Gene Therapy of Cancer : Translational Approaches from Preclinical Studies to Clinical Implementation

This book presents cancer gene therapy and its proposed use in the search for the prevention of cancer. Contributions from leaders in the field present laboratory research, various types of vector genes and gene therapy strategies, as well as clinical trials currently under way. The volume covers gene therapy as it evolves from laboratory technology and is parlayed into clinical investigations. Gene Therapy of Cancer describes the strategies for intervention and provides data demonstrating efficacy in in vitro as well as in vivo preclinical and clinical studies which lead to specific strategies for gene therapy. This volume is a comprehensive look into the subject of genetic approaches to cancer and is an important reference for scientists, students, and a general clinical audience. Key Features * Provides a comprehensive review of gene therapy targets in cancer * Discusses specific strategies for gene therapy intervention and current gene therapy vehicles * Provides data demonstrating clinical studies * Explains the requirements of bringing new technologies to clinical use