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Atlas of Diagnostic Cytopathology

Author(s): Atkinson
Edition: 2nd
ISBN10: 0721600638
ISBN13: 9780721600635
Cover: Hardcover
 
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SummaryTable of Contents
The New Edition of the field's standard sourcebook delivers thoroughly revised and up-to-date coverage of aspiration and exfoliative cytology and its impact on the practice of anatomic pathology today. Over 1,700 all-new, full-color illustrations capture the appearance of a complete range of cytopathology specimens, their histologic correlations, and the results of relevant ancillary studies. Each chapter discusses the challenges of that specimen site; describes the diagnostic criteria and differential diagnosis; and explains how the diagnosis is reached.

  • Presents comprehensive, pictorial coverage of the cytopathology of every organ system.
  • Includes diagnostic rules and tips.
  • Discusses medical liability and the practice of cytopathology.
  • Highlights key information in tables and boxes.


  • Reflects all of the changes in both aspiration and exfoliative cytology, and discusses the utility of different cytologic stains in detail.
  • Features an expanded section on gynecologic cytopathology that includes the diagnostic criteria for breast cancer and the associated diagnostic applications.
  • Discusses new pathologic entities and the Betheseda System of Nomenclature for interpreting Pap tests.
  • Covers ancillary techniques of diagnostic cytopathology
  • Addresses ethical and medicological issues in new chapters.
  • Offers over 1,700 all-new, full-color illustrations that clearly demonstrate procedures as well as more Diff Quik stains for fine needle aspirates.
  • Includes true histologic correlations and discusses the role of all ancillary tests.
1 General Cytologic Principles 1(30)
Elizabeth T. McKinley
Clinical History and Pathologic Correlations
2(1)
Adequacy: Hitting the Target
3(2)
Background
5(7)
Tables start on page
12(1)
Figures start on page
13(18)
2 Gynecologic Cytopathology 31(74)
Marianne U. Prey and Fadi Abdul-Karim
History of Cervical Cytology
32(1)
Biology of Cervical Neoplasia
32(1)
Cervical Cancer Screening
33(2)
Cytologic Interpretation
35(13)
Tables start on page
48(2)
Figures start on page
50(55)
3 Effusions (Pleural, Pericardial, and Peritoneal) and Peritoneal Washing Cytopathology 105(46)
Lisa L. Weinstein and Edmund S. Cibas
General Principles
106(1)
Benign Elements
107(1)
Non-Neoplastic Conditions
108(1)
Malignant Effusions
108(7)
Peritoneal Washings
115(2)
Tables start on page
117(1)
Figures start on page
118(33)
4 Cerebrospinal Fluid and Brain Cytopathology 151(48)
Pascale Hummel Levine and David Zagzag
Cytopathology of the Central Nervous System
152(3)
Cytopathology of Cerebrospinal Fluid
155(4)
Conclusion
159(2)
Figures start on page
161(38)
5 Gastrointestinal Tract Cytopathology 199(32)
Nirag Jhala and Darshana Jhala
Sample Types and Preparation
200(1)
Normal Cytology
201(2)
Infections
203(2)
Reactive/Inflammatory Processes and Other Non-Neoplastic Lesions
205(2)
Preneoplastic Conditions
207(1)
Neoplasms
208(7)
Tables start on page
215(1)
Figures start on page
216(15)
6 Urinary Tract Cytopathology 231(42)
Chris S. Jensen and Michael B. Cohen
Collection and Processing of Urinary Cytology Samples
232(1)
Histology and Cytology of the Normal Urinary Tract
233(2)
Urothelial Carcinoma
235(4)
Other Urinary Tract Malignancies
239(2)
Mimics of Carcinoma in Urinary Cytology
241(4)
Other Inflammatory Conditions
245(1)
Conclusion
246(2)
Tables start on page
248(3)
Figures start on page
251(22)
7 Respiratory Tract Cytopathology 273(84)
Vinod B. Shidham
Anatomy
274(1)
Background
274(1)
Exfoliative Pulmonary Cytology
275(10)
Fine-Needle Aspiration Cytology of Lung
285(17)
Pitfalls in Respiratory Cytopathology
302(5)
Tables start on page
307(21)
Figures start on page
328(29)
8 Aspiration of the Breast 357(34)
Patricia A. Thomas and Fang Fan
Benign Lesions
359(2)
Benign Tumors
361(1)
Inflammatory Lesions
362(1)
Pregnancy-Related and Focal Secretory Changes
363(1)
Malignant Lesions
363(1)
Miscellaneous
364(1)
Male Breast
365(1)
