Protein Misfolding Diseases Current and Emerging Principles and Therapies

An increasingly aging population will add to the number of individuals suffering from amyloid. Protein Misfolding Diseases provides a systematic overview of the current and emerging therapies for these types of protein misfolding diseases, including Alzheimer's, Parkinson's, and Mad Cow. The book emphasizes therapeutics in an amyloid disease context to help students, faculty, scientific researchers, and doctors working with protein misfolding diseases bridge the gap between basic science and pharmaceutical applications to protein misfolding disease.

Marina Ramirez-Alvarado is an Assistant Professor of Biochemistry and Molecular Biology at the Mayo Clinic. Despite being a young investigator, she is already a world leader in the study of molecular determinants of light chain amyloidosis, a rare misfolding disease. Jeffery W. Kelly is a Professor of Chemistry and Molecular and Experimental Medicine at the Scripps Research Institute. He is one of the leading authorities in the field of protein misfolding, with over 250 publications to his credit. Christopher M. Dobson is a Professor in the Department of Chemistry at the University of Cambridge. Dr. Dobson is a leading researcher studying the structural and biochemical bases of protein misfolding diseases and has over 500 publications.