Pharmacotherapy of Obesity

After three introductory chapters that deal with the general theme of obesity now regarded as a chronic disease this volume discusses the drugs sibutramine and orlistat, which are approved for long-term use in the US and in much of the rest of the world. The three final chapters discuss future drug targets, like the central nervous system and gut hormones, and how to influence energy expenditure and substrate utilization.

Why drugs?	p. 1
Some historical aspects of drug treatment for obesity	p. 11
Regulation of energy balance - towards rational drug design in obesity	p. 21
Intestinal lipase inhibitors	p. 47
Sibutramine	p. 59
The endocannabinoid system as a target for obesity treatment	p. 69
Using the body's natural signals - gut hormones	p. 81
Influencing energy expenditure and substrate utilisation	p. 101
Index	p. 117
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Pharmacotherapy of Obesity

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Table of Contents

Supplemental Materials