Other Sources of Breast Cytology
365(1)
"Thomas's Tips"
366(2)
Tables start on page
368(2)
Figures start on page
370(21)
9 Aspiration of the Mediastinum 391(20)
Celeste N. Powers and Kristen A. Atkins
Non-Neoplastic Lesions
392(1)
Thymoma
393(1)
Lymphoproliferative Lesions
394(1)
Germ Cell Tumors
395(1)
Neural Tumors
396(1)
Metastatic Disease
397(1)
Tables start on page
398(1)
Figures start on page
399(12)
10 Aspiration and Touch Preparation of Lymph Nodes 411(48)
Paul E. Wakely, Jr.
Non-Neoplastic Lymphadenopathy
413(6)
Neoplastic Lymphadenopathy
419(10)
Tables start on page
429(4)
Figures start on page
433(26)
11 Aspiration of the Thyroid 459(38)
William C. Faquin
Indications and Sampling
460(2)
Thyroiditis
462(2)
Other Benign Conditions
464(1)
FNA as a Screening Test: Follicular and Oncocytic Lesions
464(2)
FNA as a Diagnostic Test: Papillary Thyroid Carcinoma
466(5)
Tables start on page
471(2)
Figures start on page
473(24)
12 Aspiration of the Salivary Glands 497(30)
Kristen A. Atkins and Celeste N. Powers
Normal Salivary Glands
498(1)
Reactive Lesions
499(1)
Cysts
500(1)
Benign Neoplasms
500(3)
Malignant Neoplasms
503(5)
Figures start on page
508(19)
13 Aspiration of Cutaneous and Miscellaneous Lesions of the Head and Neck 527(24)
Kristen A. Atkins and Celeste N. Powers
Benign Cysts
528(1)
Benign Cutaneous and Subcutaneous Lesions
529(3)
Malignant Cutaneous Lesions
532(2)
Miscellaneous
534(2)
Figures start on page
536(15)
14 Aspiration of Liver and Pancreas 551(54)
Martha Bishop Pitman and Barbara A. Centeno
Techniques
552(1)
Specimen Preparation
552(1)
Liver
553(7)
Pancreas
560(10)
Tables start on page
570(5)
Figures start on page
575(30)
15 Aspiration of the Kidney, Adrenal Gland, and Retroperitoneum 605(22)
Barbara S. Ducatman
General Guidelines
606(1)
Benign Diseases
606(2)
Malignant Tumors
608(3)
Retroperitoneum
611(1)
Small Blue Cell Tumors of Childhood
611(2)
Figures start on page
613(14)
16 Aspiration of Soft Tissue and Bone 627(36)
Harsharan K. Singh, Scott E. Kilpatrick, and Jan F. Silverman
Diagnostic Approach
628(1)
Technical Considerations
629(1)
Fine-Needle Aspiration Biopsy of Soft Tissue
630(10)
Fine-Needle Aspiration Biopsy of Bone
640(6)
Conclusion
646(3)
Tables start on page
649(3)
Figures start on page
652(11)
17 Aspiration of the Ovary 663(22)
Suzanne M. Selvaggi
Technique
664(1)
Normal Cellular Constituents
664(1)
Non-Neoplastic Ovarian Cysts
665(1)
Neoplastic Cystic Ovarian Lesions
666(2)
Metastatic Tumors
668(1)
Diagnostic Pitfalls and Ancillary Techniques
669(1)
Detection Rate of Ovarian Lesion by Aspiration Cytology
669(2)
Tables start on page
671(2)
Figures start on page
673(12)
18 Ocular Cytopathology 685(20)
Robert Folberg and Narsing A. Rao
Conjunctival Cytology
687(1)
Corneal Cytology
687(1)
Anterior Chamber Fluid Aspirates
688(3)
Vitreous Cytology
691(3)
Fine-Needle Biopsies: Intraocular Tumors
694(2)
Conclusion
696(2)
Figures start on page
698(7)
19 Cytopathology of the Orbit, Ocular Adnexa, and Eyelid 705(16)
Charles D. Sturgis and Jan F. Silverman
Hematolymphoid Proliferations
707(1)
Orbital Mesenchymal Neoplasms
708(1)
Solid Tumors Directly Invading or Metastasizing to the Orbit
708(1)
Primary Neop4asms of the Lacrimal Glands
709(1)
Tumors of the Eyelids
710(2)
Figures start on page
712(9)
20 Pediatric Cytopathology 721(26)
Lydia Pleotis Howell
Round Cell Lesions
723(2)
Inflammatory Lesions
725(1)
Spindle Cell Lesions
726(1)
Epithelial/Epithelioid
727(2)
Tables start on page
729(6)
Figures start on page
735(12)
21 Ancillary Techniques in Cytopathology 747(60)
Patricia A. Fetscb and Andrea Abati
Immunocytochemistry
748(8)
Electron Microscopy
756(1)
Fluorescent Techniques
757(2)
Molecular Techniques
759(2)
Cellular Image Analysis
761(1)
Immunomagnetic Bead Techniques
762(1)
Proteomics:TheNewFrontier?
763(5)
Tables start on page
768(8)
Figures start on page
776(31)
22 Medical Liability and the Practice of Cytopathology 807(34)
William J. Frable
Gynecologic Cytopathology
808(8)
Nongynecologic Cytopathology: Fine Needle Aspiration
816(5)
Conclusion
821(3)
Tables start on page
824(1)
Figures start on page
825(16)
Index 841

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