Blood Science Principles and Pathology

The second edition of the leading introduction to blood science, with updated new illustrations and case studies

Blood Science: Principles and Pathology integrates hematology and blood transfusion, ­clinical biochemistry, and immunology to provide a thorough introduction to this rapidly expanding discipline. Reflecting recent changes in education and training for healthcare scientists, this comprehensive textbook covers the analytical techniques used in blood ­science, the diagnosis and management of various blood disorders, and more.

Fully revised, the second edition presents new case studies and high-quality images ­throughout, illustrating the practical skills and knowledge required by today’s under­graduate students and practitioners. Detailed yet accessible chapters contain learning objectives and summaries, links to further readings and resources, and real-world case studies with easy-to-follow interpretations. Throughout the text, the authors highlight how laboratory data and clinical details are used to investigate patients with actual or suspected diseases in real-world scenarios:

• Multi-disciplinary view merging biochemical, hematological, immunological, and genetical knowledge into a single discipline: Blood science
• Discusses advances in molecular genetics identifying mutations resulting in the occurrence of certain pathological conditions such as leukaemia
• Presents an expanded concluding chapter with detailed case reports that integrate biochemistry, immunology, and haematology, which all contribute to the investigation of respective conditions
• Explains the potentials for developing tests such as non-coding RNAs
• Offers further reading suggestions to dive even deeper into discussed subjects and concepts

Designed to meet the needs of undergraduate students taking blood science modules in biomedical, biological, and healthcare science programs, Blood Science: Principles and Pathology, Second Edition is also an invaluable guide for new graduates entering the field, as well as those training for professional qualifications or working with blood samples in laboratory-based environments.

Dr Andrew Blann, Consultant Clinical Scientist, The Institute of Biomedical Science, ­London, UK.

Dr Nessar Ahmed, Reader in Clinical Biochemistry, Department of Life Sciences, ­Manchester Metropolitan University, UK.

Preface

Acknowledgements

List of Abbreviations

About the Companion Website

1. Introduction to Blood Science

2. Analytical Techniques in Blood Science

3. The Physiology of the Red Blood Cell

4. The Pathology of the Red Blood Cell

5. White Blood Cells in Health and Disease

6. White Blood Cell Malignancy

7. The Physiology and Pathology of Haemostasis

8. The Diagnosis and Management of Disorders of Haemostasis

9. Immunopathology

10. Immunogenetics and Histocompatibility

11. Blood Transfusion

12. Waste products, electrolytes, and renal disease

13. Hydrogen ions, pH, and acid-base disorders

14. Glucose, lipids, and atherosclerosis

15. Calcium, phosphate, magnesium, and bone disease

16. Nutrients and Gastrointestinal Disorders

17. Liver function tests and plasma proteins

18. Endocrinology

19. Cancer and tumour markers

20. Inherited Metabolic Disorders

21. Drugs and Poisons

22. Case Reports in Blood Science

Further Reading

Appendix 1: Reference Ranges

Glossary

Index

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