Rudolph's Pediatrics, 22nd Edition
, by Rudolph, Colin; Rudolph, Abraham; Lister, George; First, Lewis; Gershon, Anne
- ISBN: 9780071497237 | 0071497234
- Cover: Hardcover
- Copyright: 4/8/2011
The landmark pediatrics reference-now extensively updated in full color and more clinically relevant than everRudolph's Pediatricshas virtually defined the pediatric field for over a century, becoming one of the most important and well-respected pediatrics texts ever published. Renowned for its balance of clinical features and treatment of disease with underlying biological principles, this classic sourcebook has helped generations of pediatricians optimize their care of infants, children, and adolescents. The 22nd edition ofRudolph's Pediatricscontinues a long tradition of adapting its content to changes in our understanding of children's health and disease, providing an up-to-date, in-depth survey of pediatric medicine unmatched by any other text. With its algorithmic approach to pediatric systems, the book facilitates the diagnosis and treatment of both common and uncommon pediatric illnesses; and it reflects new technologies and advances in molecular medicine that continue to evolve with current thinking about normal childhood development and pediatric disease processes.NEW TO THIS EDITION: New four-color design adds depth and clarity to the book's content Over 900 full-color, high-quality images and illustrations A reorganized, reader-friendly format broken down into sections and chapters for easier navigation and reference New emphasis on the clinical management of the patient makes this the most practical edition to date New sections provide a timely overview of pediatric care fundamentals and an entirely revised discussion of health promotion and disease prevention Substantially revised sections cover key areas of pediatric study and practice, including infectious diseases, immunology, allergy, neoplastic disorders, the cardiovascular system, urinary complications, and more Greater use of tables and lists conveniently summarize need-to-know diagnostic and therapeutic information
Colin Rudolph, MD, PhD, Professor of Pediatrics, Pediatric Gastroenterology and Nutrition, Medical College of Wisconsin.
.Abraham Rudolph, MD, Professor Emeritus, Pediatric Cardiology, and Senior Staff, Cardiovascular Research Institute, University of California, San Francisco.
.Lewis First, MD, Chair, Department of Pediatrics, University of Vermont College of Medicine.
.George Lister, MD, Chair in Pediatrics, Professor in Pediatrics, University of Texas Southwestern Medical School.
.Anne A. Gershon, MD, Professor of Pediatrics, Director, Division of Pediatric Infectious Diseases, Columbia University College of Physicians and Surgeons.
Contributors
Preface
Acknowledgments
SECTION 1: FUNDAMENTALS OF PEDIATRICS
Section Editor: Thomas G. DeWitt
1. Role of the Pediatrician, Thomas G. DeWitt and Neal Halfon
2. Decision-Making: Use of Evidence-Based Medicine, Suresh Nagappan and Kenneth B. Roberts
3. Communication, Elizabeth A. Rider
4. Interviewing Techniques, Christopher F. Bolling
5. Systems of Practice and Office Management, Peter Margolis
6. Core Competencies, Theodore C. Sectish
7. Patient and Family-Centered Care, Jeffrey M. Simmons, Stephen E. Muething, and Kathleen L. Dressman
8. Disaster Preparedness, Janet M. Berreman and Linda Rudolph
9. Law, Ethics, and Clinical Judgment, Angela Roddey Holder
SECTION 2: HEALTH PROMOTION AND DISEASE PREVENTION
Section Editor: Eve R. Colson
Part 1: Health Maintenance Issues
10. Well-Child Care, Judith S. Shaw and Judith S. Palfrey
