The Chemistry and Pharmacology of Taxol and

Boehringer-Ingelheim Pharmaceuticals, Ridgefield, Connecticut. Reference for medicinal chemists on Taxol, the antitumor drug derived from the yew tree, and on related drugs in the taxane diterpenoid family. 14 contributors, 8 U.S.

List of contributors
Preface	p. 1
Naturally Occurring Taxoids	p. 7
The Structural Elucidation of Taxoids	p. 55
Paclitaxel (Taxol) Formulation and Prodrug	p. 103
Metabolism and Pharmacology of Taxoids	p. 131
Paclitaxel (Taxol) Chemistry and Structure Activity Relationships	p. 165
The Chemistry of the Taxol Side Chain: Synthesis, Modifications and Conformational Studies	p. 255
The Biochemical Pharmacology of Taxol and Mechanisms of Resistance	p. 301
Subject Index	p. 337
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The Chemistry and Pharmacology of Taxol and Its Derivatives

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