Medical Cytogenetics

The only monograph on cytogenetics for the pathologist, this up-to-the-minute reference/text contains the most up-to-date research findings on many important topics in medical genetics-notably FISH (fluorescent in situ hybridation)-based molecular cytogenetic technologies and spectral karyotyping. An excellent resource for cytogeneticists preparing for the certifying examination in Clinical Cytogenetics offered by the American Board of Medical Genetics (ABMG). Written by nearly 30 distinguished international contributors, Medical Cytogenetics covers the history of the field, tissue culturing and staining techniques, and clinical applications of FISH, as well as other methods for genetic studies and chromosomal analysis supplies numerous examples and case reports examines reproductive dysfunctions such as in-utero abnormalities, male infertility, and failure to conceive investigates chromosomal abnormalities associated with myeloid hematopoietic disorders, lymphoid neoplasms, and solid tumors such as those associated with breast cancer reviews means of obtaining accreditation or licenses, use of external peer reviews and voluntary inspections, proficiency testing, and regulatory oversight and more! Thoroughly referenced with over 1800 bibliographic citations, and supplemented with a useful glossary, a large number of practice questions, and over 40 color photographs, Medical Cytogenetics is a pragmatic, hands-on reference for pathologists, geneticists, cytogenetic technologists, molecular and cell biologists, clinical and medical oncologists, hematologists, neurologists, pediatricians, endocrinologists, obstetricians, gynecologists, and primary care physicians, and an exceptional text for upper-level undergraduate, graduate, and medical students in these disciplines.

John Anastasi, M.D. Department of Pathology, The University of Chicago Medical Center, Chicago, Illinois Jan K. Blancato, Ph.D., F.A.C.M.G. Institute for Molecular and Human Genetics, Georgetown University Medical Center, Washington, D.C. Zhong Chen, M.D. Department of Cytogenetics and Pediatrics, University of Utah School of Medicine, Salt Lake City Gabriela Adelt Green, M.D. Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland Bassem R. Haddad, M.D. Department of Obstetrics and Gynecology and Institute for Molecular and Human Genetics, Georgetown University Medical Center, Washington, D.C. Kerstin Heselmeyer-Haddad, Ph.D. Division of Clinical Sciences, Department of Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland Gerald A. Hoeltge, M.D. Department of Clinical Pathology, The Cleveland Clinic Foundation, Ohio Jila Khorsand, M.D. Department of Pathology, Boston University, Boston, Massachusetts, and Department of Hematology Laboratory, Roger Williams Medical Center, Providence, Rhode Island Bruce R. Korf, M.D., Ph.D. Partners Center for Human Genetics, Harvard Medical School and Partners HealthCare, Boston, Massachusetts Alan N. Lamb, Ph.D., F.A.C.M.G. Department of Cytogenetics, Genzyme Genetics, Santa Fe, New Mexico Roger V. Lebo, Ph.D., F.A.C.M.G. Department of Pediatrics, Center for Human Genetics, Boston University School of Medicine, Massachusetts Hon Fong L. Mark, Ph.D., F.A.C.M.G. Brown University School of Medicine and Rhode Island Department of Health, Providence, and KRAM Corporation, Barrington, Rhode Island Yvonne Mark, M.D. Department of Family Medicine, Memorial Hospital of Rhode Island, Pawtucket, and Brown University School of Medicine, Providence Wayne A. Miller, M.D. Perinatal Diagnosis Center, Inc., Lexington, Massachusetts Hesed M. Padilla-Nash, Ph.D. Department of Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland Reed E. Pyeritz, M.D., Ph.D. Center for Medical Genetics, Allegheny General Hospital, Pittsburgh, Pennsylvania Susana C. Raimondi, Ph.D. Department of Pathology and Laboratory Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee Thomas Ried, M.D. Department of Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland Diane Roulston, Ph.D. Division of Hematology/Oncology, Department of Medicine, The University of Chicago Medical Center, Illinois Avery A. Sandberg, M.D., D.Sc. Department of DNA Diagnostics, St. Joseph's Hospital and Medical Center, Phoenix, Arizona Nancy R. Schneider, M.D., Ph.D. Department of Pathology, University of Texas Southwestern Medical Center, Dallas Evelin Schrock, M.D. Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland Mark Sigman, M.D. Division of Urology, Department of Surgery, Brown University School of Medicine, Providence, Rhode Island Avirachan T. Tharapel Ph.D. Department of Pediatrics and Pathology, The University of Tennessee, Memphis Sugandhi A. Tharapel, Ph.D., F.A.C.M.G. Veterans Affairs Medical Center and Department of Pediatrics and Pathology, The University of Tennessee, Memphis Vijay S. Tonk, Ph.D. Department of Pediatrics, Texas Tech University Health Science Center, Lubbock Tim Veldman, B.S. Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland Dorothy Warburton, Ph.D. Departments of Genetics and Development and Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York Sandra R. Wolman, M.D. Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland Herman E. Wyandt, Ph.D., F.A.C.M.G. Departments of Cytogenetics and Pathology, Center for Human Genetics, Boston University School of Medicine, Massachusetts Carolyn Te Young, M.D. Department of Pathology and Laboratory Medicine, Rhode Island Blood Center and Brown University, Providence