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Sleisenger & Fordtran's Gastrointestinal & Liver Disease

Author(s): Feldman, Mark
ISBN10: 0721600107
ISBN13: 9780721600109
Cover: Hardcover
 
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Table of Contents
Section One BIOLOGY OF THE GASTROINTESTINAL TRACT AND LIVER
Gastrointestinal Hormones and Neurotransmitters
3(18)
Michael A. Shetzline
Rodger A. Liddle
Cellular Communication
3(2)
Neural Regulation of the Gastrointestinal Tract
5(1)
Peptide Hormones of the Gastrointestinal Tract
6(3)
Other Chemical Messengers of the Gastrointestinal Tract
9(2)
Signal Transduction
11(3)
Regulation of Gastrointestinal Growth by Hormones and Transmitters
14(3)
Regulation of Gastrointestinal Hormones by Intraluminal Releasing Factors
17(4)
Mucosal Immunology and Mechanisms of Gastrointestinal Inflammation
21(32)
R. Balfour Sartor
Mucosal Immune Responses
21(13)
Inflammatory Responses
34(19)
Cellular Growth and Neoplasia
53(18)
Anil K. Rustgi
Daniel K. Podolsky
Mechanisms of Normal Cell Homeostasis: Proliferation and Programmed Cell Death (Apoptosis)
53(1)
Regulation of Normal Cell Proliferation: Signaling Pathways That Mediate Cell Growth
54(2)
Mechanisms of Oncogenesis
56(2)
Neoplasia-Associated Genes
58(5)
Biologic Features of Tumor Metastasis
63(1)
Summary of Molecular Mechanisms of Gastrointestinal Cancers
64(1)
Diagnostic Strategies: Current and Future Approaches
64(7)
Section Two APPROACH TO PATIENTS WITH SYMPTOMS AND SIGNS
Abdominal Pain, Including the Acute Abdomen
71(13)
Robert E. Glasgow
Sean J. Mulvihill
Anatomic Basis of Pain
71(1)
Stimulants of Pain
72(1)
Types of Pain
Approach to the Patient with Acute Abdominal Pain
73(7)
Approach to the Patient with Chronic Abdominal Pain
80(4)
A Short Treatise on Bowel Sounds
82(2)
Braden Kuo
Lawrence S. Friedman
Chronic Abdominal Pain (With Emphasis on Functional Abdominal Pain Syndrome)
84(9)
Douglas A. Drossman
Definition and Classification of Functional Abdominal Pain Syndrome
84(1)
Epidemiology and Impact on Health Care Systems
84(1)
Pathophysiology of Chronic Pain
85(3)
Clinical Features
88(1)
Diagnosis and Differential Diagnosis
89(1)
Treatment
89(4)
Dysphagia, Odynophagia, Heartburn, and Other Esophageal Symptoms
93(9)
Joel E. Richter
Dysphagia
93(2)
Odynophagia
95(1)
Heartburn (Pyrosis)
95(2)
Globus Sensation
97(1)
Chest Pain
97(2)
Respiratory; Ear, Nose, and Throat; and Cardiac Symptoms
99(3)
Dyspepsia
102(17)
Kenneth R. McQuaid
Definition
102(1)
Epidemiology
103(1)
Causes of Organic Dyspepsia
103(2)
Functional (Nonulcer) Dyspepsia
105(3)
Approach to Uninvestigated Dyspepsia
108(3)
Uncomplicated Dyspepsia: Empirical Therapy versus Early Endoscopy
111(2)
Treatment of Functional Dyspepsia
113(6)
Nausea and Vomiting
119(12)
Makau Lee
Act of Vomiting
119(1)
Neural Pathways and Pathophysiology of Vomiting
120(1)
Clinical Approach to Patients with Nausea and Vomiting
121(2)
Specific Syndromes Associated with Vomiting
123(5)
Consequences of Vomiting
128(1)
Therapy of Vomiting
128(3)
Diarrhea
131(24)
Lawrence R. Schiller
Joseph H. Sellin
Definition of Diarrhea
131(1)
Pathophysiology and Mechanisms of Diarrhea
131(4)
Clinical Classification: Clues to Diagnosis
135(1)
Differential Diagnosis of Diarrhea
136(2)
Evaluation of the Patient with Diarrhea
138(7)
Nonspecific Treatment of Diarrhea
145(1)
Highlights of Selected Diarrheal Syndromes
146(9)
Intestinal Gas
155(9)
Fabrizis L. Suarez
Michael D. Levitt
Factors Influencing the Quantity of Bowel Gases
155(1)
Volume and Composition of Bowel Gas
155(1)
Sources of Bowel Gas
155(4)
Clinical Gas Problems
159(5)
Fecal Incontinence
164(17)
Lawrence R. Schiller
Prevalence
164(1)
Mechanisms of Continence and Fecal Incontinence
164(2)
Differential Diagnosis of Fecal Incontinence
166(1)
Evaluation of Patients with Fecal Incontinence
167(4)
Treatment
171(4)
Management of Specific Situations
175(6)
Constipation
181(30)
J. E. Lennard-Jones
Presenting Symptoms
181(1)
Epidemiology
182(1)
Clinical Definition and Classification
183(1)
Pathophysiology
184(5)
Constipation as a Manifestation of Systemic Disorders
189(1)
Constipation as a Manifestation of Central Nervous System Disease or Extrinsic Nerve Supply to the Gut
189(1)
Constipation Secondary to Structural Disorders of the Colon, Rectum, Anus, and Pelvic Floor
190(2)
Drug Treatment That May Cause or Aggravate Constipation
192(1)
Psychological Disorders as Causes of or Aggravating Factors in Constipation
193(1)
Clinical Assessment
193(1)
Investigation
194(2)
Medical Treatment
196(6)
Defecation Training, Biofeedback, and Other Behavioral Treatments
202(1)
Surgical Treatment
203(1)
Particular Clinical Problems
204(7)
Gastrointestinal Bleeding
211(38)
Don C. Rockey
Clinical Presentation
211(3)
Acute Upper Gastrointestinal Bleeding
214(12)
Acute Lower Gastrointestinal Bleeding
226(6)
Occult and Obscure Bleeding
232(17)
Jaundice
249(16)
Steven D. Lidofsky
Determinants of Serum Bilirubin Concentration
249(1)
Differential Diagnosis of Jaundice
250(6)
Diagnostic Approach to the Patient with Jaundice
256(4)
Therapeutic Options
260(5)
Section Three NUTRITION IN GASTROENTEROLOGY
The Malnourished Patient: Nutritional Assessment and Management
265(22)
