Muscular Dystrophy

Katherine Bushby and Louise Anderson assemble an outstanding collection of key techniques for the analysis of DNA and protein from patients suspected to suffer from muscular dystrophy. Each method is highly detailed to ensure success and is presented by a hands-on expert. The various DNA techniques focus on both the X-linked muscular dystrophies and the autosomal recessive muscular dystrophies. The protein methods include expression analysis, multiplex western blot analysis, immunocytochemical analysis, and reviews of immunological reagents and of amplification systems. Comprehensive and highly practical, Muscular Dystrophy: Methods and Protocols offers today's diagnostic laboratories, basic and medical researchers, and clinicians an authoritative collection of tools that will serve as exacting diagnostic tools as well as greatly empowering research on the novel therapeutics now beginning to emerge.

Louise V. B. Anderson: Department of Neurobiology, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, UK Egbert Bakker: Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands Rita J. Balice-Gordon: Department of Biochemistry and Molecular Biology, University of Southern California, Los Angeles, CA Rumaisa Bashir: Department of Molecular Genetics, Biology of Disease, University of Durham, Thornaby, Stockton-on Tees, UK Jacques Beckmann: Genethon, Evry, France Carsten G. Bonnemann: Department of Pediatrical Cardiology, Center for Child Medicine, Georg-August-Universitat Gottingen, Gottingen, Germany Robert H. Brown, Jr.: MDA Clinic, Massachusetts General Hospital, Boston, MA Katharine M. D. Bushby: Department of Human Genetics, School of Biochemistry and Genetics, University of Newcastle Upon Tyne, Newcastle upon Tyne, UK Ann Curtis: Department of Molecular Genetics, School of Biochemistry and Genetics, University of Newcastle Upon Tyne, Newcastle upon Tyne, UK Johan T. den Dunnen: MGC-Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands C. de Toma: Laboratiore de Biochimie et Genetique Moleculaire, Paris, France George Dickson: Division of Biochemistry, School of Biological Sciences, University of London, Egham, Surrey, UK Jonathan K. Dore: Regional Genetic Service, St. Mary's Hospital, Manchester, UK Matthew G. Dunckley: Division of Biochemistry, School of Biological Sciences, University of London, Egham, Surrey, UK Mark Evans: Hutzel Hospital, Detroit, MI Rune R. Frants: Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands David Gardner-Medwin: Flocktons, Heddon on the Wall, Northumberland, UK James Giron: Children's Research Institute, Department of Molecular Genetics, Washington, DC Pascale Guicheney: CRVA-Department Gencell, France Daisy Haggerty: Department of Molecular Genetics, School of Biochemistry and Genetics, University of Newcastle Upon Tyne, Newcastle Upon Tyne, UK Ruth Harrison: Department of Human Genetics, School of Biochemistry and Genetics, University of Newcastle Upon Tyne, Newcastle upon Tyne, UK Anne Helbling-Leclerc: CRVA-Department Gencell, France Eric P. Hoffman: Children's Research Institute, Department of Molecular Genetics, Washington, DC Marc Jeanpierre: Laboratoire de Biochimie Genetique, Paris, France Margaret A. Johnson: Department of Neurology, Medcial School, University of Newcastle upon Tyne, Newcastle upon Tyne, UK Helen M. Kingston: Regional Genetic Service, St. Mary's Hospital, Manchester, UK Louis M. Kunkel: Division of Genetics, Departments of Neurology, The Childrens' Hospital, Boston, MA Qui Lu: Neuromuscular Unit, Royal Postgraduate School, Hammersmith Hospital, London, UK Vincenzo Nigro: Istituto di Patologia Generale e Oncologia, Seconda Universita Degli, Studi di Napoli, Napoli, Italy Maria Rita Passos-Bueno: Instituto de Biologia, Universidade de Sao Paulo, Sao Paulo, Brazil Frederica Piccolo: Laboratiore de Biochimie et Genetique Moleculaire, Paris, France Sita Reddy: Department of Biochemistry and Molecular Biology, University of Southern California, Los Angeles, CA Mark M. Rich: Department of Biochemistry and Molecular Biology, University of Southern California, Los Angeles, CA Isabelle Richard: Genethon, Evry, France Caroline A. Sewry: Neuromuscular Unit, Royal Postgraduate School, Hammersmith Hospital, London, UK Daniela Toniolo: Istituto di Genetica Biochimica ed Evoluzionistica, Pavia, Italy Silvere M. van der Maarel: Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands Mariz Vainzof: Instituto de Biologia, Universidade de Sao Paulo, Sao Paulo, Brazil Mayana Zatz: Instituto de Biologia, Universidade de Sao Paulo, Sao Paulo, Brazil