11. Child Development, Ilgi Ozturk Ertem and Carol Cohen Weitzman
12. Screening, Ada M. Fenick
13. Oral Heatlh Supervision, Ada M. Fenick and Linda P. Nelson
14. Complementary and Alternative Medicine (CAM), Anju Sawni
15. Culture and Pediatric Practice, Sakena Abedin
16. Gay and Lesbian Parents, Cindy M. Schorzman and Melanie A. Gold
17. Environmental Pediatrics, Ruth A. Etzel
18. Travel Medicine, Joseph A. Zenel and Chandy C. John
Part 2: Managing Family Transition
19. Family Function and Birth of a Child, William I. Cohen
20. Foster Care and Adoption, Brad D. Berman and Carol Cohen Weitzman
21. Family Discord and Divorce, Michael Jellinek
22. Supporting the Grieving Child and Family, David J. Schonfeld
SECTION 3: NUTRITION
Section Editor: Praveen S. Goday
23. Normal Nutritional Requirements, Praveen S. Goday
24. Breast-Feeding, Jane Morton and Ruth A. Lawrence
25. Infant Formula and Complementary Foods, Margaret Kirby
26. Postdischarge Nutritional Management of the Premature Infant, Utpala G. Das
27. Nutritional Issues: Toddler to Adolescent, Margaret Kirby and Praveen S. Goday
28. Assessment of Nutritional Adequacy, Praveen S. Goday
29. Malnutrition and Refeeding, Praveen S. Goday
30. Poor Weight Gain, Karen A. Francolla and Praveen S. Goday
31. Approach to the Infant and Child with Feeding Difficulty, Richard J. Noel
32. The Overweight or Obese Child, Michelle Smith-Beckley and Brian M. Fidlin
33. Specialized Nutrition Support, Praveen S. Goday
34. Nutritional Access Devices, Lillian Sablan and Karen Sherry
SECTION 4: ABUSE, NEGLECT, VIOLENCE
Section Editor: John M. Leventhal
35. Child Maltreatment: Neglect to Abuse, John M. Leventhal and Andrea G. Asnes
36. Family and Community Violence, Renée Boynton-Jarrett and Robert Sege
37. Child Abuse Prevention: What Pediatricians Can Do, Wendy Gwirtzman and Howard Dubowitz
SECTION 5: NEWBORN
Section Editors: Alan H. Jobe and James M. Greenberg
Part 1: Care of the Newborn
38. Historical Perspectives, James G. Greenberg
39. Care of the Fetus, Alan H. Jobe
40. Fetal Disorders, Timothy M. Crombleholme and Foong-Yen Lim
41. Neonatal Mortality and Morbidity, Avroy A. Fanaroff
42. Delivery Room Resuscitation, Myra H. Wyckoff
43. Transitional Changes in the Newborn, David P. Carlton
44. Examination of the Newborn Infant, Joseph A. Zeneel
45. Postnatal Care and Observation, Anthony E. Burgos
Part 2: Infants at Risk
46. Multiple Births, James M. Greenberg
47. The Small-for-Gestational Age Infant, William W. Hay, Jr.
48. Infant of a Diabetic Mother, Heather Morein French and Rebecca A. Simmons
Part 3: Specific Neonatal Conditions
49. Approach to the Cyanotic Infant, Robin H. Steinhorn
50. Abnormalities of the Lungs, M. Grisel Galarza and Ilene R.S. Sosenko
51. Metabolic Abnormalities, William W. Hay, Jr.
52. Brain Abnormalities and Injuries, Seetha Shankaran and C. Michael Cotton
53. Hematologic Abnormalities and Jaundice, Henry C. Lee and Ashima Madan
Part 4: Disorders Specifically Related to Preterm Birth
54. Respiratory Distress Syndrome, Thomas N. Hansen and Samuel Hawgood
55. Patent Ductus Arteriosus and Ductus Venosus, Ronald I. Clyman
56. Hemodynamics, Nick Evans
57. Necrotizing Enterocolitis, Barbara Warner
58. Intraventricular Hemorrhage, Henrietta S. Bada
59. Bronchopulmonary Dysplasia, Alan H. Jobe
60. Emergencies, James M. Greenberg
61. Special Intensive Care, Thomas A. Parker
62. Outcomes of Preterm and Term Infants, Marilee C. Allen
SECTION 6: PRINCIPLES OF ADOLESCENT CARE
Section Editors: Charles E. Irwin, Jr., Mary-Ann Shafer, and Anna-Barbara Moscicki