Samuel Klein
Khursheed N. Jeejeebhoy
Basic Nutritional Concepts
265(6)
Starvation
271(1)
Malnutrition
271(6)
Refeeding the Malnourished Patient
277(2)
Patients with Severe Malabsorption
279(8)
Enteral and Parenteral Nutrition
287(23)
Samuel Klein
Deborah C. Rubin
Enteral Nutrition
287(8)
Parenteral Nutrition
295(5)
Clinical Applications of Nutrition Support
300(10)
Anorexia Nervosa, Bulimia Nervosa, and Obesity
310(29)
Margo A. Denke
Importance of Body Weight as a Surrogate for Health
310(3)
Disorders in Energy Balance
313(1)
Anorexia Nervosa
313(5)
Bulimia Nervosa
318(3)
Obesity
321(18)
Section Four TOPICS INVOLVING MULTIPLE ORGANS
Oral Disease and Oral-Cutaneous Manifestations of Gastrointestinal and Liver Disease
339(20)
Ginat W. Mirowski
Tsu-Yi Chuang
Disorders of the Mouth and Tongue
339(1)
Mucocutaneous Candidiasis
340(1)
Mucocutaneous Features of HIV Infection
340(2)
Mucocutaneous Ulcerative Disease
342(1)
Vesiculobullous Diseases
343(1)
Lichen Planus
344(1)
Cutaneous Manifestations of Intestinal Disease Including Inflammatory Bowel Disease
345(1)
Vascular and Connective Tissue Disorders
346(3)
Cutaneous Markers Associated with Gastrointestinal Malignancies
349(3)
Cutaneous Manifestations of Liver Disease
352(2)
Parasitic Diseases of the Gut and Skin
354(1)
Dermatitis Herpetiformis and Celiac Sprue
354(1)
Vitamin Deficiencies
355(4)
Diverticula of the Hypopharynx, Esophagus, Stomach, Jejunum, and Ileum
359(10)
Rohan Jeyarajah
William Harford
Zenker's Diverticula
359(2)
Diverticula of the Esophageal Body
361(1)
Esophageal Intramural Pseudodiverticula
362(1)
Gastric Diverticula
363(1)
Duodenal Diverticula
364(1)
Intramural Duodenal Diverticula
365(1)
Jejunal Diverticula
366(3)
Abdominal Hernias and Their Complications, Including Gastric Volvulus
369(17)
William Harford
Rohan Jeyarajah
Diaphragmatic Hernias
369(4)
Gastric Volvulus
373(2)
Inguinal and Femoral Hernias (Groin Hernias)
375(2)
Other Ventral Hernias
377(2)
Pelvic and Perineal Hernias
379(1)
Lumbar Hernias
380(1)
Internal Hernias
380(6)
Foreign Bodies and Bezoars
386(13)
Patrick R. Pfau
Gregory G. Ginsberg
Foreign Bodies
386(9)
Bezoars
395(4)
Caustic Injury to the Upper Gastrointestinal Tract
399(9)
Peter M. Loeb
Michael J. Nunez
Caustic Agents
399(5)
Button Battery Ingestion
404(4)
Nonsteroidal Anti-inflammatory Drug Injury
408(23)
Byron Cryer
Epidemiology
408(1)
Mechanisms of Toxicity of Nonsteroidal Anti-inflammatory Drugs
408(4)
Clinical Manifestations of Nonsteroidal Anti-inflammatory Drug Injury Throughout the Gastrointestinal Tract
412(12)
Therapeutic Effects of Nonsteroidal Anti-inflammatory Drugs
424(7)
Abdominal Abscesses and Gastrointestinal Fistulas
431(15)
Joseph P. Minei
Julie G. Champine
Abdominal Abscesses
431(7)
Gastrointestinal Fistulas
438(8)
Protein-Losing Gastroenteropathy
446(7)
Karen E. Kim
Definition
446(1)
Normal Physiology
446(1)
Pathophysiology
446(1)
Clinical Manifestations
446(2)
Diseases Associated with Protein-Losing Gastroenteropathy
448(1)
Diagnosis
449(2)
Treatment
451(2)
Gastrointestinal Lymphomas, Including Immunoproliferative Small Intestinal Disease
453(20)
Robert H. Collins
Non-Hodgkin's Lymphoma: Background
453(2)
General Principles of Lymphoma Management
455(1)
Gastric Lymphomas
455(6)
Small-Bowel Lymphomas
461(6)
Other Sites
467(1)
Immunodeficiency-Related Lymphomas
467(6)
Gastrointestinal Complications of Solid Organ and Hematopoietic Cell Transplantation
473(14)
Sally Weisdorf-Schindele
John R. Lake
Overview of Complications
473(4)
Complications of Solid Organ Transplantation
477(4)
Complications of Hematopoietic Cell Transplantation
481(6)
Gastrointestinal Consequences of Infection with Human Immunodeficiency Virus
487(20)
C. Mel Wilcox
Evaluation and Management of Gastrointestinal and Hepatobiliary Symptoms in AIDS
488(1)
Diarrhea
488(5)
Odynophagia and Dysphagia
493(3)
Abdominal Pain
496(1)
Anorectal Disease
497(1)
Gastrointestinal Bleeding
498(1)
Hepatomegaly and Jaundice
499(8)
Gastrointestinal Manifestations of Systemic Disease
507(32)
David D. Kim
James C. Ryan
Rheumatologic and Collagen Diseases
507(66)
Neoplastic Diseases
573
Hematologic Diseases
514(3)
Endocrine Diseases
517(4)
Renal Diseases
521(1)
Neurologic Disease
522(4)
Pulmonary Diseases/ICU Patients
526(1)
Cardiac Diseases
526(1)
Infiltrative Disease
526(2)
Disorders of Lipid Metabolism
528(1)
Pregnancy
529(10)
Complications of Gastrointestinal Endoscopy
539(12)
Marta L. Davila
Emmet B. Keeffe
General Complications
540(3)
Complications of Upper Endoscopy
543(1)
Complications of Sigmoidoscopy and Colonoscopy
544(7)
Section Five ESOPHAGUS
Anatomy, Histology, Embryology, and Developmental Anomalies of the Esophagus
551(10)
John D. Long
Roy C. Orlando
Anatomy and Histology
551(3)
Embryology
554(1)
Developmental Anomalies
554(7)
Esophageal Motor and Sensory Function and Motor Disorders of the Esophagus
561(38)
Ray E. Clouse
Nicholas E. Diamant
Motor and Sensory Innervation
562(3)
Coordinated Esophageal Motor Activity
565(5)
Pathogenesis and Categorization of Motor Disorders
570(1)
Diagnosing Motor Disorders
571(3)
Disorders of the UES and Cervical Esophageal Region
574(3)
Achalasia
577(7)
Other Hypermotility Disorders of the Distal Esophagus and LES (Spastic Disorders)
