Precision Medicine in Oncology

A FRESH EXAMINATION OF PRECISION MEDICINE'S INCREASINGLY PROMINENT ROLE IN THE FIELD OF ONCOLOGY

Precision medicine takes into account each patient's specific characteristics and requirements to arrive at treatment plans that are optimized towards the best possible outcome. As the field of oncology continues to advance, this tailored approach is becoming more and more prevalent, channelling data on genomics, proteomics, metabolomics and other areas into new and innovative methods of practice. Precision Medicine in Oncology draws together the essential research driving the field forward, providing oncology clinicians and trainees alike with an illuminating overview of the technology and thinking behind the breakthroughs currently being made.

Topics covered include:

• Biologically-guided radiation therapy
• Informatics for precision medicine
• Molecular imaging
• Biomarkers for treatment assessment
• Big data
• Nanoplatforms

Casting a spotlight on this emerging knowledge base and its impact upon the management of tumors, Precision Medicine in Oncology opens up new possibilities and ways of working – not only for oncologists, but also for molecular biologists, radiologists, medical geneticists, and others.

Bulent Aydogan, PhD, Associate Professor, Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.

James Radosevich, PhD, Professor, Department of Oral Medicine and Diagnostic Sciences, University of Illinois at Chicago, Chicago, IL, USA.

List of Contributors

Preface

List of Abbreviations

Chapter 1 Genomic Strategies for Personalized Cancer Therapy

Chapter 2 Blood-based biomarkers for the diagnosis and prognosis of cancer

Chapter 3 Application of circulating cell free DNA for personalized cancer therapy

Chapter 4 Prognostic Implications of EGFR, p53, p16, cyclin D1, Bcl-2 in Head & Neck Squamous Cell Carcinoma (HNSCC)

Chapter 6 Predictive and prognostic markers for cancer medicine

Chapter 7 Dual Energy Imaging in Precision Radiation Therapy

Chapter 8 The role of Big Data in personalized medicine

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