Neurobiological Mechanisms of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetamines
, by Ali, Syed F.
- ISBN: 9781573312806 | 1573312800
- Cover: Paperback
- Copyright: 10/1/2000
| Preface | p. xi |
| General Introduction | |
| Studies of Amphetamine or Methamphetamine Psychosis in Japan: Relation of Methamphetamine Psychosis to Schizophrenia | p. 1 |
| Gene Expression and Molecular Mechanisms of Drug Addiction | |
| Probing the Role of the Dopamine D1 Receptor in Psychostimulant Addiction | p. 13 |
| Activation of an Effector Immediate-early Gene arc by Methamphetamine | p. 22 |
| Two Inbred Strains of Rats, Fischer 344 and Lewis, Showed Differential Behavior and Brain Expression of Corticosterone Receptor mRNA Induced by Methamphetamine | p. 33 |
| C-fos and egr-1 Immediate-early Gene Induction by Cocaine and Cocaethylene in Rat Brain: A Comparative Study | p. 46 |
| Expression and Distribution of GABA[subscript A] Receptor Subtypes in Human Alcoholic Cerebral Cortex | p. 58 |
| Microtubule-associated Protein 2 (MAP2) and c-fos Expression in the Rat Prefrontal Cortex following Subchronic Treatment with Substituted Amphetamines | p. 65 |
| Drugs of Abuse and Medication Development: Cocaine | |
| Methamphetamine Dependence: Medication Development Efforts Based on the Dual Deficit Model of Stimulant Addiction | p. 71 |
| Oxidative Stress and Drugs of Abuse: Neurodegeneration and Neuroprotection | |
| Serum Withdrawal Potentiates the Toxic Effects of Methamphetamine in Vitro | p. 82 |
| Molecular Footprints of Neurotoxic Amphetamine Action | p. 92 |
| Comparison between the Role of the Neuronal and Inducible Nitric Oxide Synthase in Methamphetamine-induced Neurotoxicity and Sensitization | p. 104 |
| Neuroprotective Role of Estrogen upon Methamphetamine and Related Neurotoxins within the Nigrostriatal Dopaminergic System | p. 112 |
| Restorative Effects of GDNF on Striatal Dopamine Release in Rats Treated with Neurotoxic Doses of Methamphetamine | p. 127 |
| Effect of d-Amphetamine and Sydnocarb on the Extracellular Level of Dopamine, 3,4-Dihydroxyphenylacetic Acid, and Hydroxyl Radicals Generation in Rat Striatum | p. 137 |
| Methamphetamine-induced Oxidative Stress in Cultured Mouse Astrocytes | p. 146 |
| Prevention of Dopaminergic Neurotoxicity by Targeting Nitric Oxide and Peroxynitrite: Implications for the Prevention of Methamphetamine-induced Neurotoxic Damage | p. 157 |
| Specific Neuronal Markers in Substituted Amphetamines-induced Neurotoxicity | |
| Serotonin Transporters, Serotonin Release, and the Mechanism of Fenfluramine Neurotoxicity | p. 172 |
| Dopamine Uptake Blockers Nullify Methamphetamine-induced Decrease in Dopamine Uptake and Plasma Membrane Potential in Rat Striatal Synaptosomes | p. 187 |
| Age as a Susceptibility Factor in the Striatal Dopaminergic Neurotoxicity Observed in the Mouse following Substituted Amphetamine Exposure | p. 194 |
| Correlation between 5-HT Content and Uptake Site Density following (S)-MDMA and Dexfenfluramine-induced Depletion, and with Neuroprotection by the Glycine Site-specific NMDA Antagonist ACEA 1021 | p. 208 |
| Immunomodulating Activity of MDMA | p. 215 |
| Pharmacology of MDMA in Humans | p. 225 |
| Methamphetamine and Other Drugs of Abuse: Neurobiomarkers | |
| Protein Phosphorylation Cascades Associated with Methamphetamine-induced Glial Activation | p. 238 |
| Effect of Acute and Chronic Administration of Methamphetamine on Calcium-Calmodulin Dependent Protein Kinase II Activity in the Rat Brain | p. 263 |
| Calpain Upregulation in Spinal Cords of Mice with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's Disease | p. 275 |
| The Effects of DCG-IV and L-CCG-1 upon Phencyclidine (PCP)-induced Locomotion and Behavioral Changes in Mice | p. 284 |
| Susceptibility to Subsequent Episodes in Spontaneous Recurrence of Methamphetamine Psychosis | p. 292 |
| Plasma Catecholamines during an Ultrarapid Heroin Detoxification | |
| Directed Coherence of EEG on ICSS Rats with Methamphetamine-induced Hyperactivity and Stereotyped Behavior | p. 311 |
| Ca[superscript 2+] Oscillations in Response to Methamphetamine in Dopamine Neurons of the Ventral Tegmental Area in Rats Subchronically Treated with This Drug | p. 316 |
| Behavioral Responses to Repeated Cocaine Exposure in Mice Selectively Bred for Differential Sensitivity to Pentobarbital | p. 323 |
| The Neurochemical Basis for the Behavioral Effects of Triadimefon | p. 336 |
| Drugs of Abuse and Medication Development: Ibogaine | |
| Noribogaine (12-Hydroxyibogamine): A Biologically Active Metabolite of the Antiaddictive Drug Ibogaine | p. 354 |
| 18-Methoxycoronaridine (18-MC) and Ibogaine: Comparison of Anti-addictive Efficacy, Toxicity, and Mechanisms of Action | p. 369 |
| Application of Electrophysiological Method to Study Interactions between Ibogaine and Cocaine | p. 387 |
| Ibogaine: Complex Pharmacokinetics, Concerns for Safety, and Preliminary Efficacy Measures | p. 394 |
| Prenatal Exposure and Postnatal Outcome | |
| The Relationship between Neural Alterations and Behavioral Deficits after Prenatal Exposure to Heroin | p. 402 |
| Effects of Chronic in Utero Exposure to Cocaine on Behavioral Adaptability in Rhesus Monkey Offspring When Examined in Adulthood | p. 412 |
| Effects of Neonatal Exposure to Cocaine in the Development of the Neurotransmitters Retinal Systems: An Immunocytochemical and Neurochemical Study | p. 418 |
| Neonatal Methamphetamine in the Rat: Evidence for Gender-specific Differences upon Tyrosine Hydroxylase Enzyme in the Dopaminergic Nigrostriatal System | p. 431 |
| Index of Contributors | p. 439 |
| Table of Contents provided by Syndetics. All Rights Reserved. |
What is included with this book?
The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.
The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.
Please wait while the item is added to your bag...
