Workbook for Organic Synthesis Strategy and

This workbook accompanies Organic Synthesis: Strategy and Control, the bestselling advanced organic textbook Provides a complete course for advanced organic students and includes a graded set of problems, solutions and discussions to illustrate and develop the themes of each of the chapters in the textbook

Dr Paul Wyatt, School of Chemistry, University of Bristol, Bristol
Dr Wyatt is Director of Undergraduate Studies for the School of Chemistry at Bristol University and also Director of BRISTOL ChemLabS - a HEFCE Centre for Excellence in Teaching & Learning.

Dr Stuart Warren, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge
Dr Warren is the author of the bestselling textbooks Organic Synthesis: The Disconnection Approach (Wiley) and Organic Synthesis (OUP)

Preface
Introduction: Selectivity.
Planning Organic Syntheses: Tactics, Strategy and Control
Chemoselectivity
Regioselectivity: Controlled Aldol Reactions
Stereoselectivity: Stereoselective Aldol Reactions
Alternative Strategies for Enone Synthesis
Choosing a Strategy: The Synthesis of Cyclopentenones
Making Carbon-Carbon Bonds.
The Ortho Strategy for Aromatic Compounds
?-Complexes of Metals
Controlling the Michael Reaction
Specific Enol Equivalents
Extended Enolates
Allyl Anions
Homoenolates
Acyl Anion Equivalents
CarbonûCarbon Double Bonds.
Synthesis of Double Bonds of Defined Stereochemistry
Vinyl Anions
Electrophilic Attack on Alkenes
Vinyl Cations
Allyl Alcohols: Allyl Cation Equivalents (and More)
Stereochemistry.
Control of Stereochemistry ù Introduction
Diastereoselectivity
Resolution
The Chiral Pool: Asymmetric Synthesis with Natural Products as Starting Materials
Asymmetric Induction I: Reagent-Based Strategy
Asymmetric Induction II: Asymmetric Catalysis: Formation of CûO and CûN Bonds
Asymmetric Induction III: Asymmetric Catalysis: Formation of CûH and CûC Bonds
Asymmetric Induction IV: Substrate-Based Strategy
Kinetic Resolution
Enzymes: Biological Methods in Asymmetric Synthesis
New Chiral Centres from Old: Enantiomerically Pure Compounds & Sophisticated Syntheses
Strategy of Asymmetric Synthesis
Functional Group Strategy.
Functionalisation of Pyridine
Oxidation of Aromatic Rings and of Enol(ate)s
Functionality and Pericyclic Reactions: Nitrogen Heterocycles by Cycloadditions and Sigmatropic Rearrangements
Synthesis and Chemistry of Azoles and other Heterocycles with Two or more Heteroatoms
Tandem Organic Reactions
Index
Table of Contents provided by Publisher. All Rights Reserved.

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Workbook for Organic Synthesis Strategy and Control

Summary

Author Biography

Table of Contents

Supplemental Materials