Oxford Textbook of Neurohaematology

The Oxford Textbook of Neurohaematology is a single source of knowledge on the diverse neurological conditions associated with malignant and classical haematological diseases. The book covers the full range of haematological diseases, both malignant and classical, that impact the central, peripheral, and autonomic nervous systems.

The book is divided into three sections. In the first section, neurological conditions associated with malignant haematological diseases are presented. This section begins with chapters on primary haematological malignancies of the nervous system including primary central nervous system lymphomas, vitreoretinal lymphoma, and other rare primary malignancies such as Hodgkin disease and lymphoproliferative disorders. Next, a chapter on histiocytic tumours of the central nervous system presents the neurological conditions associated with the Langerhans and non-Langerhans histiocytoses. This is followed by chapters covering the neurological complications of systemic myeloid and lymphoid malignancies. The second section of the book covers neurological complications of the treatments used in the management of haematological malignancies such as chemotherapy, radiation, and immunotherapy including chimeric antigen receptor T cells. The third and final section of the book features chapters on the neurological complications associated with classical haematological diseases including disorders of red blood cells (e.g., sickle cell anaemia), disorders of platelets and coagulation (e.g., immune thrombocytopenia), and disorders of white blood cells (e.g., hyperviscosity syndrome).

Edited by leading authorities in the field, this book will serve as a useful resource for neurologists, haematologists, and oncologists, as well as for subspecialists and allied health professionals involved in the management of haematological diseases and their neurological manifestations.

Tracy Batchelor, Brigham and Women's Hospital, and Harvard Medical School, Boston, USA,Joshua P. Klein, Brigham and Women's Hospital, and Harvard Medical School, Boston, USA,Andrés José María Ferreri, IRCCS San Raffaele Scientific Institute, Milan, Italy,Lisa M. DeAngelis, Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical College, New York, USA

Tracy Batchelor is the Chair, Department of Neurology at Brigham and Women's Hospital, Co-Leader of the Neuro-Oncology Program at the Dana-Farber/Harvard Cancer Center, and the Miriam Sydney Joseph Professor of Neurology at Harvard Medical School, Boston, USA. He has spent his career focused on malignant haematological diseases that involve the central nervous system and co-founded the International Primary CNS Lymphoma Collaborative Group.

Joshua P. Klein is Vice Chair for Clinical Affairs and the founding Chief of the Division of Hospital Neurology in the Department of Neurology at Brigham and Women's Hospital, and Associate Professor of Neurology and Radiology at Harvard Medical School, Boston, USA. He specializes in hospital neurology and diagnostic neuroimaging. He has served on the Board of Directors of the Neurohospitalist Society and the American Society of Neuroimaging for many years and is Editor-in-Chief of the journal The Neurohospitalist. He is a Fellow of the American Neurological Association, the American Society of Neuroimaging, and the American Academy of Neurology.

Lisa M. DeAngelis is Physician-in-Chief and Chief Medical Officer at Memorial Sloan Kettering Cancer Center (MSK), New York, USA, where she holds the Scott M. and Lisa G. Stuart Chair. She served as chair of the Department of Neurology from 1997 to 2018, and co-founded MSK's Brain Tumor Center. Dr. DeAngelis specializes in brain cancer and the neurological complications of cancer treatment, including cognitive impairment and stroke, and her own research has focused on primary brain tumors. Dr. DeAngelis is an elected member of the National Academy of Medicine, a fellow of the American Neurological Association, and former Vice Chair of the Board. She is also a fellow of the American Academy of Neurology, which in 2019 awarded her the organization's highest honor, the Wartenberg Lecture.

Andrés José María Ferreri is the Deputy Director of the Haematology Unit and Director of the
Lymphoma Unit at the San Raffaele Scientific Institute, Milan, Italy, and President of the Italian Lymphoma Foundation (Fondazione Italiana Linfomi). Dr. Ferreri is fully devoted to research on lymphomas and is an international leader in the field of extranodal lymphomas.

SECTION 1: Neurological Conditions Associated with Malignant Haematological Diseases
1. Primary CNS Diffuse Large B-Cell Lymphoma, Christian Grommes, Lisa Giulino-Roth, Tejpal Gupta, and Andrés José María Ferreri
2. Immunodeficiency Associated Primary CNS Diffuse Large B-Cell Lymphoma, Samar Issa, Khê Hoang-Xuan, and Martina Deckert
3. Primary Vitreoretinal Lymphoma, Sara Steffanoni, Manabu Mochizuki, Tracy Batchelor, Denise Carbonell, Manfred Zierhut, and Judith Ferry
4. Rare Primary CNS Lymphomas, Christopher P. Fox, Motoo Nagane, and Vishakha Sovani
5. Histiocytic Tumours of the Central Nervous System, Oussama Abla and Jennifer Picarsic
6. Neurological Complications of Myeloid Malignancies, Tali Siegal, Alexandra Benouaich-Amiel, and Osnat Bairey
7. Neurological Complications of Lymphoid Malignancies, Julia Wendler, Gerald Illerhaus, and Lakshmi Nayak
SECTION 2: Neurological Complications of The Treatments Used In The Management of Haematological Malignancies
8. Neurological Complications of Medical Therapies in Haematological Malignancies, Joachim M. Baehring and Carole Soussain
9. Neurological Complications of Cell Therapies in Haematological Malignancies, Andreas F. Hottinger, Hervé Ghesquières, and Mehdi Touat
10. Neurological Complications of Radiation Therapies in Haematological Malignancies, Sebastian F. Winter and Jorg Dietrich
SECTION 3: Neurological Conditions and Complications Associated With Non-Malignant Haematological Disorders
11. Neurological Complications of Red Blood Cell Disorders, Joshua P. Klein and Natasha M. Archer
12. Neurological Complications of Platelet Disorders and Disorders of Coagulation, Sanam Baghshomali, Francisco E. Gomez, Aleksey Tadevosyan, and Monisha A. Kumar
13. Neurological Complications of White Blood Cell Disorders, Wolfgang Grisold, Teresa Calimeri, and Bianca D. Santomasso