To Catch a Virus

Expert storytellers weave together the science, technological advances, medical urgencies, and human stories that chronicle the development of the field of diagnostic virology.

• Follows a historical discoveries that defined viruses and their roles in infectious diseases over a century of developments, epidemics, and molecular advances, and continuing into the 21st century with AIDS, HIV, and a future that in no way resembles the past.
• Features the great names and personalities of diagnostic virology, their contributions, their associations, and their challenges to prove findings that some considered fantasy.
• Describes how scientists applied revolutionary technologies, studying viruses, first in animal models and tissue culture and progressing to molecular and genetic techniques.
• Appeals to the pioneer and adventure-seeker who is interested in how a scientific field evolves.

List of Illustrations

Acknowledgments

Foreword

Preface

About the Authors

1. Fear or Terror on Every Countenance: Yellow Fever

2. Of Mice and Men: Animal Models of Virus Infection

3. Filling the Churchyard with Corpses: Smallpox and the Immune Response

4. What Can Be Seen: From Viral Inclusion Bodies to Electron Microscopy

5. The Turning Point: Cytopathic Effect in Tissue Culture

6. A Torrent of Viral Isolates: The Early Years of Diagnostic Virology

7. Imaging Viruses and Tagging Their Antigens

8. Immunological Memory: Ingenuity and Serendipity

9. To The Barricades: The Molecular Revolution

Appendix: Chapter Timelines

Index

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