Part 1: Growth and Development
63. Somatic Growth and Development, Charles E. Irwin, Jr.
64. Reproductive Growth and Development in the Female Adolescent, Melissa Slivka, Anna-Barbara Moscicki, and Mary-Ann Shafer
65. Reproductive Growth and Development in the Male Adolescent, David J. Breland and Mark L. Rubinstein
66. Psychological Development, Elizabeth M. Ozer and Charles E. Irwin, Jr.
67. The Adolescent Visit, Charles E. Irwin, Jr.
Part 2: Health Problems of Adolescents
68. Mortality, Elizabeth M. Ozer
69. Morbidity, Charles E. Irwin, Jr.
70. Sexual Behavior, Erica B. Monasterio
71. Substance Use and Abuse, Stephanie N. Crewe and Arik V. Marcell
Part 3: Mental Health Disorders in the Adolescent
72. Depression, Anxiety, and Other Disorders, Kim Peter Norman
73. Disorders of Eating, Kim Peter Norman, Sara M. Buckelew, and Andrea K. Garber
Part 4: Reproductive Health Problems
74. Breast Masses, Jennifer C. Edman and Mary-Ann Shafer
75. Scrotal Masses, David J. Breland and Mark L. Rubinstein
76. Menstrual Problems, Jennifer C. Edman and Mary-Ann Shafer
77. Intrauterine and Ectopic Pregnancy, Erica B. Monasterio and Mary-Ann Shafer
78. Contraception, Erica B. Monasterio and Mary-Ann Shafer
SECTION 7: DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS
Section Editor: Martin T. Stein
Part 1: General Concepts
79. Introduction to Developmental and Behavioral Pediatrics, Martin T. Stein
80. Fundamental Concepts of Child Development, W. Thomas Boyce and Jack P. Shonkoff
81. Brain Development and Behavior, Charles A. Nelson III
82. Standardized Developmental Screening and Assessment Instruments, Martin T. Stein
Part 2: Developmental Variation to Disorder
83. Crying in Infants, Ronald G. Barr and Takeo Fujiwara
84. Hyperactivity and Inattention, Martin T. Stein and Michael I. Reiff
85. Learning Problems, Michael I. Reiff and Martin T. Stein
86. Language Delay, James S. Andrews and Heidi M. Feldman
87. Difficult Behavior, Martin T. Stein
88. Anxiety, Denise A. Chavira
89. Repetitive Behaviors, Adrian D. Sandler
90. Gender Identity and Sexual Behavior, Kenneth J. Zucker
91. Developmental Delay, Nathan J. Blum
Part 3: Major Psychopathologic Disorders
92. Autistic Spectrum Disorders, Michael I. Reiff
93. Affective Disorders and Suicide, Laura Prager, Steven C. Schlozman,and Michael Jellinek
94. Pediatric Condition Falsification, Herbert Schreier
95. Childhood Schizophrenia, Fred R. Volkmar
Part 4: Psychosocial Context of Development and Behavior
96. Families in the 21st Century:An Introduction to Families, Laurie J. Baumann and Ruth E. K. Stein
97. Nonparental Childcare, Nerissa S. Bauer
98. Vulnerable Child Syndrome, Yi Hui Liu
99. Adaptation to Illness, David J. Schonfeld
100. Poverty, Homelessness, andSocial Disorganization, Barry S. Zuckerman and Megan Sandel
101. Resiliency in Children and Adolescents, Saul Levine
SECTION 8: THE ACUTELY ILL INFANT AND CHILD
Section Editors: Julio Pérez Fontán and George Lister
Part 1: Assessment of the Acutely Ill Infant and Child
102. Respiratory Distress and Failure, Julio Pérez Fontán
103. Decreased Perfusion and Circulatory Shock, George E. Lister
104. Acute Neurological Dysfunction, Susan T. Arnold
105. The Febrile Child, M. Douglas Baker and Jeffrey R. Avner
Part 2: Stabilization and Management of the Acutely Ill Infant and Child
106. Monitoring of Vital Function, George E. Lister
