Forensic Pharmacology Medicines, Mayhem, and Malpractice
, by Ferner, R. E.; Norman, Elizabeth; Rawlins, M. D.Note: Supplemental materials are not guaranteed with Rental or Used book purchases.
- ISBN: 9780198548263 | 0198548265
- Cover: Hardcover
- Copyright: 2/22/1996
Forensic Pharmacology offers a unique and comprehensible account of pharmacological methods and knowledge, and how to use them to solve problems in crimes from drunken driving to murder. It also deals with negligence in giving drugs, and adverse reactions to drugs. The text is enlivened bycases from the literature and from the authors' experience. Appendices give detailed examples of pharmacological problems and their solutions; tables and equations for alcohol calculations; and data for medicines encountered in forensic work. Experts do not always understand what lawyers want of them, and lawyers fail to appreciate that experts in medicine and pharmacology may not be experts in the law. The section entitled 'legal considerations' was written by a barrister with wide experience of using expert evidence and explainsclearly the legal principles. It also contains some helpful hints on how to deal with court procedure and adversarial lawyers.
Introduction | 1 | (2) | |||
Part 1 General considerations | 3 | (68) | |||
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Part 2 Specific problems | 71 | (40) | |||
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Part 3 Specific drugs of forensic importance | 111 | (74) | |||
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Appendix A Pharmacokinetic calculations | 185 | (5) | |||
A.1 Some further details of the dosage of drugs | 185 | (1) | |||
A.2 Concentration in calculations | 186 | (1) | |||
A.2.1 Calculating amount from concentration | 186 | (1) | |||
A.2.2 Calculating volume from concentration | 186 | (1) | |||
A.3 Calculations using volume of distribution | 186 | (2) | |||
A.3.1 Using volume of distribution and concentration to estimate dose | 186 | (1) | |||
A.3.2 A forensic example | 187 | (1) | |||
A.4 The calculations of drug disposition | 188 | (1) | |||
A.4.1 First-order kinetics | 188 | (2) | |||
Appendix B Detailed aspects of measurement of ethanol and calculations based on ethanol concentration | 190 | (10) | |||
B.1 Peak-height ratios in gas chromatography | 190 | (1) | |||
B.2 Watson's equations for total body water (TBW) in human subjects | 190 | (1) | |||
B.3 The use of Watson's formula and the Widmark equation | 191 | (1) | |||
B.4 Back-calculation of ethanol concentration | 191 | (2) | |||
B.5 Calculations in the hip-flask defence | 193 | (3) | |||
B.6 Calculations in the lacing defence | 196 | (1) | |||
B.7 The ethanol content of alcoholic drinks | 197 | (3) | |||
Appendix C Brief details of some drugs of forensic importance | 200 | (17) | |||
C.1 Introduction | 200 | (1) | |||
C.2 Amitriptyline | 200 | (1) | |||
C.3 Amylobarbitone (Amobarbital in the United States) | 201 | (1) | |||
C.4 Buspirone | 201 | (1) | |||
C.5 Chlordiazepoxide | 202 | (1) | |||
C.6 Chlormethiazole | 202 | (1) | |||
C.7 Chlorpromazine | 203 | (1) | |||
C.8 Clozapine | 204 | (1) | |||
C.9 Dexamphetamine, D-amphetamine | 205 | (1) | |||
C.10 Diamorphine, heroin | 205 | (1) | |||
C.11 Diazepam | 206 | (1) | |||
C.12 Fluoxetine | 207 | (1) | |||
C.13 Fluphenazine | 208 | (1) | |||
C.14 Haloperidol | 209 | (1) | |||
C.15 Insulin | 210 | (1) | |||
C.16 Lorazepam | 210 | (1) | |||
C.17 Morphine | 210 | (1) | |||
C.18 Pethidine (meperidine in the United States) | 211 | (1) | |||
C.19 Temazepam | 212 | (1) | |||
C.20 Thiopentone (thiopental in the United States) | 212 | (1) | |||
C.21 Thioridazine | 213 | (1) | |||
C.22 Triazolam | 214 | (1) | |||
C.23 Vincristine | 214 | (1) | |||
C.24 Warfarin (warfarin sodium) | 215 | (1) | |||
References | 217 | (20) | |||
Index | 237 |
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