The Activities of Bacterial Pathogens in Vivo

, by Smith, Harry; Dorman, Charles J.; Dougan, G.; Holden, D. W.; Williams, P.

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ISBN: 9781860942723 | 1860942725
Cover: Hardcover
Copyright: 12/1/2001

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Describes the methods and shows how they, and a recent surge in conventional studies, are shedding light on the activities of bacterial pathogens in vivo. Discusses bacterial and host factors that operate in vivo to cause illness, showing how phenomena recognized in vitro relate to behavior in vivo, indicating how it might be obtained.

Preface

Introduction

Questions about the Behaviour of Bacterial Pathogens in Vivo

(36)

H. Smith

DNA Topology and Adaptation of Salmonella typhimurium to an Intracellular Environment

(22)

D. G. Marshall

C. J. Dorman

F. Bowe

C. Hale

G. Dougan

New Methods for Studying Bacterial Behaviour in Vivo

(138)

The Pathogenesis of Shigella flexneri Infection: Lessons from in Vitro and in Vivo Studies

(32)

D. J. Philpott

J. D. Edgeworth

P. J. Sansonetti

Detection and Analysis of Gene Expression During Infection by in Vivo Expression Technology

(32)

D.S. Merrell

A. Camilli

Measurement of Bacterial Gene Expression in Vivo

127

(28)

I. Hautefort

J. C. D. Hinton

Identification and Analysis of Bacterial Virulence Genes in Vivo

155

(25)

K. E. Unsworth

D. W. Holden

Salmonella Interactions with Host Cells: In Vitro to in Vivo

180

(19)

B. B. Finlay

J. H. Brumell

Impact of the New Methods

199

(82)

In Vivo Gene Expression and the Adaptive Response: From Pathogenesis to Vaccines and Antimicrobials

201

(25)

D. M. Heithoff

R. L. Sinsheimer

D. A. Low

M. J. Mahan

Challenge of Investigating Biologically Relevant Functions of Virulence Factors in Bacterial Pathogens

226

(34)

R. Moxon

C. Tang

Virulence Gene Regulation Inside and Outside

260

(21)

V. J. DiRita

N. C. Engleberg

A. Heath

A. Miller

J. A. Crawford

R. Yu

Evidence for Operation in Vivo of Aspects of Pathogenicity Revealed by Recent Work in Vitro: Potential Use of New Methods

281

(114)

Quorum Sensing and the Population-dependent Control of Virulence

283

(34)

P. Williams

M. Camara

A. Hardman

S. Swift

V. J. Hope

K. Winzer

B. Middleton

D. I. Pritchard

B. W. Bycroft

D. Milton

Type III Secretion: A Bacterial Device for Close Combat with Cells of Their Eukaryotic Host

317

(32)

G. R. Cornelis

Evolution of Microbial Pathogens

349

(25)

J. Morschhauser

G. Kohler

W. Ziebuhr

G. Blum-Oehler

U. Dobrindt

J. Hacker

The Immune Responses to Bacterial Antigens Encountered in Vivo at Mucosal Surfaces

374

(21)

G. Dougan

M. Ghaem-Maghami

D. Pickard

G. Frankel

G. Douce

S. Clare

S. Dunstan

C. Simmons

Index

395

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The Activities of Bacterial Pathogens in Vivo

Summary

Table of Contents

Supplemental Materials