Diabetes and Cardiovascular Disease

Harvard Medical School, Boston, MA. Offers clinicians and clinical scientists a comprehensive review of the clinical and scientific aspects of diabetic cardiovascular disease. Examines the effect of diabetes on the heart, and includes a full discussion of the macrovascular effects of the disease. DNLM: Diabetes Mellitus--complications.

Preface

vii

Contributors

xi

I Pathophysiology

The Metabolic Syndrome and Vascular Disease

3

(20)

Aresh J. Anwar

Anthony H. Barnett

Sudhesh Kumar

Effects of Insulin on the Vascular System

23

(22)

Helmut O. Steinberg

Effect of Diabetes on endothelial Function

45

(20)

Keiko Naruse

George L. King

Vascular Abnormalities in the Prediabetic State

65

(16)

A. Enrique Caballero

Su Chi Lim

Edward S. Horton

Aristidis Veves

Diabetes and Advanced Glycation End Products

81

(22)

Helen Vlassara

The Renin-Angiotensin System in Diabetic Cardiovascular Complications

103

(20)

Edward P. Feener

Diabetes and Hypertension

123

(8)

James R. Sowers

Diabetes and Dyslipidemia

131

(18)

Henry N. Ginsberg

Catherine Tuck

Diabetes and Thromobosis

149

(20)

David J. Schneider

Burton E. Sobel

Diabetes and Atherosclerosis

169

(26)

Maria F. Lopes-Virella

Animal Models of Diabetes and Atherosclerosis

195

(18)

Peter D. Reaven

Wulf Palinski

Nitric Oxide and Its Role in diabetes Mellitus

213

(24)

Michael T. Johnstone

Todd A. Caulfield

Plasminogen Activator Inhibitor-1 and Vascular Disease in diabetes Mellitus

237

(10)

Douglas E. Vaughan

II The Heart

Coronary Artery Disease in Diabetes

247

(34)

Doron Aronson

Michael T. Johnstone

Heart Failure in Diabetic Patients

281

(18)

Lawrence H. Young

Raymond R. Russell III

Deborah Chyun

Tarik Ramahi

Preoperative Assessment and Perioperative Management of the Surgical Patient with Diabetes Mellitus

299

(30)

Theodoros Laddis

Mylan C. Cohen

III Peripheral Vascular System

Epidemiology of Peripheral Vascular Disease

329

(14)

Edward J. Boyko

Nicholas L. Smith

Jessie H. Ahroni

Diabetes and Arterial Stiffness

343

(18)

Ian B. Wilkinson

Jukka Westerbacka

Hannele Yki-Jarvinen

John R. Cockcroft

Methods for Assessing Large Vessel Pathophysiology

361

(14)

Rola Saouaf

Peripheral Vascular Disease in Patients with Diabetes Mellitus

375

(10)

Allen D. Hamdan

Frank B. Pomposelli, Jr.

Gary W. Gibbons

Frank W. LoGerfo

Microcirculation

385

(14)

Diabetic Retinopathy

Lloyd Paul Aiello

Jerry Cavallerano

Diabetes and Nephropathy

399

(12)

Bijan Roshan

Richard J. Solomon

Vascular Changes and Diabetic Neuropathy

411

(20)

Rayaz A. Malik

Solomon Tesfaye

John D. Ward

Microcirculation of the Diabetic Foot

431

(16)

Osama Hamdy

K. Abuelenin

Aristidis Veves

Index

447

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Diabetes and Cardiovascular Disease

Summary

Table of Contents

Supplemental Materials