584(4)
Esophageal Hypomotility
588(11)
Gastroesophageal Reflux Disease and Its Complications, Including Barrett's Metaplasia
599(24)
Peter J. Kahrilas
John E. Pandolfino
Definitions and Epidemiology
599(1)
Histopathology of Gastroesophageal Reflux Disease
600(1)
Pathogenesis
601(6)
Clinical Presentation and Natural History
607(2)
Management
609(6)
Barrett's Metaplasia, Dysplasia, and Adenocarcinoma
615(8)
Esophageal Disorders Caused by Infection, Systemic Illness, Medications, Radiation, and Trauma
623(24)
David Kearney
George B. McDonald
Infections
623(8)
Systemic Illness
631(3)
Medications and Radiation Injury
634(3)
Trauma
637(10)
Esophageal Tumors
647(28)
Gregory G. Ginsberg
David E. Fleischer
Malignant Epithelial Tumors
647(18)
Other Malignant Epithelial Tumors
665(1)
Benign Epithelial Tumors of the Esophagus
665(1)
Malignant Nonepithelial Tumors
666(1)
Benign Nonepithelial Tumors
666(9)
Section Six STOMACH AND DUODENUM
Anatomy, Histology, Embryology, and Developmental Anomalies of the Stomach and Duodenum
675(16)
Carol A. Redel
Anatomy of the Stomach
675(5)
Anatomy of the Duodenum
680(2)
Congenital Anomalies of the Stomach and Duodenum
682(9)
Gastric Motor and Sensory Function, and Motor Disorders of the Stomach
691(24)
Eamonn M. M. Quigley
Gastric Motor Physiology
691(10)
Clinical Assessment of Gastric Motor Function and Dysfunction
701(2)
Gastric Motor Disorders
703(5)
Therapy
708(7)
Gastric Secretion
715(17)
Mark Feldman
Physiology
715(6)
Quantitative Aspects of Acid Secretion in Humans
721(2)
Mucus/Bicarbonate Secretion
723(1)
Secretion of Other Electrolytes (K+, Na+, Cl-)
724(1)
Pepsinogens and Other Gastric Aspartic Proteases
725(1)
Human Gastric Lipase
725(1)
Intrinsic Factor
725(1)
Gastric Secretion in Disease
726(6)
Helicobacter Pylori
732(15)
Walter L. Peterson
David Y. Graham
Epidemiology
732(2)
Virulence Factors
734(1)
Acute Infection
735(1)
Chronic Infection
736(2)
Diagnosis
738(2)
Treatment
740(3)
Immunization
743(4)
Peptic Ulcer Disease and Its Complications
747(35)
Stuart Jon Spechler
Pathophysiology of Peptic Ulceration
748(6)
Epidemiology
754(2)
Clinical Features of Uncomplicated Peptic Ulcer Disease
756(1)
Diagnostic Tests
757(1)
Treatments for Peptic Ulcer Disease
758(10)
Specific Management Recommendations
768(1)
Complications of Peptic Ulcer Disease
769(2)
Physiologic Stress and Peptic Injury
771(1)
Cameron Ulcers (Linear Gastric Erosions in Hiatal Hernias)
772(10)
Zollinger-Ellison Syndrome and Other Hypersecretory States
782(15)
Joseph R. Pisegna
Zollinger-Ellison Syndrome
782(10)
Other Gastric Hypersecretory States
792(5)
Current Role of Surgery in Peptic Ulcer Disease
797(13)
Robert V. Rege
Daniel B. Jones
Historical Basis for the Surgical Treatment of Peptic Disease
797(1)
Physiologic Basis for Peptic Ulcer Surgery
798(1)
Operations for Duodenal Ulcers
798(4)
Roux-en-Y Gastrojejunostomy
802(1)
Operations for Benign Gastric Ulcers
802(1)
Early Postoperative Complications
803(1)
Late Postoperative Complications
804(1)
Disorders Associated with Delayed Gastric Emptying/Gastric Stasis
804(1)
Bile (Alkaline) Reflux Gastritis
805(1)
Gastric Adenocarcinoma
805(1)
Syndromes Associated with Rapid Gastric Emptying
806(1)
Current Controversies on the Role of Surgery in Peptic Ulcer Disease
806(4)
Gastritis and Other Gastropathies
810(19)
Edward L. Lee
Mark Feldman
Classification
810(1)
Chronic, Nonspecific Gastritides
810(3)
Infectious Gastritis
813(3)
Granulomatous Gastritides
816(1)
Distinctive Forms of Gastritis
817(1)
Miscellaneous Forms of Gastritis
817(2)
Reactive Gastropathies (Acute Erosive Gastritis)
819(2)
Hyperplastic Gastropathies
821(8)
Tumors of the Stomach
829(30)
Theodore J. Koh
Timothy C. Wang
Adenocarcinoma
829(16)
Gastric Lymphoma
845(1)
Gastric Carcinoid Tumors
846(1)
Gastrointestinal Stromal Tumors
847(1)
Miscellaneous Tumors
848(11)
Section Seven PANCREAS
Anatomy, Histology, Embryology, and Developmental Anomalies of the Pancreas
859(12)
David J. Magee
J. Steven Burdick
History
859(1)
Normal Anatomy
859(3)
Normal Histology and Ultrastructure
862(4)
Embryology
866(1)
Developmental Anomalies
867(4)
Pancreatic Physiology and Secretory Testing
871(10)
Stephen J. Pandol
Functional Anatomy
871(1)
Composition of Exocrine Pancreatic Secretions
871(2)
Functions of the Major Digestive Enzymes
873(1)
Digestive Enzyme Synthesis and Transport
873(1)
Cellular Regulation of Enzyme Secretion
874(1)
Organ Physiology
875(2)
Pancreatic Secretory Function Tests
877(4)
Hereditary and Childhood Disorders of the Pancreas, Including Cystic Fibrosis
881(32)
David C. Whitcomb
Genetic Basis of Congenital Disorders of Morphogenesis
881(3)
Ductal Abnormalities
884(1)
Inherited Syndromes with Major Pancreatic Manifestations
884(14)
Gene Mutations Predisposing to Acute and Chronic Pancreatitis
898(4)
Inherited Disorders of Metabolism Causing Pancreatitis
902(1)
Pancreatic Insufficiency Syndromes
903(1)
Acquired Pancreatic Disease in Children
904(9)
Acute Pancreatitis
913(30)
Eugene P. DiMagno
Suresh Chari
Incidence and Definition
913(1)
Pathology
914(1)
Pathogenesis
914(3)
Pathophysiology
917(1)
Predisposing Conditions
917(5)
Clinical Presentation
922(1)
Laboratory Diagnosis
923(2)
