| Preface |
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V | |
| Application to Cancer Prevention |
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3 | (52) |
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Diet and Cancer: Epidemiological Approaches |
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3 | (6) |
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Mechanisms of Chronic Disease Prevention |
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9 | (5) |
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Epidemiology of Vegetables and Fruits in Cancer Prevention |
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14 | (7) |
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Antimutagenesis and Cancer Prevention |
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21 | (5) |
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Multiple Mechanisms of Cancer Prevention by Phytochemicals: Interaction Between Cellular Proliferation and Endogenous Mutagens |
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26 | (4) |
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Diet and Cancer Prevention in the United States |
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30 | (6) |
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Biochemoprevention: A New Concept for Cancer Control |
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36 | (3) |
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Biochemical and Physiological Importance of Plant Polyphenols |
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39 | (8) |
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Studies on Functional Foods in Japan: State of the Art |
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47 | (8) |
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| Carcinogenesis and Its Inhibition: Experimental Approaches |
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55 | (50) |
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Free Radicals, Antioxidants, and Cancer |
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55 | (3) |
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Increased 8-Hydroxyguanine Repair Activity in Animal Livers and Human Leukocytes Induced by Oxidative Stress: Effects of Diet, Physical Exercise, and Cigarette Smoking |
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58 | (5) |
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Effects of Aging and Vitamin a Deficiency on DNA Damage |
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63 | (4) |
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Use of Mouse JB6 Cells to Identify Molecular Targets and Novel Agents for Prevention of Carcinogenesis |
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67 | (10) |
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Tumor Progression Accelerated by Oxygen Species and Its Chemoprevention |
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77 | (5) |
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Prevention of Chemically Induced Rat Carcinogenesis by Antioxidants: Focus on HTHQ |
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82 | (6) |
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Development of Medium-Term Bioassays for Detection of Chemopreventive Agents |
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88 | (4) |
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Preventive Effects of Various Antioxidants on Endogenous Liver Carcinogenesis in Rats Fed a Choline-Deficient, L-Amino Acid-Defined Diet |
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92 | (6) |
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Protective Role of Dietary Factors in Carcinogenesis of Digestive Organs |
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98 | (7) |
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| Green Tea |
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105 | (54) |
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Epidemiological Evidence for Prevention of Cancer and Cardiovascular Disease by Drinking Green Tea |
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105 | (4) |
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Tea Components and Cancer Prevention |
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109 | (4) |
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Mechanistic Considerations of the Inhibition of Carcinogenesis by Tea |
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113 | (5) |
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Inhibitory Effects and Toxicity of Green Tea Components for the Prevention of Gastrointestinal Carcinogenesis |
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118 | (4) |
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Anticarcinogenesis of Tea Polyphenols |
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122 | (5) |
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Mechanism of (-)-Epigallocatechin Gallate and Green Tea in Inhibition of Carcinogenesis |
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127 | (3) |
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Tea as Antioxidant in Prevention of Lung Cancer |
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130 | (4) |
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Inhibitory Effects of Green Tea Infusion on In Vitro Invasion and In Vivo Metastasis of Mouse Lung Carcinoma Cells |
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134 | (4) |
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Antitumor-Promoting Effects of Tea Aqueous Nondialysates in Mouse Epidermal JB6 Cells |
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138 | (4) |
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Inhibitory Effects of Tea Extracts on the Formation of Heterocyclic Amines During Cooking of Hamburger |
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142 | (5) |
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Prophylactic Functions of Antioxidant Tea Polyphenols |
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147 | (5) |
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Antioxidative Activity Against Superoxide of Anticarcinogenic Tea-Leaf Catechins: Measurement by the Cypridina Chemiluminescence Method |
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152 | (7) |
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| Fruit and Vegetables |
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159 | (56) |
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Stimulation of Leukocytes by Vegetable and Fruit Juices |
