Familial Cancer and Prevention Molecular Epidemiology: A New Strategy Toward Cancer Control

, by Utsunomiya, Joji; Mulvihill, John J.; Weber, Walter

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ISBN: 9780471249375 | 0471249378
Cover: Hardcover
Copyright: 4/27/1999

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Up-to-date, authoritative, and comprehensive, Familial Cancer and Prevention is an important working resource for clinicians, cancer researchers, and epidemiologists.

Preface

xiii

Utsunomiya

Weber

Mulvihill

Contributors

xix

PART 1 OVERVIEWS

(18)

Introduction

(2)

Max M. Burger

The UICC Familial Cancer and Prevention Project

(2)

Walter Weber

Molecular Epidemiology of Human Cancer

(12)

S. Perwez Hussain

Curtis C. Harris

PART 2 GENERAL STRATEGIES AND EXPERIENCE

(2)

PART 2A LOGISTICS

(60)

From Nurse to Nodal Points: The Rationale of a Questionnaire and Database to Collect, Validate, and Exchange Information on Familial Cancer

(4)

Davide Brunetti

Walter Weber

Collecting Information About Familial Cancer

(8)

Walter Weber

Peter Mussio

Hans Stoll

Object-Oriented Computer Software Linking a Pedigree Drawing Application and an Advanced Relational Database: The ``Progeny'' System

(8)

Jose A. Bufill

David S. Deram

Michael Brammer

Research and Clinical Care Networks in Neurofibromatosis

(4)

Bruce R. Korf

Identification of Genetic Predispositions to Cancer: A Swiss Experience

(4)

Pierre O. Chappuis

Anne Murphy

Murielle Saugy

Phillippe Maillet

Pierre Hutter

Andre-Pascal Sappino

The Oxford Cancer Genetic Clinic: Experience of the First Seven Years

(8)

George R. Fraser

Family History-Based Screening for Colorectal Cancer

(6)

D. James B. St. John

Cancer Genetic Clinics: Characteristics of 552 Consultees Attending a Center in the South East of France

(6)

Francois Eisinger

Claire Julian-Reynier

Francoise Chabal

Yvette Aurran

Hagay Sobol

Presymptomatic Testing: Efficacy of a Clinical Risk Assessment Program

(6)

Brian A. Clark

Graham Casey

Linda Webster

Hereditary Tumor Registry in Korea

(4)

Jae-Gahb Park

PART 2B COUNSELING ISSUES

(68)

Ethical Issues in Precancer Screening: The Parallel With Huntington Disease

(6)

Donna L. Dickenson

Cancer-Predisposition Genetic Testing: Clinical and Prevention Implications

(10)

Gloria M. Petersen

Genetic Counseling of Cancer Patients and Their Relatives: Issues and Practices

(6)

Hansjakob Muller

A Nursing Perspective of Counseling Families in a Cancer Genetics Clinic

105

(6)

Audrey Ardern-Jones

The Nurse's Role in Decision Making in Familial Cancer

111

(6)

Hans Stoll

Familial Cancer: New and Evolving Challenges for Oncology Nurses and Their Patients

117

(4)

Mary C. Fraser

Counseling Issues: The Role of the Genetic Counselor

121

(10)

Elizabeth Gettig

Genetic Counseling and Its Ethical Issues in Japan

131

(6)

Koji Ohkura

Bioethical Concerns With Rights of Patients Receiving Genetic Tests

137

(6)

Kazumasa Hoshino

Use of Genetic Information by Private Insurers

143

(6)

Robert J. Pokorski

PART 3 SPECIFIC FAMILIAL CANCERS

149

(2)

PART 3A COLORECTAL CANCER

151

(2)

PART 3A.1 Familial Adenomatous Polyposis

153

(44)

Surgical Management of Familial Adenomatous Polyposis

153

(10)

J. Utsunomiya

N. Gondo

Extracolonic Symptoms of Familial Adenomatous Polyposis and Their Association With a Slow Acetylation Phenotype