Radiologic Diagnosis
925(2)
Differential Diagnosis of Acute Pancreatitis
927(1)
Distinguishing Alcoholic From Gallstone Pancreatitis
927(1)
Predictors of Severity of Pancreatitis
928(2)
Treatment
930(5)
Complications
935(1)
Prognosis
936(7)
Chronic Pancreatitis
943(27)
Chris E. Forsmark
Definition
943(1)
Epidemiology and Natural History (Prognosis)
943(1)
Pathology
944(1)
Pathophysiology
944(1)
Etiology
945(2)
Clinical Presentation
947(2)
Diagnosis
949(6)
Treatment
955(7)
Complications
962(8)
Pancreatic Cancer, Cystic Pancreatic Neoplasms, and Other Nonendocrine Pancreatic Tumors
970(18)
Carlos Fernandez-del Castillo
Ramon E. Jimenez
Pancreatic Cancer
970(9)
Cystic Tumors of the Pancreas
979(4)
Other Nonendocrine Pancreatic Tumors
983(5)
Pancreatic Endocrine Tumors
988(31)
Robert T. Jensen
Jeffrey A. Norton
General Aspects
988(2)
Multiple Endocrine Neoplasia
990(1)
Other Inherited Syndromes Associated with Pancreatic Endocrine Tumors
991(1)
Insulinoma
991(3)
Glucagonoma
994(3)
VIPoma
997(3)
Somatostatinoma
1000(2)
GRFoma
1002(1)
PPoma and Nonfunctioning Pancreatic Endocrine Tumors
1003(1)
Other Pancreatic Endocrine Tumors
1004(1)
Tumor Localization
1005(2)
Management of Metastatic Pancreatic Endocrine Tumors
1007(12)
Section Eight BILIARY TRACT
Anatomy, Histology, Embryology, Developmental Anomalies, and Pediatric Disorders of the Biliary Tract
1019(24)
Frederick J. Suchy
Development of the Liver and Biliary Tract
1019(2)
Anatomy of the Biliary Tract and Gallbladder
1021(3)
Congenital Anomalies of the Extrahepatic Ducts
1024(1)
Congenital Anomalies of the Gallbladder
1024(1)
Disorders of the Biliary Tract in Children
1024(2)
Diseases of the Bile Ducts
1026(10)
Diseases of the Gallbladder
1036(7)
Motility and Dysmotility of the Biliary Tract and Sphincter of Oddi
1043(8)
Grace H. Elta
Anatomy and Physiology
1043(1)
Gallbladder Dyskinesia
1043(1)
Sphincter of Oddi Dysfunction
1044(4)
Sphincter of Oddi Dysfunction in Pancreatitis
1048(1)
Failure to Respond to Biliary Sphincterotomy in Sphincter of Oddi Dysfunction
1048(3)
Bile Secretion and the Enterohepatic Circulation of Bile Acids
1051(14)
Paul A. Dawson
Bile Acid Synthesis and Secondary Metabolism
1052(2)
The Enterohepatic Circulation
1054(2)
Hepatic Bile Acid Transport and Bile Secretion
1056(2)
Intestinal Bile Acid Transport
1058(1)
Disorders of the Enterohepatic Circulation
1059(3)
Bile Acid Therapy, Sequestrants, Transport Inhibitors
1062(3)
Gallstone Disease and Its Complications
1065(26)
Jay D. Horton
Lyman E. Bilhartz
Epidemiology, Risk Factors, Pathogenesis, and Natural History of Gallstones
1065(8)
Clinical Manifestations of Gallstone Disease
1073(18)
Surgical Management of Gallstone Disease and Postoperative Complications
1091(16)
Robert E. Glasgow
Sean J. Mulvihill
Surgery for Cholelithiasis
1087(4)
Indications for Cholecystectomy
1091(4)
Surgery for Choledocholithiasis
1095(1)
Bile Duct Stricture
1096(1)
Postcholecystectomy Syndrome
1097(1)
Gallstones, Cholecystectomy, and Cancer
1098(9)
Nonsurgical Management of Gallstone Disease
1107(9)
Gustav Paumgartner
General Aspects
1107(1)
Oral Bile Acid Dissolution Therapy
1108(2)
Extracorporeal Shock-Wave Lithotripsy
1110(3)
Extracorporeal Shock-Wave Lithotripsy of Bile Duct Stones
1113(1)
Recurrence of Gallstones
1113(1)
Choice of Treatment
1114(2)
Acalculous Cholecystitis, Cholesterolosis, Adenomyomatosis, and Polyps of the Gallbladder
1116(15)
Lyman E. Bilhartz
Acalculous Biliary Pain
1116(2)
Acute Acalculous Cholecystitis
1118(3)
Cholesterolosis of the Gallbladder
1121(2)
Adenomyomatosis of the Gallbladder
1123(2)
Polyps of the Gallbladder
1125(6)
Sclerosing Cholangitis and Recurrent Pyogenic Cholangitis
1131(22)
Uma Mahadevan
Nathan M. Bass
Sclerosing Cholangitis
1131(2)
Primary Sclerosing Cholangitis
1133(11)
Recurrent Pyogenic Cholangitis
1144(9)
Tumors of the Gallbladder, Bile Ducts, and Ampulla
1153(14)
Taylor A. Sohn
Keith D. Lillemoe
Gallbladder Tumors
1153(5)
Tumors of the Extrahepatic Biliary Tree
1158(3)
Tumors of the Ampulla of Vater
1161(6)
Endoscopic and Radiologic Treatment of Biliary Disease
1167(28)
James W. Ostroff
Jeanne M. LaBerge
General Principles
1167(1)
Procedural Techniques
1168(11)
Treatment of Specific Diseases
1179(16)
Section Nine LIVER
Anatomy, Histology, Embryology, and Developmental Anomalies of the Liver
1195(7)
Ian R. Wanless
Surface Anatomy
1195(1)
Segmental Anatomy
1195(2)
Variations in Surface Anatomy
1197(1)
Large Vessels of the Liver
1197(1)
Lymph Vessels
1198(1)
Nerve Supply
1198(1)
Biliary System
1198(1)
Microanatomy
1199(3)
Liver Physiology and Metabolic Function
1202(25)
Andrew Stolz
Hepatic Architecture
1202(1)
Excretory Pathway
1203(1)
Introduction to Liver Metabolism
1204(1)
Carbohydrate Metabolism
1204(4)
Synthesis and Metabolism of Fatty Acids
1208(2)
Lipid Transport
1210(5)
Liver Disease and Lipid Abnormalities
1215(1)
Serum Proteins Synthesized by the Liver
1216(3)
Fat-Soluble Vitamins
1219(3)
Hepatic Regeneration
1222(1)
Apoptosis
1223(4)
Biochemical Liver Tests
1227(13)
Timothy J. Davern
Bruce F. Scharschmidt
Biochemical Liver Tests
1227(4)
Characteristic Biochemical Patterns: Interpretation and Approach
1231(3)
Frequently Encountered Clinical Problems
