The Treatment of Epilepsy

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ISBN: 9780683092851 | 0683092855
Cover: Hardcover
Copyright: 1/1/1997

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Contributing Authors	p. xiii
Foreword	p. xxiii
Preface	p. xxv
Basic Mechanisms of Epileptogenesis
Cellular Aspects of Epileptogenesis
Basic Cellular Neurophysiology	p. 3
Neurotransmitters and Receptors	p. 25
Mechanisms of Epileptogenesis and Experimental Models of Seizures	p. 33
Neuronal Migration Disorders: Developmental and Neuroanatomic Aspects
Brain Developmental Milestones and Pathologic Correlation	p. 45
Cerebral Dysgenesis and Epilepsy	p. 65
Cortical Anatomy: Normal and Abnormal Sulcal and Gyral Patterns	p. 79
Hippocampal Sclerosis: Neuroanatomic and Neurophysiologic Aspects
Normal Hippocampal and Temporal Anatomy	p. 93
Hippocampal Sclerosis: Pathology, Electrophysiology, and Mechanisms of Epileptogenesis	p. 105
Genetics and Epidemiology
Genetic Aspects of Epilepsy	p. 115
The Epidemiology of Epilepsy	p. 131
Remission, Intractability, Mortality, and Comorbidity of Seizures	p. 139
Basic Principles of Electroencephalography
Neurophysiologic Basis of the Electroencephalogram	p. 149
Polarity, Localization, and Field Determination in Electroencephalography	p. 165
Clinical Use of the Electroencephalogram in the Diagnosis of Epilepsy	p. 193
Computer-Assisted Data Collection and Analysis	p. 209
Electroencephalographic Atlas of Epileptiform Abnormalities	p. 225
Epileptic Seizures and Syndromes
Epileptic Seizures
Classification of Seizures	p. 287
Proposal for Revised Clinical and Electrographic Classification of Epileptic Seizures: Commission on Classification and Terminology of the International League Against Epilepsy	p. 291
Epileptic Auras	p. 299
Complex Partial Seizures	p. 309
Focal Motor Seizures and Epilepsia Partialis Continua	p. 329
Supplementary Sensorimotor Area Seizures	p. 345
Absence Seizures	p. 357
Generalized Tonic-Clonic Seizures	p. 369
Myoclonic Seizures	p. 395
Tonic and Atonic Seizures	p. 405
Infantile Spasms	p. 415
Epileptic Syndromes
Classification of the Epilepsies	p. 453
Proposal for Revised Classification of Epilepsies and Epileptic Syndromes: Commission on Classification and Terminology of the International League Against Epilepsy	p. 457
Symptomatic Focal Epilepsies	p. 467
Idiopathic and Benign Partial Epilepsies	p. 475
Childhood and Juvenile Absence Epilepsies	p. 485
Juvenile Myoclonic Epilepsy	p. 491
The Progressive Myoclonus Epilepsies	p. 509
Symptomatic Generalized Epilepsy and Lennox-Gastaut Syndrome	p. 525
Epilepsy with Reflex Seizures	p. 537
Less Common Epilepsy Syndromes	p. 551
Seizures in Special Clinical Settings
Neonatal Seizures	p. 577
Febrile Seizures	p. 601
Posttraumatic Epilepsy	p. 609
Brain Tumors and Epilepsy	p. 615
Epilepsy in the Setting of Neurocutaneous Syndromes	p. 627
Epilepsy in the Setting of Inherited Metabolic and Mitochondrial Disorders	p. 637
Seizures Associated with Nonneurologic Medical Conditions	p. 657
Catamenial Epilepsy and Issues of Fertility, Sexuality, and Reproduction	p. 671
Status Epilepticus	p. 681
Differential Diagnosis of Epilepsy
Psychogenic Seizures	p. 699
Other Nonepileptic Paroxysmal Disorders	p. 705
Antiepileptic Medications
General Principles of Antiepileptic Drug Therapy
Antiepileptic Drug Development	p. 719
Pharmacokinetics and Pharmacodynamics of Antiepileptic Drugs	p. 729
Pharmacokinetics in Infancy, Childhood, and Adolescence	p. 741
Initiating Drug Therapy	p. 759
Long-Term Therapy with Antiepileptic Drugs	p. 769
Treatment of Epilepsy During Pregnancy	p. 775
Treatment of Epilepsy in the Elderly	p. 787
Treatment of Epilepsy in the Setting of Renal and Liver Disease	p. 795
Discontinuting Antiepileptic Drug Therapy	p. 811
Specific Antiepileptic Medications and Other Therapies
Carbamazepine and Oxcarbazepine	p. 821
Valproate	p. 843
Phenytoin and Fosphenytoin	p. 853
Phenobarbital and Primidone	p. 869
Ethosuximide	p. 881
Benzodiazepines	p. 893
Gabapentin	p. 915
Lamotrigine	p. 933
Topiramate	p. 939
Tiagabine	p. 947
Felbamate	p. 953
Vigabatrin	p. 61
Adrenocorticotropin and Steroids	p. 969
Newer Antiepileptic Drugs	p. 977
Less Commonly Used Antiepileptic Drugs	p. 985
The Ketogenic Diet	p. 1001
Vagus Nerve Stimulation	p. 1007
Epilepsy Surgery
Identification of Candidates and Presurgical Evaluation
Recognition of Potential Surgical Candidates and Video Electroencephalography Evaluation	p. 1019
MRI Techniques in the Evaluation for Epilepsy Surgery	p. 1031
The Intracarotid Amobarbital Procedure	p. 1043
Metabolic and Functional Neuroimaging	p. 1053
Intracranial Electroencephalography and Localization Studies	p. 1067
Epilepsy Surgery in Specifics Settings
Selection of Candidates for Temporal Resection	p. 1077
Selection of Candidates for Extratemporal Resection	p. 1095
Resection for Epilepsy in the Setting of a Focal Lesion on MRI	p. 1115
Resection for Epilepsy in the Setting of a Nonlocalizing MRI	p. 1135
Hemispherectomy	p. 1147
Epilepsy Surgery in Infants and Children	p. 1161
Corpus Callosotomy and Multiple Subpial Transection	p. 1175
New Techniques: Gamma Knife	p. 1185
Deep Brain Stimulation for Epilepsy	p. 1193
Outcome and Complications of Epilepsy Surgery	p. 1197
Psychosocial Aspects of Epilepsy
Cognitive Effects of Epilepsy and Antiepileptic Medications	p. 1215
Psychiatric Aspects of Epilepsy	p. 1227
Quality of Life with Epilepsy	p. 1243
Legal Aspects of Epilepsy	p. 1251
Indications for Antiepileptic Drugs Sanctioned by the United States Food and Drug Administration	p. 1257
Subject Index	p. 1259
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The Treatment of Epilepsy

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