Equine Clinical Pathology

Equine Clinical Pathology is the first complete resource for hematology and clinical chemistry in horses. Encompassing the basic principles and advanced interpretation, the book’s single-species approach to pathology allows for focused coverage of the unique disease characteristics of equids. Equine Clinical Pathology is equally useful for anyone using clinical pathology as a diagnostic tool, from beginning student to experienced specialist.

The heart of the book is organized by body system, making it easy to find and apply information. Chapters cover general laboratory medicine, including instruments and techniques, hematology, and proteins as well as specific organs, such as the kidney and liver. Equine Clinical Pathology is a useful bench-side reference for anyone involved in laboratory medicine for the horse.

Raquel M. Walton, VMD, MS, PhD, is a senior Clinical Pathologist at the Animal Medical Center in New York, New York.

a. The technology of hematology (including point-of-care instruments).

b. Clinical chemistry instrumentation principles (including point-of-care instruments).

c. Data interpretation from a clinical pathologic perspective.

d. Reference intervals and test validation.

2. Equine hematology.

a. CBC interpretation.

b. Blood film evaluation.

c. Erythrocytes and RBC indices.

d. Reticulocytes.

e. White blood cells and the leukogram.

f. Bone marrow evaluation.

3. Immunohematology and hemostasis.

a. Blood typing.

b. Cross-matching.

c. Immune-mediated hemolytic anemia.

i. Neonatal isoerythrolysis.

ii. Clostridial infections.

iii. Drug-associated.

d. Coagulation assays.

4. The liver.

a. Hepatic enzymes.

b. Liver function tests.

c. Ancillary testing.

d. Cytopathology.

5. The kidney.

a. Renal function tests.

b. Markers of glomerular and tubular damage.

c. Urinalysis (including fractional excretion tests).

6. Acid-base and electrolyte evaluation.

a. Blood gas.

b. Sodium and chloride.

c. Potassium.

d. Calcium and phosphorus.

7. Proteins.

a. Inflammation.

i. Fibrinogen.

ii. Acute phase proteins.

iii. Clinical pathology of colic.

iv. Clinical pathology of laminitis.

b. Passive transfer of immunoglobulins.

8. Laboratory assessment of lipid and glucose metabolism.

a. Equine syndrome X, metabolic syndrome, and grain-associated disorder.

b. Hyperlipidemia of miniature horses.

9. Laboratory markers of muscle injury.

a. Enzymes.

b. Myoglobin.

10. Endocrine evaluation.

a. Equine pituitary pars intermedia dysfunction.

b. Thyroid hormone.

c. Reproductive hormones.

i. Fertility in the mare.

ii. The stallion (includes hormones; assessment of sperm; use of ALP in seminal plasma).

11. Evaluation of fluids.

a. Pathogenetic mechanisms of effusions.

b. Peritoneal.

c. Pleural.

d. Synovial.

e. CSF.

12. Cytology of the airway.

a. Tracheal wash and bronchoalveolar lavage.

i. Inflammatory airway disease.

ii. Heaves.

iii. Infection.

iv. Exercise induced pulmonary hemorrhage

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