163

(8)

Rodney J. Scott

Walter Taeschner

Urs A. Meyer

Hansjakob Muller

Desmoid Disease in Familial Adenomatous Polyposis

171

(6)

Karen P. Nugent

Chemoprevention of Colorectal Adenomas in Familial Adenomatous Polyposis With Low-Dose Suldinac: Clinical Outcome, Influence on Oncogenes, and Growth Factors: Interim Results of a Five-Year Study Course

177

(14)

Guenther Winde

Kurt W. Schmid

Oliver Muller

Helmut Bartsch

Hans Osswald

Interventional Trial for Cancer Prevention for Familial Adenomatous Polyposis

191

(6)

Hideki Ishikawa

Ikuko Akedo

Kazushige Iseki

Takaichiro Suzuki

Toru Otani

PART 3A.2 Hereditary Nonpolyposis Colorectal Cancer (HNPCC)

197

(76)

HNPCC: Genetics, Counseling, Natural History, Surveillance, and Management

197

(10)

Henry T. Lynch

Kevin Lin

Thomas Smyrk

Patrice Watson

Alan Thorson

Maniamparampil Shashidharan

Barbara Franklin

Beth Karr

Jane F. Lynch

Susan Tinley

Stephen Lanspa

Stephen J. Lemon

Trudy Shaw

Miguel A. Rodriguez-Bigas

Colorectal Cancer Prognosis in Hereditary Nonpolyposis Colorectal Cancer

207

(4)

Patrice Watson

Kevin Lin

Miguel A. Rodriguez-Bigas

Henry T. Lynch

Defining the Clinical Phenotype of Hereditary Nonpolyposis Colorectal Cancer

211

(4)

Nicholas E. Beck

Ian P.M. Tomlinson

Walter F. Bodmer

Evolution of Neoplasia in Hereditary Nonpolyposis Colorectal Cancer

215

(6)

Jeremy R. Jass

Controversial Issues in Hereditary Nonpolyposis Colorectal Cancer

221

(6)

Shozo Baba

Joshi Nakamura

Kokichi Sugano

Masayuki Yasutomi

Yusuke Nakamura

Benign Extracolonic Manifestations Associated With Hereditary Nonpolyposis Colorectal Cancer

227

(6)

G. Moslein

D. Schaid

R. Dozois

H.-D. Roher

S. McDonnell

S. Thibodeau

Prevention of Hereditary Nonpolypotic Colorectal Cancer: Molecular Testing of Known Family Members and Molecular Screening in Sporadic Colorectal Cancer Patients

233

(4)

Albert de la Chappelle

Molecular Biology of Hereditary Nonpolyposis Colorectal Cancer

237

(8)

Yasuhito Yuasa

Yoshimitsu Akiyama

An Automated Genetic Assay for Hereditary Nonpolyposis Colorectal Cancer

245

(6)

Robert B. Chadwick

Paula Kristo

Antonio Percesepe

Jianguo Chen

Jason Stein

Mel Kronick

Complex Genetic Predisposition to Cancer in an Extended HNPCC Kindred with an Ancestral hMLH1 Mutation

251

(8)

Pierre Hutter

Pierre O. Chappuis

Alexia Couturier

Veronique Antonioli

Jean-Marie Buerstedde

Surveillance and Management of Hereditary Nonpolyposis Colorectal Cancer

259

(8)

H.F.A. Vasen

G. Griffioen

J. Wijnen

H. Boonstra

R. Fodde

P. Meera Khan

Genetic Diagnosis and Management of Suspected Hereditary Nonpolyposis Colorectal Cancer

267

(6)

Jae-Gahb Park

Ying Yuan

Hye-Jung Han

PART 3A.3 Prevention

273

(70)

Prophylatic Colectomy in Hereditary Nonpolyposis Colorectal Cancer

273

(6)

Miguel A. Rodriguez-Bigas

Concerted Action Polyp Prevention: A Trial of Aspirin and/or Resistant Starch in People at Risk of Hereditary Colon Cancer