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159 | (3) |
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Formation of Thioproline, Effective as a Nitrite-Trapping Agent in the Human Body, in Various Cooked Foods |
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162 | (4) |
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Antimutagen Formation and Nitrite Scavenging by Unprocessed or Processed Fruit and Vegetable Fibers |
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166 | (4) |
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Anticancer Functions of Nondialyzable Extracts of Vegetables and Fruits |
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170 | (4) |
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Spinach Induces the Differentiation of Human Leukemia Cells |
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174 | (4) |
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Effects of Apple Pectin on Fecal Enzyme Activities and Prostaglandin E(2) Levels in Azoxymethane-induced Rat Colon Carcinogenesis |
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178 | (4) |
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Some Phytochemicals and Related Compounds in Vegetables as Potent Inhibitors of Human DNA Topoisomerase II |
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182 | (6) |
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Anti-tumor Promoters from Edible Thai Plants: Isolation, Cancer Preventive Potential, and Action Mechanisms |
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188 | (6) |
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Chemoprevention of Oral and Colon Carcinogenesis by Natural Compounds Protocatechuic Acid, l'-Acetoxychavicol Acetate, S-Methyl Methane Thiosulfonate, and Hesperidin from Vegetables and Fruits |
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194 | (6) |
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Enhancement by Indole-3-Carbinol of Liver and Thyroid Gland Neoplastic Development in a Rat Medium-Term Multiorgan Carcinogenesis Model |
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200 | (4) |
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Distribution of Carotenoids in Fruits and Vegetables as a Criterion for the Selection of Appropriate Chemopreventive Agents |
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204 | (5) |
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The Tomato Carotenoid Lycopene and Cancer |
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209 | (6) |
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| Spices |
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215 | (50) |
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rganoselenium and Organosulfur Phytochemicals from Genus Allium Plants (Onion, Garlic): Relevance for Cancer Protection |
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215 | (7) |
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The Role of Flavonoids and Garlic in Cancer Prevention |
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222 | (4) |
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Garlic Reduces Plasma Cholesterol in Hypercholesterolemic Men Maintaining Habitual Diets |
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226 | (5) |
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Inhibition Site of Methylallyl Trisulfide, a Volatile Oil Component of Garlic, in the Platelet Arachidonic Acid Cascade |
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231 | (4) |
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Antitumor-Promoting Activities of Ginsenoside Rg(1) and Panax notoginseng |
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235 | (5) |
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Preventive Effects of Panax ginseng C. A. Meyer on Various Human Cancers |
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240 | (5) |
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Sesamin, a Multifunctional Factor for Prevention of Various Disorders Including Carcinogenesis |
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245 | (4) |
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Antioxidant and Antitumorigenic Properties of Curcumin |
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249 | (4) |
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Antitumorigenic Activity of Rosemary |
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253 | (4) |
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Effects of Capsaicin, a Major Pungent Principle in Hot Red Pepper, on Chemically Induced Carcinogenesis and Mutagenesis |
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257 | (8) |
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| Herbs |
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265 | (28) |
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Antitumor Promoters from Plants Used as Condiments or Garnishes |
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265 | (5) |
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Cancer Chemoprevention with Everyday Food, Traditional Japanese Food, and Traditional Folk Medicines |
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270 | (6) |
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Bioactive Phenolic Compounds for Cancer Prevention from Herbal Medicines |
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276 | (4) |
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Structure-Activity Relationship of Antioxidant and Antitumor Polyphenols |
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280 | (6) |
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Abrus (A. precatorius L.) Leaf Extract as a Novel Antitumor Agent |
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286 | (7) |
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| Cereals and Beans |
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293 | (38) |
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Antioxidative Defense System and Free Radical Scavenging Potentials of Cereals |
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293 | (6) |
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Natural Antioxidants from Oilseeds |
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299 | (5) |
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A Strong Antioxidant Found in Young Green Barley Leaves |
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304 | (5) |
