Immunoendocrinology in Health and Disease

One of the first comprehensive references dealing specifically with this new field of interdisciplinary research in medicine, Immunoendocrinology in Health and Disease offers a full scientific picture of where the immune and neuroendocrine systems intersect-placing current understanding of system components, mechanisms, and functions side by side with clinical results illustrating the many ramifications of their interaction in human health and disease management.

Preface

iii

Contributors

xi

Fundamental Aspects

A Global View of Immunological Development and Biology

1

(20)

Rachel Allen

Anne Cooke

Common Signaling in the Neuroendocrine and Immune Systems

21

(30)

Nithya Krishnan

Arthur R. Buckley

Hypothalamic-Pituitary-Adrenal Axis Effects on Innate and Adaptive Immunity

51

(14)

Emmanouil Zoumakis

Ilia Elenkov

George Chrousos

Glucocorticoids and the Immune System

65

(18)

G. Jan Wiegers

Ilona E.M. Stec

Pia U. Muller

Georg Wick

Cytokines and Leptin as Mediators of the Hypothalamo-Pituitary-Adrenal Axis

83

(24)

Rolf-Christian Gaillard

Role of Pro-Inflammatory Cytokines in Regulating the Hypothalamic-Pituitary-Gonadal Axis of the Male Rat

107

(20)

Catherine Rivier

Sex Hormones and B Cells

127

(18)

Christine M. Grimaldi

Elena Peeva

Betty Diamond

Vitamin D3 in Control of Immune Response

145

(18)

Chantal Mathieu

Evelyne van Etten

Lut Overbergh

Roger Bouillon

The Growth Hormone/Insulin-like Growth Factor-I Axis and the Immune System

163

(30)

Ron Kooijman

Somatostatin Control of Immune Functions

193

(14)

P. M. van Hagen

V. Dalm

L. J. Hofland

D. Ferone

S. W. J. Lamberts

Prolactin and the Immune System

207

(34)

Robert Hooghe

Nele Martens

Elisabeth L. Hooghe-Peters

VIP and PACAP Immune Mediators Involved in Homeostasis and Disease

241

(22)

Rosa P. Gomariz

Carmen Martinez

Catalina Abad

Mario Delgado

Maria Guillerma Juarranz

Javier Leceta

Neurotransmitters Talk to T Cells in a Direct, Powerful, and Contextual Manner Affecting Key Immune Functions

263

(26)

Mia Levite

Role of Neuropeptides in T-Cell Differentiation

289

(16)

Doina Ganea

Mario Delgado

Natriuretic Peptides and Inflammation

305

(14)

Angelika M. Vollmar

Alexandra K. Kiemer

Neuroendocrinology of the Thymus

319

(18)

Wilson Savino

Mireille Dardenne

The Central Role of the Thymus in the Development of Self-Tolerance and Autoimmunity in the Neuroendocrine System

337

(20)

Vincent Geenen

Fabienne Brilot

Isabelle Hansenne

Celine Louis

Chantal Charlet-Renard

Henri Martens

Two-Way Communication Between Mast Cells and the Nervous System

357

(24)

Hanneke P. M. van der Kleij

Michael Blennerhassett

John Bienenstock

Peripheral Nervous System Programming of Dendritic Cell Function

381

(12)

Georges J. M. Maestroni

Neuroendocrine Host Factors in Susceptibility and Resistance to Autoimmune/Inflammatory Disease

393

(24)

Jeanette I. Webster

Esther M. Sternberg

Clinical Aspects

Autoimmune Type 1 Diabetes

417

(22)

Edwin A. M. Gale

Polly J. Bingley

Autoimmune Central Diabetes Insipidus

439

(22)

Annamaria De Bellis

Antonio Bizzarro

Antonio Bellastella

Autoimmune Thyroid Disease

461

(30)

Marian Elizabeth Ludgate

Gherardo Mazziotti

Addison's Disease and Autoimmune Polyglandular Syndromes

491

(46)

Corrado Betterle

Premature Ovarian Failure

537

(34)

Annemieke Hoek

Hemmo A. Drexhage

Myasthenia Gravis

571

(22)

Alexander Marx

Philipp Strobel

Hans Konrad Muller-Hermelink

Rheumatoid Arthritis

593

(14)

Maurizio Cutolo

Rainer Straub

Aging and Neuroimmunoendocrinology

607

(12)

Rainer Straub

Maurizio Cutolo

Quality of Life in Asthma and Rhinitis

619

(12)

Jean Bousquet

Philippe J. Bousquet

Pascal Demoly

Atopic Dermatitis

631

(16)

Markus Bohm

Thomas Luger

Neuroendocrine Control of Th1 and Th2 Responses: Clinical Implications

647

(26)

Ilia Elenkov

HIV Infection and the Central Nervous System

673

(20)

Marcus Kaul

Stuart A. Lipton

Opioid Receptors and HIV Infection

693

(14)

Burt M. Sharp

Mechanisms of Cytokine-Induced Sickness Behavior

707

(14)

Robert Dantzer

Jan-Pieter Konsman

Patricia Parnet

Immunotherapy of Neuroendocrine Tumors

721

(16)

Matthias Schott

Jochen Seissler

Werner A. Scherbaum

Glucocorticoid Resistance in Inflammatory Diseases

737

(10)

Denis Franchimont

George Chrousos

Index

747

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Immunoendocrinology in Health and Disease

Summary

Table of Contents

Supplemental Materials