Molecular Techniques for the Study of

Providing a broad overview of the microbial pathogens associated with hospital-acquired human illness, Techniques for the Study of Hospital Acquired Infection examines the cost-effective use of laboratory techniques in nosocomial infectious disease epidemiology and control. This concise guide addresses the cost benefits of combining modern molecular techniques with the traditional activities of infection control departments. The book is useful as a guide to hospital infection control programs as well as a text for medical practitioners, grad/medical students, researcher scientists, population biologists, molecular biologists, and microbiologists.

Shabbir Simjee, Ph.D. is a Senior Microbiologist at Eli Lilly & Company, where he specializes in antimicrobial susceptibility testing and the interpretation of antimicrobial susceptibility data according to NCCLS and BSAC standards. He has served as Editor of The Journal of Antimicrobial Chemotherapy and currently serves as an Editorial Board Member for Antimicrobial Agents and Chemotherapy as well as Section Editor (Molecular Microbiology) for the International Journal of Antimicrobial Agents. Dr. Simjee has served on a number of FDA advisory committees.

Steven Foley, Ph.D. is an Associate Research Scientist for the National Farm Medicine Center, Marshfield Clinic Research Foundation, as well as Clinical Professor of Clinical Microbiology at the University of Wisconsin. His research interests include understanding the mechanisms that Escherichia coli employ to resist being killed by vertebrate immune system constituents and the development and utilization of genotypic and phenotypic methods to track enteric bacterial pathogens and their virulence and antimicrobial resistance factors through the food animal production environment.

Anne Chen, M.D. is a Senior Staff Physician, Division of Infectious Diseases at the Henry Ford Hospital, Detroit, Michigan as well as Assistant Professor of Medicine at Wayne State University School of Medicine. She is Board Certified in Internal Medicine and Infectious Disease and is currently researching Candida epidemiology in the burn unit.

Marcus J. Zervos, M.D. is the Medical Director of Infection Control and Division Head of Infectious Disease, Department of Internal Medicine at Henry Ford Hospital as well as Clinical Professor of Medicine in the Department of Internal Medicine, Infectious Diseases Section at Wayne State University School of Medicine. He chairs the Infection Control Committee at the Henry Ford Hospital and is certified by the American Board of Internal Medicine and Infectious Diseases. Dr. Zervos serves on the boards of several journals in infectious disease, microbiology and internal medicine, including Infectious Diseases in Clinical Practice and his role as Section Editor for the journal Infection Control and Hospital Epidemiology.

Contributors	p. ix
Foreword	p. xi
Preface	p. xiii
Introduction To Healthcare-Associated Infections And Their Control	p. 1
The Hospital And Ambulatory Care Environment	p. 3
Pathogen Transmission In The Healthcare Setting	p. 23
Infection Control Basics	p. 39
Cost Effectiveness Of Infection Control Program	p. 55
Outbreak Investigations (Importance Of the Healthcare Epidemiologist)
Pathogen Elimination: Antibiotic And Disinfectant Use And The Development Of Resistance	p. 83
Techniques To Characterize Nosocomial Pathogens	p. 105
Rapid Pcr Screening Methods	p. 107
Restriction Analysis Techniques	p. 135
Pulsed-Field Gel Electrophoresis	p. 145
Application Of Techniques To Characterize Predominant Nosocomial Pathogens	p. 161
Staphylococcus Aureus	p. 163
Escherichia ColI	p. 179
Fungal Infections	p. 193
Index	p. 217
Table of Contents provided by Ingram. All Rights Reserved.

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Molecular Techniques for the Study of Hospital Acquired Infection

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