Pituitary Disorders Diagnosis and Management

Do you want to be up to date on the latest concepts of diagnosis and treatment of patients suffering from disorders of the pituitary gland?

Are you looking for an expert guide to the best clinical management?

If so, this is the book for you, providing a full analysis of pituitary disorder management from acromegaly to Addison’s Disease; from Cushing’s Disease to hypopituitarism; from hormone disorders to hormone replacement 

Well-illustrated throughout and with contributions from leading specialists in pituitary disease, inside you’ll find comprehensive and expert coverage, including:

• Diagnosing pituitary disease
• Management options for each disorder
• Complications that can occur
• Psychological and psychosocial effects of pituitary disease
• What outcomes  you and your patients can expect over the long term
• Current research and clinical trials related to pituitary disease

Pituitary Disorders: Diagnosis and Management is the perfect clinical tool for physicians and health care providers from many related disciplines, and an essential companion for the best quality management of pituitary patients.

Sylvia Asa, MD, PhD, Clinical Department Head, Department of Laboratory Medicine and Pathobiology, University of Toronto, University Health Network and Ontario Cancer Institute, Toronto, Canada.

Edward R. Laws, MD, FACS, Director, Pituitary/Neuroendocrine Center, Department of Neurosurgery, Brigham & Women's Hospital, Harvard University, Boston, Massachusetts, USA.

Shereen Ezzat, FACO, FRCPC, MD, Professor of Medicine & Oncology Head, Endocrine Oncology Site Group, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada.

Linda Rio, MA, MFT, Pituitary Network Association, Los Angeles, California, USA.

List of Contributors, xxx

Introduction
Robert Knutzen

SECTION 1: OVERVIEW 

1 The Endocrine System
Sylvia L. Asa and Shereen Ezzat

2 Signs and Symptoms of Pituitary Disease Physical
Eva Fernandez-Rodriguez, Ignacio Bernabeu and Felipe F. Casanueva

Emotional
Eva N. Kassi, Gregory A. Kaltsas, George P. Chrousos

Psychosocial Aspects
Valerie Golden

SECTION 2: DISORDERS 

3 Acromegaly
Shereen Ezzat

4 Secondary Adrenal Insufficiency
Tobias Else, Richard J. Auchus

5 Adult Growth Hormone Deficiency
T. Brooks Vaughan III, Kristen O Riley, Lewis S Blevins Jr.

6 Pituitary Carcinoma
Sylvia L. Asa

7 Craniopharyngioma
Jessica K. Devin

8 Cushing’s Syndrome
Lewis S. Blevins, Jr.

9 Empty Sella Syndrome
Michael C. Oh and Manish K. Aghi

10 Familial pituitary adenomas
Laura C. Hernández-Ramírez, Márta Korbonits

11 FSH and LH Secreting Tumors
Bahram Khazai, Ronald S. Swerdloff and Christina Wang

12 Hypopituitarism
Klara J. Rosenquist and Ursula B. Kaiser

13 Clinically Nonfunctioning Pituitary Adenomas
Brandon A. Miller, Adriana G. Ioachimescu, Nelson M. Oyesiku

14 Prolactinoma
Luis Sobrinho

15 Rathke’s Cleft Cysts
Seunggu J. Han, Arman Jahangiri, Manish K. Aghi

16 Thyroid Hormone Deficiency
Whitney W. Woodmansee

17 Thyroid Stimulating Hormone Secreting Tumor
A Lania, L Persani, Paolo Beck-Peccoz

18 Pituitary disorders – specific issues for women
Maria Fleseriu, Christine G.Yedinak,Jessica Brzana and Shirley McCartney

19 Hypogonadism and male sexual function. 
Prasanth N. Surampudi, Christina Wang and Ronald Swerdloff

20 Specific to Children
Kathryn Pade and Mitchell E. Geffner

SECTION 3: DIAGNOSING PITUITARY DISORDERS
 
21 Physical examination
Laurence Katznelson

22 Pituitary Endocrine Function Testing
Shereen Ezzat

SECTION 4: TREATMENT OF PITUITARY DISORDERS
 
23 Medical management of pituitary adenomas
Paolo Cappabianca, Daniel M. Prevedello, Michelangelo de Angelis, Andressa Bornschein, Leo
F. S. Ditzel Filho, Domenico Solari, Ricardo L. Carrau, Felice Esposito, Danielle de Lara,  Luigi M. Cavallo,  Annamaria Colao

24 Surgical Pure endoscopic transsphenoidal surgery
Gautam U. Mehta, John A. Jane, Jr

Open transcranial approaches to the sella
Ian F. Dunn

Endoscopic Skull Base Approaches
Tong Yang and Theodore H. Schwartz

Transnasal Endoscope-Assisted Transsphenoidal Approach for Pituitary Tumors
Huy T. Duong and Daniel F. Kelly

25 Stereotactic Radiosurgery for Pituitary Adenomas
Brian J. Williams, Stephen J. Monteith, Jason P. Sheehan

26 Hormone Replacement Therapy Growth Hormone Deficiency in Adults
Joseph A.M.J.L. Janssen and Aart Jan van der Lely

Growth Hormone Deficiency in Children
Alan D. Rogol

Pituitary Hormone Replacement in Women
Adriana G. Ioachimescu 

SECTION 5: COMPLICATIONS THAT ACCOMPANY PITUITARY DISEASE  

27 Complications of pituitary disease

Cardiac complications of pituitary diseases
Ludovica F. S. Grasso, Alessia Cozzolino, Annamaria Colao

Cognitive dysfunction
Krystallenia I. Alexandraki, Gregory A. Kaltsas, George P. Chrousos

Diabetes insipidus
Marco Faustini-Fustini and Giorgio Frank

Headaches
Paul B. Rizzoli

Obesity
Andrea L. Utz

Osteoporosis
Andrea L. Utz

Permanent hormone deficiency
Andrea L. Utz

Visual Deficits Caused By Pituitary Tumors
Sashank Prasad

SECTION 6: GENERAL PSYCHOLOGICAL AND PSYCHOSOCIAL EFFECTS  

28 General Psychological and Psychosocial Effects of Pituitary Disorders
Valerie Golden

SECTION 7: LONG TERM: WHAT YOU AND YOUR PATIENTS CAN EXPECT 
 
29 Living with Pituitary Disease
Jessica K. Devin

SECTION 8: RESEARCH AND CLINICAL TRIALS
 
30 Research and Clinical Trials
Brittany P. Sumerel and Anthony P. Heaney

SECTION 9: RESOURCES 

31 The Fundamentals of Pituitary Pathology
Sylvia L. Asa

Glossary of Pituitary Related Disorders
Pejman Cohan

Index

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