myeloma.
  • Offers new chapters on cytogenetics of multiple myeloma, molecular profiling of myeloma, prognostic factors, and novel agents for multiple myeloma, including those targeting tumors and microenvironment.
  • Presents the most recent breakthroughs in treatment, including various new drugs of proven efficacy such as Proteasome inhibitor Bortezomib, immunomodulatory drug Revamid, and controversial thalidomide, as well as treatment options just on the horizon.
  • Includes up-to-date information on gene micro-array profiling studies, which impact myeloma pathogenesis and identify targets of sensitivity versus resistance to new therapies.
PART I Pathophysiology
1(96)
Immunoglobulins
3(18)
D. E. Joshua
Multiple Myeloma and Plasma Cells: Cell-Cycle and Apoptotic Controls
21(14)
Selina Chen-Kiang
The Molecular Biology of Multiple Myeloma
35(24)
P. Leif Bergsagel
Michael Kuehl
Cytokines, Cytokine Receptors, and Signal Transduction in Human Multiple Myeloma
59(8)
Teru Hideshima
Dharminder Chauhan
Kenneth C. Anderson
Cytogenetics of Multiple Myeloma
67(16)
Rafael Fonseca
Gene Expression Profiling and Multiple Myeloma
83(14)
A. Keith Stewart
John Shaughnessy
PART II Clinical Features
97(104)
Multiple Myeloma: A History
99(18)
Robert A. Kyle
David P. Steensma
Epidemiology of Multiple Myeloma
117(42)
Anneclaire Deroos
Dalsu Baris
Noel S. Weiss
Lisa J. Herrinton
Clinical Presentation, Laboratory Diagnosis, and Indications for Treatment
159(16)
James S. Malpas
Jamie D. Cavenagh
Radiologic Features of Multiple Myeloma
175(14)
Lia A. Moulopoulos
Meletios A. Dimopoulos
Prognostic Factors and Classification for Multiple Myeloma (Contribution to Clinical Management)
189(12)
Jesus San Miguel
Rafael Fonseca
Philip R. Greipp
PART III Therapy of Myeloma
201(112)
Conventional-Dose Chemotherapy of Myeloma
203(16)
Daniel E. Bergsagel
A. Keith Stewart
High-Dose Therapy in Multiple Myeloma
219(10)
Faith E. Davies
J. Anthony Child
Novel Therapies for Multiple Myeloma
229(10)
Teru Hideshima
Paul G. Richardson
Kenneth C. Anderson
Management of Skeletal Complications
239(12)
James R. Berenson
Management of Renal, Hematologic, and Infectious Complications
251(18)
Joan Blade
Neurological Manifestations of Myeloma and Their Management
269(26)
Jeffrey Gawler
Myeloma: Patient and Caregiver Perspectives
295(18)
Michael S. Katz
Karin Isgur Bergsagel
Daniel E. Bergsagel
PART IV Other Disorders Associated with Paraproteinemia
313(116)
Monoclonal Gammopathies of Undetermined Significance
315(38)
Robert A. Kyle
Joan Blade
S. Vincent Rajkumar
Plasmacytoma
353(8)
James S. Malpas
Jamie D. Cavenagh
Amyloidosis
361(24)
Philip N. Hawkins
Heavy Chain Diseases
385(26)
Dietlind L. Wahner-Roedler
Robert A. Kyle
Waldenstrom's Macroglobulinemia
411(18)
Robert A. Kyle
Rafael Fonseca
Index 429

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