| Preface to the Second Edition |
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| Preface to the First Edition |
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vii | |
| Contributors |
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xiii | |
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3 | (4) |
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Overview of Epidemiology and Genetics |
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7 | (4) |
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OPLL: Disease Entity, Incidence, Literature Search, and Prognosis |
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11 | (8) |
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Genetic Susceptibility to OPLL |
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19 | (10) |
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Pathology and Pathogenesis |
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Overview of Etiology and Pathogenesis |
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29 | (4) |
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Etiology and Pathogenesis |
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33 | (4) |
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Contribution of Metabolic Conditions to Ossification of the Posterior Longitudinal Ligament of the Spine |
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37 | (4) |
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Review of Histopathological Studies on OPLL of the Cervical Spine, with Insights into the Mechanism |
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41 | (8) |
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Pathology of Ossification of the Ligamentum Flavum |
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49 | (10) |
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Possible Roles of Bone Morphogenetic Proteins and Transforming Growth Factor-βs in the Pathogenesis of OPLL and OLF |
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59 | (6) |
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Pathology of Spinal Cord Lesions Caused by Ossification of the Posterior Longitudinal Ligament |
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65 | (6) |
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Tiptoe Walking (ttw) Mouse |
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71 | (6) |
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Study of Ligament Ossification and Abnormal Glucose Tolerance in the Zucker Fatty Rat |
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77 | (16) |
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Experimental Murine Model of Ossification of Spinal Ligaments Induced by Bone Morphogenetic Protein-2 |
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93 | (8) |
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Spinal Cord Lesions in Spinal Hyperostotic Mouse (twy/twy) Simulating Ossification of the Posterior Longitudinal Ligament of the Cervical Spine |
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101 | (10) |
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Diagnosis of OPLL and OYL |
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Diagnosis of OPLL and OYL: Overview |
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111 | (4) |
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Clinical Manifestation of Cervical OPLL |
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115 | (6) |
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Clinical Manifestations of Thoracic OPLL and OLF |
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121 | (6) |
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Diagnostic Imaging of Cervical Ossification of the Posterior Longitudinal Ligament |
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127 | (18) |
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Imaging Diagnosis of Thoracic OPLL and OLF |
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145 | (6) |
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Electrophysiological Diagnosis of Cervical OPLL Myelopathy |
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151 | (14) |
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Treatment of OPLL and OLF |
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Overview of Treatment for Ossification of the Longitudinal Ligament and the Ligamentum Flavum |
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165 | (4) |
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Pharmacotherapy for Ossification of the Spinal Ligaments: Clinical Trial of Disodium (1-Hydroxyethylidene) Diphosphonate to Inhibit Progression of Ossification of the Posterior Longitudinal Ligament in the Cervical Spine after Posterior Decompression Surgery |
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169 | (8) |
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Conservative Treatment of Ossification of the Posterior Longitudinal Ligament in the Cervical Spine |
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177 | (4) |
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Choice of Surgical Procedure |
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181 | (6) |
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187 | (6) |
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Expansive Open-door Laminoplasty for Ossification of the Posterior Longitudinal Ligament of the Cervical Spine: Surgical Indications, Technique, and Outcomes |
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193 | (8) |
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Double-door Laminoplasty by Splitting Spinous Processes |
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201 | (8) |
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Anterior Cervical Decompression for Cervical Myelopathy Caused by Ossification of the Posterior Longitudinal Ligament |
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209 | (10) |
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Treatment of OPLL and OLF of the Cervical Spine: Long-Term Results |
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219 | (6) |
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Choice of Surgical Procedures for Thoracic Ossification of the Posterior Longitudinal Ligament |
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225 | (6) |
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Anterior Decompression and Fusion for Ossification of the Posterior Longitudinal Ligament of the Thoracic Spine: Procedure and Clinical Outcomes of Transthoracic and Transsternal Approaches |
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231 | (4) |
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Circumspinal Decompression with Dekyphosis Stabilization for Thoracic Myelopathy due to Ossification of the Posterior Longitudinal Ligament |
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235 | (6) |
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Posterior Extensive Cervicothoracic Laminoplasty |
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241 | (8) |
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Anterior Decompression Through Posterior Approach for Thoracic Myelopathy Caused by OPLL: Ohtsuka Procedure |
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249 | (10) |
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Surgical Treatment for Ossification of the Posterior Longitudinal Ligament of the Thoracic Spine: Outcomes of One-Stage Posterior Decompression with Corrective Fusion Surgery |
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259 | (6) |
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Surgery for Ossification of the Ligamentum Flavum |
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265 | (6) |
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Computer-Aided Surgery for Ossification of the Spinal Ligaments |
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271 | (8) |
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Surgical Treatment of Thoracic Ossification of the Posterior Longitudinal Ligament: Intraoperative Spinal Cord Monitoring |
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279 | (8) |
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Intraoperative Ultrasonography for Patients with Ossification of the Posterior Longitudinal Ligament |
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287 | (12) |
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| Appendix: Diagnostic Criteria for OPLL and Diagnosis and Treatment Algorithm |
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299 | (4) |
| Subject Index |
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303 | |
