Counseling About Cancer Strategies for

Important scientific discoveries and ever-changing guidelines for how to identify and manage patients with hereditary cancer syndromes are constantly evolving. This Third Edition of Counseling About Cancer is completely updated and expanded to feature five entirely new chapters on breast cancer, colon cancer, other solid tumors, clients and families, and genetic test results and follow-up. This is the only reference and clinical book on the market for cancer genetics counselors and other healthcare providers who must quickly assimilate complex and ever-changing data on the hereditary risk for cancer.

Katherine Schneider received her Master's Degree in Public Health from Yale University School of Medicine in 1986 and was certified as a genetic counselor by the American Board of Medical Genetics in 1987. She has almost 20 years' experience as a genetic counselor and has been a cancer genetic counselor for the past 13 years. She is currently the Senior Genetic Counselor at the Dana-Farber Cancer Institute in Boston, MA, which has active high risk clinics and predictive testing programs.

Foreword	p. xi
Preface	p. xiii
Acknowledgments	p. xv
Cancer Epidemiology	p. 1
Cancer Statistics	p. 1
Cancer Etiology	p. 10
Case Examples	p. 18
Further Reading	p. 21
Cancer Detection and Treatment	p. 23
The Diagnosis of Cancer	p. 23
Tumor Classification	p. 31
Cancer Treatment	p. 37
Further Reading	p. 45
Cancer Biology	p. 47
The Malignant Cell	p. 47
Carcinogenesis	p. 52
Oncogenes	p. 59
Tumor Suppressor Genes	p. 64
Epigenetic Mechanisms	p. 70
Further Reading	p. 73
Hereditary Cancer Syndromes	p. 75
Ataxia Telangiectasia	p. 75
Autoimmune Lymphoproliferative Syndrome (Also Canale-Smith Syndrome)	p. 77
Beckwith-Wiedemann Syndrome (Also Exomphalos Macroglossia Gigantism [EMG] Syndrome)	p. 78
Birt-Hogg-Dubé Syndrome	p. 80
Bloom Syndrome	p. 82
Blue Rubber Bleb Nevus Syndrome (Also Termed Bean Syndrome)	p. 83
Breast-Ovarian Cancer Syndrome, Hereditary	p. 84
Carney Complex, Types I and II (Includes NAME Syndrome and LAMB Syndrome)	p. 87
Diamond-Blackfan Anemia	p. 89
Familial Adenomatous Polyposis (Also Attenuated FAP, Gardner's Syndrome, Turcot Syndrome, and Hereditary Desmoid Disease)	p. 90
Fanconi Anemia	p. 93
Gastric Cancer, Hereditary Diffuse	p. 95
Gastrointestinal Stromal Tumor, Familial (Also Multiple GI Autonomic Nerve Tumors)	p. 97
Juvenile Polyposis (Includes Hereditary Mixed Polyposis)	p. 98
Leiomyomatosis Renal Cell Cancer, Hereditary	p. 100
Li-Fraumeni Syndrome	p. 101
Lynch Syndrome (Also Termed HNPCC)	p. 105
Melanoma, Cutaneous Malignant (Includes Familial Atypical Mole-Malignant Melanoma Syndrome, Dysplastic Nevus Syndrome, and Melanoma-Astrocytoma Syndrome)	p. 109
Multiple Endocrine Neoplasia, Type 1 (Also Wermer Syndrome)	p. 111
Multiple Endocrine Neoplasia, Type 2 (Also Sipple Syndrome, Familial Medullary Thyroid Carcinoma Syndrome)	p. 113
MYH-Associated Polyposis	p. 115
Neuroblastoma, Familial	p. 116
Neurofibromatosis, Type 1 (Also von Recklinghausen Disease)	p. 118
Neurofibromatosis, Type 2	p. 119
Nevoid Basal Cell Carcinoma Syndrome (Also Gorlin Syndrome, Basal Cell Nevus Syndrome)	p. 121
Paraganglioma-Pheochromocytoma Syndrome, Hereditary (Including Carney-Stratakis Syndrome)	p. 123
Peutz-Jeghers Syndrome	p. 125
PTEN Hamartoma Syndrome (PHS) (Also Cowden Syndrome; Includes Bannayan-Riley-Ruvalcaba Syndrome and Proteus Syndrome)	p. 127
Renal Cell Carcinoma, Hereditary Papillary	p. 130
Retinoblastoma, Hereditary	p. 131
Rothmund-Thomson Syndrome	p. 133
Tuberous Sclerosis Complex (TSC)	p. 134
Von Hippel Lindau Syndrome	p. 137
Werner Syndrome (Also Termed Progeria of the Adult)	p. 139
Wilms Tumor, Familial (Includes Denys-Drash Syndrome, Frasier Syndrome, WAGR Syndrome)	p. 141
Xeroderma Pigmentosum (Includes XP/CS Complex, XP Variant)	p. 143
Further Reading	p. 145
All About Breast Cancer	p. 151
Overview of Breast Cancer	p. 151
Breast Cancer Management: Screening, Diagnosis, and Treatment	p. 162
Breast Cancer Syndromes	p. 171
Further Reading	p. 184
All About Colorectal Cancer	p. 187
Overview of Colorectal Cancer	p. 187
CRC Management: Screening, Diagnosis, and Treatment	p. 199
CRC Syndromes	p. 207
Further Reading	p. 218
Collecting and Interpreting Cancer Histories	p. 221
Collecting a Cancer History	p. 221
Challenges to Collecting an Accurate History	p. 242
Interpreting a Cancer History	p. 246
Case Examples	p. 255
Further Reading	p. 266
Cancer Risk Communication	p. 267
Genetic Counseling and Risk Perception	p. 267
The Communication of Risk	p. 278
Counseling Clients at various Risks	p. 289
Case Examples	p. 298
Further Reading	p. 306
Genetic Testing and Counseling	p. 309
The Logistics of Arranging Tests	p. 309
Pretest Counseling	p. 325
Results Disclosure and Follow-Up	p. 337
Case Examples	p. 346
Further Reading	p. 356
Psychosocial Aspects of Cancer Counseling	p. 357
The Psychosocial Features of Clients	p. 357
Making a Psychosocial Assessment	p. 379
Providing Additional Emotional Support	p. 394
Case Examples	p. 400
Further Reading	p. 407
Ethical Issues in Cancer Genetic Counseling	p. 409
Bioethical Principles and Guidelines	p. 409
Strategies for Resolving Ethical Dilemmas	p. 423
Types of Ethical Dilemmas in Cancer Genetic Counseling	p. 431
Issues of Justice	p. 442
Further Reading	p. 443
Specific Tumor Types and Associated Syndromes	p. 445
Review of Basic Pedigree Symbols	p. 457
Index	p. 459
Table of Contents provided by Ingram. All Rights Reserved.

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Counseling About Cancer Strategies for Genetic Counseling

Summary

Author Biography

Table of Contents

Supplemental Materials