1234(3)
Quantitative Tests of Liver Function
1237(3)
Inherited Metabolic Disorders of the Liver
1240(21)
Mike A. Leonis
William F. Balistreri
α1-Antitrypsin Deficiency
1240(3)
Glycogen Storage Disease
1243(2)
Congenital Disorders of Glycosylation
1245(1)
Porphyrias
1246(3)
Tyrosinemia
1249(2)
Urea Cycle Defects
1251(2)
Bile Acid Synthesis and Transport Defects
1253(3)
Cystic Fibrosis
1256(1)
Mitochondrial Liver Diseases
1256(5)
Hereditary Hemochromatosis
1261(8)
Bruce R. Bacon
Robert S. Britton
Causes of Iron Overload
1261(1)
Pathophysiology
1262(2)
Clinical Manifestations
1264(1)
Diagnosis
1264(2)
Treatment and Prognosis
1266(1)
Family Screening
1267(2)
Wilson Disease
1269(9)
Diane W. Cox
Eve A. Roberts
The Copper Pathway
1269(1)
The Basic Molecular Defect
1269(1)
Clinical Features
1270(2)
Pathology
1272(1)
Diagnosis
1272(3)
Treatment
1275(1)
Prognosis
1276(2)
Viral Hepatitis
1278(65)
Marina Berenguer
Teresa L. Wright
Hepatitis A Virus
1278(7)
Hepatitis B Virus
1285(18)
Hepatitis C Virus
1303(20)
Hepatitis D Virus
1323(5)
Hepatitis E Virus
1328(4)
Hepatitis G Virus and the GB Agents
1332(1)
TT Virus
1333(1)
Sanban, Tonban, TLMV, and SEN Viruses
1334(9)
Liver Abscess and Bacterial, Parasitic, Fungal, and Granulomatous Liver Disease
1343(21)
Raymond T. Chung
Lawrence S. Friedman
Liver Abscess
1343(3)
Bacterial and Spirochetal Infections of the Liver
1346(5)
Parasitic Diseases That Involve the Liver
1351(8)
Fungal Liver Disease
1359(1)
Granulomatous Liver Disease
1360(1)
Bacillary Angiomatosis and Acquired Immunodeficiency Syndrome
1361(3)
Vascular Diseases of the Liver
1364(11)
Daniel F. Schafer
Michael F. Sorrell
Budd-Chiari Syndrome
1364(3)
Veno-occlusive Disease
1367(1)
Portal Vein Thrombosis
1368(2)
Ischemic Hepatitis
1370(1)
Congestive Hepatopathy
1370(1)
Peliosis Hepatis
1371(1)
Hepatic Artery Aneurysm
1372(1)
Atherosclerosis
1372(1)
Polyarteritis Nodosa
1372(1)
Polymyalgia Rheumatica
1373(2)
Alcoholic Liver Disease
1375(18)
Jacquelyn J. Maher
Epidemiology
1375(1)
Ethanol Metabolism
1375(2)
Pathogenesis of Alcoholic Liver Injury
1377(2)
Cofactors in the Development of Alcoholic Liver Disease
1379(1)
Diagnosis
1380(3)
Complications
1383(1)
Treatment
1384(3)
Prognosis
1387(6)
Nonalcoholic Fatty Liver Disease
1393(10)
Anna Mae Diehl
Fred Poordad
Etiology
1393(1)
Pathogenesis
1393(2)
Clinical Features
1395(2)
Histologic Features
1397(1)
Prognosis
1397(1)
Treatment: Current and Future
1398(2)
Focal Fatty Liver
1400(3)
Liver Disease Caused by Drugs, Anesthetics, and Toxins
1403(45)
Geoffrey C. Farrell
Definitions and General Importance of Drugs and Toxins as Causes of Liver Disease
1403(1)
Epidemiology
1404(2)
Pathophysiology
1406(4)
Clinicopathologic Features of Drug-Induced Liver Disease
1410(3)
Prevention and Management
1413(1)
Dose-Dependent Hepatotoxicity
1414(5)
Drug-Induced Acute Hepatitis
1419(4)
Drug-Induced Granulomatous Hepatitis
1423(1)
Drug-Induced Chronic Hepatitis
1423(2)
Drug-Induced Cholestasis
1425(2)
Chronic Cholestasis
1427(1)
Liver Disease Caused by Anesthetic Agents and Jaundice in the Postoperative Period
1428(2)
Drug-Induced Steatohepatitis, Hepatic Fibrosis, and Cirrhosis
1430(3)
Vascular Toxicity
1433(2)
Liver Tumors
1435(2)
Complementary and Alternative Medicines and Environmental Agents
1437(11)
Pregnancy-Related Hepatic and Gastrointestinal Disorders
1448(14)
Caroline A. Riely
Rene Davila
Liver Problems Unique to Pregnancy
1448(6)
Liver Disorders Complicating Pregnancy
1454(1)
Gastrointestinal Disorders Complicating Pregnancy
1454(8)
Autoimmune Hepatitis
1462(12)
Albert J. Czaja
Diagnostic Criteria
1462(1)
Pathogenesis
1462(2)
Subclassifications
1464(2)
Variant Forms
1466(1)
Prevalence
1467(1)
Prognostic Indices
1467(1)
Clinical Manifestations
1468(1)
Treatment
1469(1)
Treatment Results
1470(1)
Future Directions
1471(3)
Primary Biliary Cirrhosis
1474(13)
Paul Angulo
Keith D. Lindor
Epidemiology
1474(1)
Pathogenesis
1475(1)
Clinical Features
1476(1)
Diagnosis
1476(2)
Natural History
1478(1)
Medical Treatment
1479(1)
Complications of Chronic Cholestasis and Their Management
1480(2)
Liver Transplantation
1482(1)
Autoimmune Cholangitis or Anti-Mitochondrial Antibody-Negative Primary Biliary Cirrhosis
1483(4)
Portal Hypertension and Variceal Bleeding
1487(30)
Nathan M. Bass
Francis Y. Yao
Etiology and Pathophysiology of Portal Hypertension
1487(7)
Anatomic Sites of Collateral Formation and Bleeding
1494(1)
Natural History and Prognosis of Variceal Hemorrhage
1495(2)
Diagnosis
1497(1)
Management
1498(19)
Ascites and Spontaneous Bacterial Peritonitis
1517(26)
Bruce A. Runyon
Pathogenesis of Ascites Formation
1517(1)
Clinical Features of Ascites
1518(1)
Diagnosis
1519(8)
Differential Diagnosis
1527(1)
Complications of Ascites
1528(7)
Treatment of Ascites
1535(4)
Summary of Treatment of Patients with Cirrhosis and Ascites
1539(1)
Prognosis
1540(3)
Hepatic Encephalopathy, Hepatopulmonary Syndromes, Hepatorenal Syndrome, Coagulopathy, and Endocrine Complications of Liver Disease
1543(24)
J. Gregory Fitz
Hepatic Encephalopathy
1543(7)
Hepatopulmonary Syndromes
1550(4)
Hepatorenal Syndrome
1554(4)
Endocrine Dysfunction
1558(2)
Coagulation Disorders
1560(7)
Acute Liver Failure
1567(10)
Hal F. Yee, Jr.
