Recent Advances in Cell Biology of Acute Leukemia : Impact on Clinical Diagnosis and Therapy

ISBN: 9780387564173 | 0387564179
Cover: Hardcover
Copyright: 12/1/1993

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Differentiation of Physiological and Malignant Cells of the B-Cell System	p. 1
Expression of B-Cell-Associated Antigens During B-Cell Ontogeny	p. 9
Normal and Aberrant T-Cell Receptor Protein Expression in T-Cell Acute Lymphoblastic Leukemia	p. 19
Flow Cytometric Analysis of Intracellular Myeloperoxidase and Lactoferrin in Leukemia Diagnosis	p. 31
Immunological, Ultrastructural and Molecular Features of Unclassifiable Acute Leukaemia	p. 41
Incidence and Clinical Relevance of Myeloid Antigen-Positive Acute Lymphoblastic Leukemia	p. 53
Myeloid-Associated Antigen Expression in Childhood Acute Lymphoblastic Leukemia	p. 67
Contribution of Electron Microscopy to the Classification of Minimally Differentiated Acute Leukemias in Children	p. 77
Molecular Cytogenetic Applications in Leukemias	p. 89
Cytogenetic Abnormalities Associated with Childhood Acute Myeloblastic Leukemia	p. 103
DNA Aneuploidy in Childhood Acute Lymphoblastic Leukemia: Relation to Clinical Determinants and Prognosis within Four Consecutive BFM Trials	p. 113
Clinical Significance of Cytogenetic Studies in Childhood Acute Lymphoblastic Leukemia: Experience of the BFM Trials	p. 123
Chromosomal Abnormalities in Adult Acute Lymphoblastic Leukemia: Results of the German ALL/AUL Study Group	p. 133
Molecular Genetic Techniques for Detection of Minimal Residual Disease in Acute Lymphoblastic Leukemia: Possibilities and Limitations	p. 149
Immunophenotypic and Immunogenotypic Detection of Minimal Residual Disease in Acute Lymphoblastic Leukemia	p. 157
Detection of Aberrant Antigen Expression in Acute Myeloid Leukemia by Multiparameter Flow Cytometry	p. 185
Detection of Residual Leukemic Cells in Adult Acute Lymphoblastic Leukemia by Analysis of Gene Rearrangements and Correlation with Early Relapses	p. 197
Interleukin-2-Based Immunotherapy in the Management of Minimal Residual Disease in Acute Leukemia Patients	p. 207
Preclinical Studies of T-Cell-Mediated Immune Responses Against Autologous Tumor Cells in Patients with Acute Leukemia	p. 215
Susceptibility of Human Leukemia Cells to Allogeneic and Autologous Lymphokine-Activated Killer Cells and Its Augmentation by Exposure of Leukemia Target Cells to Cytotoxic Drugs In Vitro and In Vivo	p. 223
Regulation of Protooncogenes and Cytokine Genes in Acute Lymphoblastic Leukemia	p. 239
Cellular Drug Sensitivity of Immunophenotypic Subgroups of Childhood Acute Lymphoblastic Leukemia	p. 249
Use of Clinical and Laboratory Features to Define Prognostic Subgroups in B-Precursor Acute Lymphoblastic Leukemia: Experience of the Pediatric Oncology Group	p. 257
Incidence and Prognostic Significance of Immunophenotypic Subgroups in Childhood Acute Lymphoblastic Leukemia: Experience of the BFM Study 86	p. 269
Incidence, Clinical and Laboratory Features, and Prognostic Significance of Immunophenotypic Subgroups in Acute Lymphoblastic Leukemia: The GEIL Experience	p. 283
Incidence and Prognostic Significance of Immunophenotypic Subgroups in Childhood Acute Lymphoblastic Leukemia: The Experience of the AIEOP Cooperative Study	p. 297
Mutations in the Regulatory Domains of bcr/abl-Positive Leukemias Detected by Solid-Phase Automated DNA Sequencing	p. 309
Clonal Analysis of n-ras Gene Activation in Acute Myeloid Leukemia	p. 315
Human Stem Cell Factor is a Growth Factor for Myeloid Leukemia Cells	p. 329
Morphologic Basis for the MIC Classification in Acute Myeloid Leukemia	p. 339
Molecular Genetics of the t(15;17) Translocation in Acute Promyelocytic Leukemia	p. 345
Immunophenotype of Hematologic Neoplasms with a Translocation t(8;21)	p. 361
Diagnostic and Prognostic Importance of Immunophenotyping in Adults with Acute Myeloid Leukemia	p. 369
Immunophenotype of Acute Myeloid Leukemia: Correlation with Morphological Characteristics and Therapy Response	p. 381
Multiparameter Analysis of Blast Cells in Patients with Acute Leukemia Following a Primary Myelodysplastic Syndrome	p. 393
Subject Index	p. 401
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