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Antioxidative and Antigenotoxic Properties of Flavonoids from Beans (Phaseolus vulgaris L.) |
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309 | (4) |
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Photon Emission by Natural Radical Scavengers in the Presence of Active Oxygen Species |
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313 | (5) |
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Inhibition of Lipid Peroxidation and Radical Scavenging Effect of Anthocyanin Pigments Isolated from the Seeds of Phaseolus vulgaris L. |
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318 | (5) |
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Triterpene Saponins from Vigna unguiculata, Phaseolus vulgaris, Phaseolus coccineus, Canavalia gladiata, and Lupinus polyphyllus x arboreus: Their Structures, Antihepatotoxic Activities, and Antioxidative Inactivity |
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323 | (8) |
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| Marine Products |
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331 | (20) |
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Antitumor Peptidoglycan with New Carbohydrate Structure from Squid Ink |
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331 | (6) |
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Dietary Marine Algae and Their Antitumor Effects |
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337 | (5) |
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Antimutagenic, Antiinflammatory, and Potential Anticancer Substances from Marine Algae |
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342 | (9) |
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| Processed Foods |
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351 | (32) |
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Effects of Miso in Reducing Risk of Liver and Gastric Tumors in Experimental Animals |
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351 | (4) |
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Food Factors from Fermented Foods: Isolation of Monascin, Ankaflavin, and Kojic Acid as Lipoxygenase Inhibitors from Beni-Koji and Koji |
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355 | (4) |
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Superoxide Radical Scavenging Activities of Wines, and Antioxidative Properties of Fractions Recovered from Merlot Wine Pomace |
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359 | (6) |
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Conjugated Linoleic Acid: An Anticarcinogenic Nutrient |
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365 | (2) |
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Intestinal Flora and Cancer Control: Inhibitory Effect of Oral Administration of Lactobacillus casei in a Model of Hepatic Metastasis of Rat |
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367 | (4) |
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Prophylactic Effect of a Lactobacillus casei Preparation on the Recurrence of Bladder Cancer |
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371 | (4) |
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Free Radical-Scavenging Effect of a Designed Antioxidant Drink: An Electron Spin Resonance Study |
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375 | (8) |
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| Minerals |
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383 | (28) |
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Dynamics of Trace Elements and Metal-Dependent Enzymes in Stomach Cancer Patients |
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383 | (6) |
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Stomach Cancer and Mineral Intake |
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389 | (7) |
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Chemopreventive Effects of Magnesium Hydroxide on Colon Carcinogenesis |
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396 | (5) |
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Dietary Calcium and Vitamin D as Inhibitors of Colon and Breast Carcinogenesis |
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401 | (10) |
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| Vitamin C |
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411 | (20) |
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A New Approach to the Treatment of Atopic Dermatitis: Antioxidant Vitamins and Atopic Dermatitis |
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411 | (4) |
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Effect of Dietary Paraquat on a Rat Mutant Unable to Synthesize Vitamin C |
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415 | (3) |
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Role of Supplemental Ascorbate on Regulation of Growth in Cultured Cells |
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418 | (3) |
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Physiological Role of Ascorbic Acid in Xenobiotic Metabolism and Protection Against Oxidative Stress |
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421 | (3) |
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Biological Antioxidants Under Oxidative Stress |
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424 | (7) |
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| Vitamin E |
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431 | (60) |
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Vitamin E and Cancer Prevention: Methodological Aspects of Human Studies |
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431 | (5) |
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Inhibitory Effect of Vitamin E on Cellular Events Related to Lung Tumorigenesis in Mice |
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436 | (4) |
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Prevention of Breast Cancer in Acatalasemic Mice by Vitamin E Supplementation |
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440 | (4) |
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Protective Role of Vitamin E on Iron-Induced Nephrotoxicity and Carcinogenesis: A Model of Free Radical Pathology |
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444 | (4) |
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Evaluation of Oxidative Stress due to X-Irradiation: In Vivo ESR Studies |
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448 | (4) |