Steven D. Lidofsky
Definition
1567(1)
Causes
1567(2)
Clinical Presentation
1569(1)
Differential Diagnosis
1570(1)
Predictors of Outcome
1571(1)
Management
1571(6)
Hepatic Tumors and Cysts
1577(26)
Michael C. Kew
Hepatic Tumors
1577(17)
Tumor-Like Lesions
1594(1)
Hepatic Cysts
1595(3)
Approach to the Patient with Hepatic Mass Lesions
1598(5)
Hepatic Manifestations of Systemic Disease and Other Disorders of the Liver
1603(17)
Dwain L. Thiele
Hematologic Malignancies
1603(2)
Hepatic Sarcoidosis
1605(2)
Hepatic Amyloidosis
1607(3)
Sickle Cell Disease Involving the Liver
1610(2)
Hepatic Dysfunction During Systemic Infection
1612(2)
Postoperative Cholestasis
1614(1)
Liver Abnormalities in Rheumatoid Arthritis
1614(1)
Nodular Disorders of the Liver
1615(5)
Liver Transplantation
1620(23)
Paul Martin
Hugo R. Rosen
Indications
1620(2)
Listing Criteria and Policies of the United Network for Organ Sharing
1622(1)
Absolute and Relative Contraindications
1622(2)
Transplant Evaluation and Listing
1624(1)
Disease-Specific Indications
1625(5)
Surgical Aspects of Liver Transplantation
1630(2)
Immunosuppression
1632(1)
Postoperative Course
1633(2)
Long-Term Management
1635(8)
Section Ten SMALL AND LARGE INTESTINE
Anatomy, Histology, Embryology, and Developmental Anomalies of the Small and Large Intestine
1643(22)
David J. Keljo
Cheryl E. Gariepy
Intestinal Anatomy
1643(2)
Intestinal Histology
1645(3)
Embryology of the Intestine and Pathogenesis of Bowel Malformations
1648(5)
Clinical Presentations of Anomalies of the Gastrointestinal Tract
1653(1)
Associated Malformations
1654(1)
Developmental Anomalies of the Intestine
1654(11)
Small Intestinal Motor Physiology
1665(14)
Jane M. Andrews
John Dent
Major Concepts in the Evaluation of Small Intestinal Motility: Insights and Limitations of Measurements
1666(2)
Structural Elements That Determine Small Intestinal Motility
1668(4)
Control of Motor Activity
1672(1)
Clinical Measurement of Small Intestinal Motility
1673(1)
Normal Small Intestinal Motor Function in Humans
1674(2)
Clinical Consequences of Disordered Small Intestinal Motor Function
1676(1)
Approach to Patients with Possibly Disordered Small Intestinal Motor Function
1677(1)
Future Outlook
1677(2)
Motility of the Large Intestine
1679(14)
Ian J. Cook
Simon J. Brookes
Studying Colonic Motility
1679(1)
Anatomy, Innervation, and Basic Control Mechanisms
1680(4)
Relationships Among Cellular Events, Pressure, and Flow
1684(1)
Regulation of Colonic Filling, Transport, and Defecation
1684(3)
Anorectal Motility
1687(2)
Modulators of Colonic Motility
1689(1)
Disorders of Colonic Motility
1690(3)
Intestinal Electrolyte Absorption and Secretion
1693(22)
Joseph H. Sellin
Overview of Intestinal Electrolyte Traffic
1693(5)
Ion Transporters
1698(3)
Paracrine Immunoneuroendocrine Systems
1701(1)
Extracellular Regulation
1701(5)
Secretory Factors
1706(1)
Intracellular Mediators
1707(2)
Additional Regulatory Mechanisms
1709(1)
Fluid and Electrolyte Transport in Context
1710(5)
Digestion and Absorption of Nutrients and Vitamins
1715(36)
James J. Farrell
Digestion and Absorption of Nutrients
1715(2)
Digestion and Absorption of Fat
1717(6)
Carbohydrate
1723(5)
Proteins
1728(5)
Vitamins
1733(3)
Minerals and Trace Elements
1736(4)
Adaptation to Changes in Need or Load
1740(3)
The Neonatal Intestine
1743(8)
Maldigestion and Malabsorption
1751(32)
Chrisoph Hogenauer
Heinz F. Hammer
Etiology and Pathophysiology of Malabsorption Syndromes
1751(6)
Clinical Presentation and Evaluation of Malabsorption and Maldigestion
1757(2)
Anatomic Investigation
1759(4)
Noninvasive Evaluation of Gastrointestinal Absorptive and Digestive Function
1763(5)
Malabsorption in Specific Disease States
1768(9)
General Approach to the Management of Malabsorption
1777(6)
Enteric Bacterial Flora and Small Bowel Bacterial Overgrowth Syndrome
1783(11)
Clark R. Gregg
Phillip P. Toskes
Indigenous Microbial Flora of the Alimentary Tract
1783(3)
Mechanisms of Malabsorption and Diarrhea in Small Bowel Bacterial Overgrowth Syndrome
1786(8)
Irritable Bowel Syndrome
1794(13)
Nicholas W. Read
Definition and Clinical Features
1794(1)
Epidemiology
1794(2)
Pathophysiology
1796(3)
The Impact of Life Events
1799(2)
The Meaning of IBS Symptoms
1801(1)
Diagnosis
1801(1)
Treatment
1802(1)
Prognosis
1803(4)
Short Bowel Syndrome
1807(10)
Arshad Malik
Henrik Westergaard
Etiology
1807(1)
Incidence and Prevalence
1807(1)
Pathophysiology
1807(3)
Clinical Manifestations and Diagnosis
1810(1)
Management
1811(2)
Complications
1813(1)
Intestinal Transplantation
1814(1)
Newer Treatments (Growth Factors)
1814(1)
Prognosis
1814(3)
Celiac Sprue and Refractory Sprue
1817(25)
Richard J. Farrell
Ciaran P. Kelly
Definitions
1817(1)
History
1817(1)
Epidemiology
1818(1)
Pathology
1819(1)