279

(6)

J. Burn

P.D. Chapman

D.T. Bishop

J. Mathers

Dietary Prevention of Colorectal Cancer

285

(6)

Finlay Macrae

Calcium in Cancer Prevention

291

(4)

Martin Lipkin

Chemo- and Dietary Prevention of Familial Cancer: From Theory to Practice

295

(8)

Arthur Schatzkin

Alisa Goldstein

Ernest Hawk

Protocol Concept: Phase I-II Multiple-Dose Safety and Efficacy Clinical Study of Nonsteroidal Anti-Inflammatory/COX-2 Based Regimen in Hereditary Nonpolyposis Colorectal Cancer (HNPCC) Patients and Asymptomatic Carriers

303

(12)

Patrick M. Lynch

The Impact of Living With Hereditary Colorectal Disease

315

(6)

Theresa Berk

Familial Colorectal Cancer in India: The Tata Memorial Hospital Experience

321

(8)

K.M. Mohandas

Gene-Diet Interactions and the High Colorectal Cancer Risk of Japanese Americans

329

(8)

Loic Le Marchandd

Lakshmi Sivaraman

Adrian A. Franke

Lisa M. Pierce

Ann Seifried

Annette Lum

Laurie J. Custer

Pratibha V. Nerurkar

Impact of Migration on the Phenotypes of Familial Cancer Clusters: A Study of Japanese Americans

337

(6)

Grant N. Stemmermann

A.M.Y. Nomura

J. Lee

PART 3B OTHER GASTROINTESTINAL CANCERS

343

(26)

Mutagen Sensitivity as a Predisposing Factor in the Identification of High-Risk Individuals in Oral Cancer Families

345

(8)

Ravindran Ankathil

Dinesh Roy

B. Vinod Kumar

G. Sunil Nayar

B. Jyothish

R. Chandini

F. Joseph

M. Krishnan Nair

Genetic Alterations in Esophageal Cancers

353

(8)

R. Montesano

C. Barnas

P. Taniere

T. Henn

O.A. Haas

P. Hainaut

Identification and Characterization of Families With Aggregation of Gastric Cancer

361

(2)

Atsushi Sasaki

Kazuya Shinmura

Haruhiko Sugimura

Naohito Yamaguchi

Jun Yokota

Ecogenetics of Pancreatic Cancer: A Registry of Cancer Families

363

(6)

John J. Mulvihill

Andrew Shapiro

Jason G. Emmick

Kerry E. Crowley

Carina J. Rodriguez

Michael G. Banke

Patrick L. McNamara

Sidney D. Finkelstein

Mohamed A. Virji

Christopher E. Aston

PART 3C ENDOCRINE CANCERS

369

(30)

Nationwide Survey and Analysis of the RET Proto-oncogene in Inherited Medullary Thyroid Carcinoma in Japan

371

(6)

Hiroshi Takami

Management of Hereditary Medullary Thyroid Carcinoma

377

(8)

Jeffrey F. Moley

Samuel A. Wells Jr.

Consequences of Specific RET Gene Mutations in Families With Multiple Endocrine Neoplasia Type 2

385

(8)

C.J.M. Lips

A.M.J. Moers

R.M. Landsvater

C. Schaap

G.H. Blijham

J.W.M. Hoppener

Th.M. Vroom

J.K. Ploos van Amstel

Recurrent Loss of Heterozygosity for Chromosome 1p in Siblings With Neuroblastoma

393

(6)

Gian Paolo Tonini

Achille Iolascon

Lucia Giordani

Katia Mazzocco

Bruno De Bernardi

Luisa Massimo

Massimo Conte

Giovanna Riccipetitoni

Crocifissa Lo Cunsolo

PART 3D BREAST CANCER

399

(48)

Recent Developments in the Genetic Epidemiology of Breast Cancer

401

(4)

