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From Enzyme Models to Model Enzymes

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From Enzyme Models to Model Enzymes by Kirby, Anthony J.; Hollfelder, Florian, 9780854041756
Note: Supplemental materials are not guaranteed with Rental or Used book purchases.
  • ISBN: 9780854041756 | 0854041753
  • Cover: Hardcover
  • Copyright: 10/1/2009
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Designing artificial systems with catalytic efficiencies to rival those of natural enzymes is one of the great challenges facing science today. This introduction to the exciting area of artificial enzymes is suitable for both students and more senior researchers. It starts with a systematic review of the key properties of natural enzymes. This is followed by a summary of the mechanisms involved in the major classes of reactions and a logical progression to the first, rudimentary artificial enzymes catalyzing them. An analysis of the classical design-based approach to catalysis by enzyme mimics leads on to a summary of recent advances in creating and improving catalysts. Key data interpretation skills are introduced in a guided approach that links kinetic measurements with their chemical and biological interpretation.

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