Pathogenesis
1820(3)
Clinical Features
1823(3)
Diagnostic Studies
1826(4)
Differential Diagnosis
1830(1)
Diseases Associated with Celiac Sprue
1830(2)
Treatment
1832(2)
Complications
1834(1)
Refractory Sprue
1835(2)
Prognosis
1837(5)
Tropical Malabsorption and Tropical Diarrhea
1842(12)
Michael J. G. Farthing
Specific Causes of Tropical Malabsorption
1842(2)
Nonspecific Tropical Malabsorption
1844(1)
Tropical Enteropathy
1844(2)
Tropical Sprue
1846(8)
Whipple's Disease
1854(10)
Matthias Maiwald
Axel von Herbay
David A. Relman
History
1854(1)
Epidemiology
1854(1)
Microbiology, Immunology, and Pathogenesis
1855(1)
Clinical Manifestations
1856(1)
Pathology
1857(3)
Diagnosis
1860(1)
Differential Diagnosis
1860(1)
Treatment and Prognosis
1860(1)
Future Prospects
1861(3)
Infectious Diarrhea and Bacterial Food Poisoning
1864(50)
Davidson H. Hamer
Sherwood L. Gorbach
Changes in Normal Flora Caused by Diarrhea
1864(1)
Classifications of Bacterial Diarrhea
1865(1)
Toxigenic Diarrheas
1865(9)
Invasive Pathogens
1874(14)
Viral Diarrhea
1888(3)
Traveler's Diarrhea
1891(3)
Diarrhea in the Elderly
1894(1)
Diagnosis of Infectious Diarrheal Disease
1895(2)
Treatment of Infectious Diarrhea
1897(2)
Tuberculosis of the Gastrointestinal Tract
1899(2)
Bacterial Food Poisoning
1901(13)
Pseudomembranous Enterocolitis and Antibiotic-Associated Diarrhea
1914(19)
John G. Bartlett
Historical Perspective
1914(1)
Pathology
1915(2)
Underlying and Associated Conditions
1917(1)
Clinical Features
1917(2)
Pathophysiology
1919(2)
Diagnosis
1921(3)
Treatment
1924(3)
Prevention
1927(6)
Intestinal Protozoa
1933(18)
Christopher D. Huston
Richard L. Guerrant
Entamoeba histolytica
1933(5)
Other Intestinal Amebae
1938(1)
Giardia lamblia
1939(3)
Dientamoeba fragilis
1942(1)
Blastocystis hominis
1942(1)
Cryptosporidium parvum
1943(1)
Cyclospora cayetanensis
1944(1)
Isospora belli
1945(1)
Microsporidia
1945(1)
Trypanosoma cruzi (American Trypanosomiasis or Chagas' Disease)
1946(5)
Intestinal Infections by Parasitic Worms
1951(21)
David E. Elliott
Nematodes
1951(4)
Hookworms
1955(6)
Cestodes
1961(3)
Trematodes
1964(8)
Eosinophilic Gastroenteritis
1972(11)
Nicholas J. Talley
Definition and Incidence
1972(1)
Pathogenesis
1972(2)
Classification and Clinical Features
1974(1)
Diagnosis
1975(2)
Differential Diagnosis
1977(1)
Treatment
1978(2)
Prognosis
1980(3)
Food Allergies
1983(11)
Hugh A. Sampson
Background
1983(1)
Definitions
1983(1)
Prevalence of Food Allergy
1983(1)
Pathogenesis of Food Allergy
1983(3)
Clinical Manifestations of GI Food Allergy
1986(5)
Diagnosing Adverse Food Reactions
1991(1)
Therapy and Natural History of Food-Allergic Disorders
1991(3)
Radiation Enteritis
1994(11)
Nam P. Nguyen
John E. Antoine
Physics of Megavoltage Irradiation
1994(1)
Biologic Effects of Radiation
1994(1)
Cell Survival Curves
1995(1)
Radiosensitivity of the Cell Through Cell Cycle
1995(1)
Mechanism of Regeneration of the Intestinal Epithelium
1995(1)
Molecular Biology of Radiation Damage to the Intestinal or Colonic Mucosa
1996(1)
Incidence
1996(1)
Histopathology
1997(1)
Clinical Symptoms and Signs
1997(2)
Diagnosis
1999(1)
Management
2000(1)
Prevention
2001(4)
Crohn's Disease
2005(34)
Bruce E. Sands
History
2005(1)
Epidemiology
2005(1)
Etiology and Pathogenesis
2006(4)
Pathology
2010(1)
Clinical Manifestations
2011(6)
Differential Diagnosis
2017(1)
Establishing the Diagnosis and Evaluation of Disease
2017(5)
Treatment
2022(9)
Crohn's Disease in the Life Cycle
2031(1)
Prognosis
2032(7)
Ulcerative Colitis
2039(29)
Derek P. Jewell
History
2039(1)
Epidemiology
2040(1)
Genetics
2040(1)
Etiology
2041(1)
Immunopathogenesis
2042(2)
Psychosomatic Aspects
2044(1)
Pathology
2044(2)
Clinical Features
2046(1)
Assessment of Disease Severity
2047(1)
Diagnosis
2048(4)
Differential Diagnosis
2052(2)
Extraintestinal Manifestations
2054(1)
Medical Management
2055(4)
Treatment Regimens
2059(2)
Local Complications
2061(2)
Indications for Surgery and Choice of Operation
2063(1)
Course and Prognosis
2063(1)
Ulcerative Colitis in Pregnancy
2064(1)
Ulcerative Colitis in Childhood
2064(4)
Ileostomy and Its Alternatives
2068(13)
John H. Pemberton
Sidney F. Phillips
Pathophysiologic Consequences of Proctocolectomy
2069(1)
Overall Clinical Consequences of Proctocolectomy
2069(1)
Complications and Management of Conventional Ileostomies
2070(1)
Continent Ileostomy (Kock Pouch)
2070(1)
Ileal Pouch-Anal Anastomosis
2071(4)
Abdominal Colectomy and Ileorectal Anastomosis
2075(1)
Colostomy in the Management of Inflammatory Bowel Disease
2076(1)
Summary of Risk-Benefit Analysis
2076(5)
Isolated and Diffuse Ulcers of the Small Intestine
2081(8)
Deborah D. Proctor
Lisa Ann Panzini
Isolated Ulcers
2081(3)
Diffuse Ulcerations
2084(5)
Appendicitis
2089(11)
George A. Sarosi, Jr.
