Evidence-Based Medical Monitoring : From

Monitoring is a major component of management of chronic diseases such as diabetes, cardiovascular disease, arthritis and depression. Yet poor monitoring means healthcare costs are rising.This book discusses how monitoring principles adopted in other spheres such as clinical pharmacology and evidence-based medicine can be applied to chronic disease in the global setting. With contributions from leading experts in evidence-based medicine, it is a ground-breaking text for all involved in delivery of better and more effective management of chronic illnesses.

Professor Paul Glasziou, University of Oxford, Department of Primary Health Care and Director of the Centre for Evidence-based Medicine, Oxford. Paul is a leading figure in evidence-based medicine. He teaches courses and organises workshops both at the Centre in Oxford and the other centres around the world (eg McMaster, Bond University- Australia).

Les Irwig, Professor in the School of Public Health, University of Sydney He teaches courses on diagnostic test assessment, meta-analysis and guideline development, and advanced epidemiological methods. He is especially interested in the application of epidemiological methods to provide the evidence on which to base public health and clinical decisions.

Dr Jeffery Aronson, Clinical Reader in Pharmacology, University of Oxford, UK.

Contributors	p. ix
The Theory of Monitoring
Introductory Material
An introduction to monitoring therapeutic interventions in clinical practice	p. 3
A framework for developing and evaluating a monitoring strategy	p. 15
The Measurement
Developing monitoring tools: integrating the pathophysiology of disease and the mechanisms of action of therapeutic interventions	p. 31
Biomarkers and surrogate endpoints in monitoring therapeutic interventions	p. 48
Choosing the best monitoring tests	p. 63
The Control Phases
Monitoring the initial response to treatment	p. 75
Control charts and control limits in long-term monitoring	p. 90
Developing a monitoring schedule: frequency of measurement	p. 103
How should we adjust treatment?	p. 114
The Psychology of Monitoring
Monitoring as a learning and motivational tool	p. 123
Monitoring from the patient's perspective: the social and psychological implications	p. 140
The Evaluation of Monitoring Techniques
Evaluating the effectiveness and costs of monitoring	p. 158
Good practice in delivering laboratory monitoring	p. 166
Point-of-care testing in monitoring	p. 179
Monitoring for the adverse effects of drugs	p. 194
The Practice of Monitoring
Monitoring diabetes mellitus across the lifetime of illness	p. 213
Oral anticoagulation therapy (OAT)	p. 229
Monitoring cholesterol-modifying interventions	p. 245
Monitoring levothyroxine replacement in primary hypothyroidism	p. 254
Monitoring in renal transplantation	p. 286
Monitoring in pre-eclampsia	p. 303
Monitoring in intensive care	p. 313
Monitoring intraocular pressure in glaucoma	p. 325
Monitoring in osteoarthritis	p. 335
Index	p. 357
Table of Contents provided by Ingram. All Rights Reserved.

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Evidence-Based Medical Monitoring : From Principles to Practice

Summary

Author Biography

Table of Contents

Supplemental Materials