Douglas Easton

Mutation Analysis of the BRCA1 and BRCA2 Genes in Japanese Breast Cancer Families

405

(4)

Yoshio Miki

Toyomasa Katagiri

Yusuke Nakamura

Mapping of Non-BRCA1/2 Breast Cancer Genes

409

(4)

Yin Yao Shugart

Dawn Teare

Carole Cour

Helene Renard

Colette Bonnardel

Alexandre Sibert

Douglas Easton

David Goldgar

Cancer Risk-Modifying Factors in BRCA1 or BRCA2 Mutation Carriers

413

(6)

Timothy R. Rebbeck

BRCA1-Associated Breast Cancer: Clinical, Morphological, and Molecular Features

419

(6)

Hagay Sobol

Dominique Stoppa-Lyonnet

Jean-Marc Guinebretiere

Brigitte Bressac-de Paillerets

Jean-Philippe Peyrat

Michel Longy

Jocelyne Jacquemier

Francois Eisinger

Daniel Birnbaum

A Novel 150K Marker for Early Human Mammary Carcinoma

425

(6)

Max M. Burger

Felix Bachmann

Rahel Banziger

Endocrine Approaches to Breast Cancer Prevention

431

(10)

Anthony Howell

Maria D. Bramley

Robert B. Clarke

Andrew D. Baildam

Elizabeth Anderson

Hereditary Breast Cancer: DNA-Based Genetic Counseling

441

(6)

Jane F. Lynch

Stephen J. Lemon

Carolyn Durham

Carrie Snyder

Patricia Tonin

Gilbert Lenoir

Olga Serova

Steven Narod

Caryn Lerman

Henry T. Lynch

PART 3E GENES FOR OTHER CANCERS

447

(76)

Diverse Cancers in Genetic Disorders: Case Series Compared

449

(6)

Robert W. Miller

Progress in the Diagnosis and Management of Neurofibromatosis

455

(6)

Bruce R. Korf

The NF2 Tumor Suppressor Gene

461

(6)

Brigitte Deguen

Marco Giovanni

Michiko Niwa-Kawiatika

Estelle Brault

Laurence Goutebroze

Gilles Thomas

Tuberous Sclerosis

467

(8)

David J. Kwiatkowski

Cancer Genetics of the Tuberous Sclerosis (TSC2) Gene Mutant

475

(6)

Okio Hino

Toshiyuki Kobayashi

Kenji Orimoto

Shinji Urakami

Tomokazu Fukuda

Nobuo Satake

Yokihiko Yamashita

Dilemmas in Predictive Gene Testing in Li-Fraumeni Syndrome: Experience with a Large Kindred

481

(4)

Robert J. McKinlay Gardner

Mary-Anne Young

Peter G. Bardy

Keith A. Byron

Genetic Studies of Retinoblastoma in India

485

(8)

I.C. Verma

V. Sharma

T.S. Sarkar

M. Kabra

L.S. Arya

N.A. Manjunath

Genetics Update: Cutaneous Malignant Melanoma and Melanocytic Nevi

493

(8)

Mark H. Greene

Xeroderma Pigmentosum: Diagnosis, Registration, and Skin Cancer Prevention

501

(6)

Kenneth H. Kraemer

Werner Syndrome: Adult Progeria With Cancer-Prone Inheritance

507

(8)

Makoto Goto

Yuichi Ishikawa

Haruo Sugano

Yasuhiro Furuichi

Robert W. Miller

Hereditary Multiple Exostoses and Cancer Risk

515

(8)

Daniel E. Porter

A.H.R.W. Simpson

PART 4 WORKSHOP REPORTS

523

(10)

UICC Molecular Biology Workshop Report

525

(6)

Rodney J. Scott

Workshop Report 1

531

(2)

Curtis C. Harris

PART 5 POSTER SESSIONS

533

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Familial Cancer and Prevention Molecular Epidemiology: A New Strategy Toward Cancer Control

Summary

Author Biography

Table of Contents

Supplemental Materials