Richard H. Turnage
Historical Perspective
2089(1)
Epidemiology
2089(1)
Anatomy and Embryology
2089(1)
Pathology
2090(1)
Pathogenesis
2090(1)
Diagnosis
2091(3)
Diagnostic Accuracy
2094(1)
Complications
2095(1)
Treatment
2096(1)
Treatment Outcomes
2097(1)
Miscellaneous Topics
2097(3)
Diverticular Disease of the Colon
2100(13)
Clifford L. Simmang
G. Thomas Shires III
Diverticulosis
2102(2)
Diverticular Bleeding
2104(2)
Diverticulitis
2106(7)
Intestinal Obstruction and Ileus
2113(16)
Richard H. Turnage
Patricia Bergen
Definitions
2113(1)
Small Intestinal Obstruction
2113(2)
Clinical Presentation
2115(1)
Radiologic Findings
2116(1)
Laboratory Findings
2117(1)
Treatment and Outcome
2117(2)
Special Considerations
2119(2)
Colonic Obstruction
2121(4)
Ileus
2125(4)
Megacolon: Congenital and Acquired
2129(11)
Elizabeth J. McConnell
John H. Pemberton
Classification of Megacolon
2129(1)
Pathophysiology of Colonic Dilatation
2129(2)
Hirschsprung's Disease: Congenital Megacolon
2131(4)
Variants of Congenital Megacolon
2135(1)
Acquired Megacolon and Megarectum
2135(2)
Acute Megacolon
2137(3)
Chronic Intestinal Pseudo-Obstruction
2140(11)
Michael D. Schuffler
Causes and Pathology
2140(2)
Clinical Manifestations
2142(1)
Laboratory Findings
2142(1)
Radiographic Findings
2143(1)
Manometric Abnormalities
2144(1)
Examples of Specific Syndromes
2145(1)
Diagnosis
2146(2)
Treatment
2148(1)
Prognosis
2149(2)
Gastrointestinal Carcinoid Tumors and the Carcinoid Syndrome
2151(18)
Thomas Anthony
Lawrence Kim
Clinical Presentation
2152(1)
Pathology
2152(1)
Classification
2152(4)
Metastatic Carcinoid and Carcinoid Syndrome
2156(3)
Metastatic Carcinoid Tumors
2159(10)
Small Intestinal Neoplasms
2169(6)
Anil K. Rustgi
Epidemiology
2169(1)
Pathology
2169(1)
Etiology and Risk Factors
2170(1)
Clinical Presentation
2171(1)
Diagnosis
2171(1)
Management
2172(3)
Colonic Polyps and Polyposis Syndromes
2175(40)
Steven H. Itzkowitz
Colonic Polyps
2175(21)
Gastrointestinal Polyposis Syndromes
2196(19)
Malignant Neoplasms of the Large Intestine
2215(48)
Robert S. Bresalier
Descriptive Epidemiology and Epidemiologic Patterns
2215(2)
Theories and Clues About Causation
2217(5)
Biology of Colorectal Cancer
2222(5)
Familial Colon Cancer
2227(2)
Predisposition to Colorectal Cancer
2229(3)
Tumor Pathology, Natural History, and Staging
2232(3)
Prognostic Indicators
2235(5)
Clinical Presentations
2240(1)
Diagnosis and Screening
2241(9)
Treatment
2250(6)
Other Malignant Large Bowel Tumors
2256(7)
Proctitis and Sexually Transmissible Intestinal Disease
2263(14)
Ronald Fried
Christina Surawicz
Clinical Syndromes
2263(3)
Diagnosis
2266(1)
Specific Diseases
2266(11)
Examination and Diseases of the Anorectum
2277(17)
Tracy Hull
Anatomy
2277(1)
Examination of the Anus and Rectum
2278(2)
Hemorrhoids
2280(2)
Anal Fissure
2282(2)
Anal Sepsis---Abscesses and Fistulas
2284(2)
Special Fistulas
2286(1)
Anal Cancer
2287(1)
Anal Warts
2287(1)
Pruritus Ani
2288(1)
Anal Stenosis
2289(1)
Unexplained Anal Pain
2289(1)
Hidradenitis Suppurativa
2290(1)
Pilonidal Disease
2290(1)
Rectal Foreign Body
2291(3)
Other Diseases of the Colon and Rectum
2294(27)
David Blumberg
Arnold Wald
Rectal Prolapse
2294(2)
Solitary Rectal Ulcer Syndrome
2296(2)
Nonspecific Colonic Ulcers
2298(1)
Dieulafoy-Type Colonic Ulceration
2299(1)
Stercoral Ulcer
2299(1)
Lymphocytic and Collagenous Colitis
2300(3)
Diversion Colitis
2303(1)
Cathartic Colon
2304(1)
(Pseudo)Melanosis Coli
2305(1)
Chemical Colitis
2305(1)
Malakoplakia
2306(1)
Pneumatosis Coli (Pneumatosis Cystoides Intestinalis)
2307(2)
Colitis Cystica Profunda
2309(1)
Neutropenic Enterocolitis (Typhlitis)
2310(1)
Endometriosis
2311(10)
Section Eleven VASCULATURE AND SUPPORTING STRUCTURES
Intestinal Ischemia
2321(20)
Lawrence J. Brandt
Scott J. Boley
Anatomy of the Splanchnic Circulation
2321(1)
Pathophysiology and Pathology of Mesenteric Ischemia
2322(1)
Acute Mesenteric Ischemia
2323(6)
Mesenteric Venous Thrombosis
2329(2)
Focal Segmental Ischemia of the Small Bowel
2331(1)
Colonic Ischemia
2331(5)
Chronic Mesenteric Ischemia (Intestinal Angina)
2336(1)
Vasculitis of the Splanchnic Circulation
2337(4)
Vascular Lesions of the Gastrointestinal Tract
2341(16)
David A. Greenwald
Lawrence J. Brandt
Vascular Lesions
2341(10)
Abdominal Aortic Aneurysm
2351(1)
Paraprosthetic Enteric and Aortoenteric Fistula
2352(1)
Superior Mesenteric Artery Syndrome
2352(1)
Celiac Axis Compression Syndrome (CACS)
2353(4)
Surgical Peritonitis and Other Diseases of the Peritoneum, Mesentery, Omentum, and Diaphragm
2357(14)
Bruce A. Runyon
Jose Such
Anatomy and Physiology
2357(1)
Surgical Peritonitis
2358(3)
Peritonitis of Other Causes
2361(2)
Peritoneal Tumors
2363(2)
Diseases of the Mesentery and Omentum
2365(2)
Diseases of the Diaphragm
2367(1)
Laparoscopy in the Evaluation of Peritoneal Diseases
2367(4)
Section Twelve PSYCHOSOCIAL FACTORS IN GASTROINTESTINAL DISEASE
A Biopsychosocial Understanding of Gastrointestinal Illness and Disease
2371(9)
Douglas A. Drossman
A Conceptualization
2371(4)
Early Life
2375(1)
Psychosocial Environment
2376(2)
Central and Enteric Nervous Systems: The Brain-Gut Axis
2378(2)
Symptom Experience and Behavior
2380(1)
Outcome
2380(1)
Clinical Applications
2380
Index 1

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