Molecular Biology of Cancer Mechanisms, Targets, and Therapeutics

Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students.

Using the hallmarks of cancer as a starting point, the book looks at the cellular and molecular mechanisms underpinning the transformation of cells into cancer cells. After discussing the theory, each chapter then demonstrates how this knowledge can be directly applied to the development of new targeted therapies, giving the reader a clear appreciation of how our understanding of the theory can be translated into new approaches for tackling the disease.

The new edition draws on the latest research in cancer biology, highlighting fundamental concepts and re-emphasising pre-existing concepts. The book features a variety of learning features--'Pause and think', 'How do we know that?', self-tests and activities--to help students engage with, and master, the concepts presented. The emphasis is on acquiring a solid understanding of the essentials and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit.

Molecular Biology of Cancer is available for students and institutions to purchase in a variety of formats, and is supported by online resources.

The online resources include:

For students:
- Multiple choice questions
- Web links to additional cancer biology resources

For registered adopters of the book:
· Figures from the book, available to download

Lauren Pecorino, Principal Lecturer in Cancer Biology, University of Greenwich

Dr Lauren Pecorino obtained her PhD in Cell and Developmental Biology at the State University of New York at Stony Brook, USA. She then moved to London to carry out a post-doctoral tenure at the Ludwig Institute for Cancer Research where she studied the phenomenon of limb regeneration. Here she used
a technique called biolistics, using a 'gene gun' to shoot gold bullets coated with DNA to introduce genes into the regenerating limbs of live newts. Since 1996, Lauren has been a member of academic staff at the University of Greenwich, where she developed her interest in teaching Cancer Biology. In
2018, Lauren was made a Principal Fellow of the Higher Education Academy.