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Vitamin E and the Antioxidant Network: Protection of Human Low Density Lipoprotein from Oxidation |
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452 | (8) |
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Macrophages and Vitamin E |
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460 | (5) |
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Effect of Alpha-Tocopherol on Expression of Intercellular Adhesion Molecule-1 and Vascular Adhesion Molecule-1 on Human Vascular Endothelial Cells |
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465 | (3) |
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Effects of Natural Antioxidants on the Activation of Transcription Factor NF-kB and p53 |
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468 | (4) |
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Distribution and Biodiscrimination of Alpha-Tocopherol Stereoisomers |
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472 | (7) |
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Scavenging of Singlet Oxygen by Alpha-Tocopherol in Liposomes |
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479 | (4) |
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Free Radical-Scavenging Reactions of Alpha-Tocopherol During the Peroxidation of Unsaturated Lipids |
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483 | (8) |
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| Lipids |
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491 | (24) |
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Dietary Polyunsaturated Fatty Acids and Cancer: Epidemiological and Experimental Studies |
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491 | (4) |
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Effect of Dietary High-Oleic Safflower Oil on Chemically Induced Colon and Mammary Carcinogenesis |
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495 | (4) |
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Chemoprevention of Colon Cancer by Dietary Fatty Acids |
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499 | (6) |
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Trans Fatty Acids and Cancer |
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505 | (4) |
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Carcinogenesis and Metastasis Are Affected by Dietary n-6/n-3 Fatty Acids |
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509 | (6) |
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| Carotenoids |
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515 | (52) |
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Growth Retardation in Human Cervical Dysplasia-Derived Cell Lines by Beta-Carotene |
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515 | (4) |
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Effects of High Dietary Fat and Beta-Carotene on Lung Carcinogenesis Induced by Diesel Exhaust Particles |
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519 | (4) |
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Significance of Beta-Carotene in Cancer |
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523 | (6) |
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Chemopreventive Potential of a-Carotene Against Mouse Liver and Lung Tumor Development: Comparison with b-Carotene and a-Tocopherol |
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529 | (4) |
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Potent Cancer Chemopreventive Activity of Alpha-Carotene Against Carcinogenesis |
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533 | (5) |
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Carotenoids As a Food Factor for Cancer Prevention: Questions to Be Solved |
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538 | (4) |
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Bioavailability, Metabolism, and Possible Mechanism of Chemoprevention by Lutein and Lycopene in Humans |
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542 | (6) |
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Bioavailability of b-Carotene in Humans |
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548 | (4) |
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Beta-Carotene Metabolism and Cancer |
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552 | (4) |
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Carotenoid Antioxidant Chemistry |
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556 | (6) |
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Lucopene: A New Carotenoid Extracted from Tomatoes |
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562 | (5) |
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| Chlorophylls |
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567 | (20) |
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Antimutagenesis in Somatic Cells of Drosophila as Monitored in the Wing Spot Test |
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567 | (5) |
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Photocleavae of DNA by Chlorophylls and Porphyrins: Electron Transfer from Nucleic Acid Base to Dyes in the Single Excited States |
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572 | (5) |
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Inhibition by Chlorella of N-Methylnitrosourea-induced Aberrant Crypt Foci in Rat Colon |
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577 | (4) |
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Inhibitory Activity of Natural Chlorophylls on the Mutagenicity of 4-Nitroquinoline 1-Oxide and 3-Amino-1-methyl-5H-Pyrido[4, 3, -b]indole in Drosophila |
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581 | (6) |
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| Flavonoids |
|
587 | (48) |
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Phytoestrogens and Prevention of Cancer |
|
|
587 | (6) |
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Antioxidant Properties of Plant Flavonoids |
|
|
593 | (5) |
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Specific Antimutagenicity of Flavonoids Against Dietary Carcinogen TRP-P-2 |
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|
598 | (5) |
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Structure-Activity Relations of Flavonoids as Antimutagens Against Cooked Food Mutagens and Nitroarenes in the Salmonella Reversion Assay |
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603 | (4) |
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Antitumor-Promoting Activities of Dihydroflav | |
