History of the Synapse

The History of the Synapse provides a history of those discoveries concerning the identification and function of synapses that provide the foundations for research during this new century with a personal view of the process by which new concepts have developed. Previously published as essays, the chapters in this book provide a history of various aspects of synaptic function, beginning with the evolution over two and a half thousand years and how progress was made in the establishment of a conceptual structure that would allow the synapse to be identified at the beginning of the 20th century. Numerous illustrations explain either the technical approach or the experimental finding.

Max Bennett is professor of physiology at the University of Sydney.

The Early History of the Synapse: from Plato to Sherrington
Emergence of the Concept of Transmitter Release at Peripheral and Central Synapses
The Discovery of Acetylcholine and the Concept of Receptors at Synapses
The Discovery of Adrenaline and the Concept of Autoreceptors at Synapses
The Discovery of Amino-acid Transmission at Synapses in the Central Nervous System
Monoaminergic Synapse and Schizophrenia: The Discovery of Neuroleptics
The Discovery of Transmitters other than
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History of the Synapse

Summary

Author Biography

Table of Contents

Supplemental Materials