107. Vascular Access, Andreas A. Theodorou and Robert A. Berg
108. Cardiopulmonary Resuscitation, Mary Fran Hazinski
109. Life Support Systems, Julio Pérez Fontán
110. Stabilization and Transport, Deborah Lerner, George Lister, and Julio Pérez Fontán
111. Management of Cerebral Edema andElevated Intracranial Pressure, Steven G. Kernie
112. Perioperative Care, Desmond B. Henry
113. Pain Management and Sedation, Alan Farrow-Gillespie
114. Acute Metabolic Dysfunction, Ralph J. DeBerardinis
Part 3: Injuries and Untoward Events
115. Acute Inflammation, Clifford W. Bogue
116. Trauma, Burns, and Bites, Robert P. Foglia
117. Submersion Injury, Pamela J. Okada and M. Douglas Baker
118. Foreign-Body Aspiration, Margaret A. Kenna
119. Apparent Life-Threatening Events and SIDS, Michael J. Corwin
120. Toxic Ingestions and Exposures, Sing-Yi Feng, Collin S. Goto, and M. Douglas Baker
121. Heat Stress, Michael Apkon
122. Poisonous Bites and Stings, Dee Hodge III and Carl R. Baum
SECTION 9: THE CHRONICALLY ILL INFANT AND CHILD
Section Editors: Julio Pérez Fontán and George E. Lister
Part 1: The Changing Outlook of Chronic Illness in Childhood
123. Psychological and Behavioral Responses in Children and Their Families, Patricia J. Hicks
124. The Technology-Dependent Child, John B. Gordon, Sarah P. Brown, Jerie Beth Karkos, and Lynn A. D'Andrea
Part 2: Death and Dying in Childhood
125. Caring for Children Dying From Chronic Disease, Arthur R. Ablin
126. Hospice and Palliative Care, Julie Hauer, Barbara L. Jones, and Joanne Wolfe
127. Law, Ethics, and Caring Near the End of Life, Angela Roddey Holder
SECTION 10: TRANSPLANTATION
Section Editor: Patrick J. Healey
128. Pediatric Transplantation, Patrick J. Healey
129. Kidney Transplantation, Jodi M. Smith and Ruth A. McDonald
130. Liver Transplantation, Patrick J. Healey
131. Intestinal and Multivisceral Transplant, Simon Horslen
132. Heart Transplant, Beth D. Kaufman
133. Hematopoietic Cell Transplantation, Ann E. Woolfrey, Paul A. Carpenter, and Jean E. Sanders
SECTION 11: INHERITED DISORDERS OF METABOLISM
Section Editor: Jean-Marie Saudubray
Part 1: Inborn Errors of Metabolism
134. Principles of Inborn Errors of Metabolism, Jean-Marie Saudubray and Joe T.R. Clarke
Part 2: Disorders of Amino Acid (AA) and Organic Acid (OA) Metabolism
135. Hyperphenylalaninemias, Bernd Christian Schwahn
136. Disorders of the Tyrosine Metabolism, Bernd Christian Schwahn
137. Disorders of the Branched Chain Amino and Organic Acid Metabolism, Stephen I. Goodman and Jean-Marie Saudubray
138. Disorders of Sulfur-Containing Amino Acid Meteabolism, Bernd Christian Schwahn
139. Disorders of Glycine, Serine, and Proline Metabolism, Bernd Christian Schwahn
140. Disorders of Metabolism of Lysine, Hydrozylysine, and Related Compounds, Stephen I. Goodman
141. Disorders of Metabolism of Neurotransmitter Amino Acids, Jaak Jaeken
142. Disorders of Creatine and Ornithine Metabolism, Sylvia Stockler-Ipsiroglu
143. Disorders of Amino Acid Transport Across Cell Membranes, Kirsti Näntö-Salonen and Ollie Simell
144. Other Disorders of Amino Acid Metabolism, Jean-Marie Saudubray
145. Urea Cycle and Related Disorders, Mendel Tuchman, Uta Lichter-Konecki, and Mark L. Batshaw
Part 3: Inborn Errors of Water Soluble Vitamins
146. Introduction, Stephen I. Goodman
147. Vitamin B12 and Folic Acid, David Watkins and David S. Rosenblatt
148. Biotin Responsive Disorders, Stephen I. Goodman
149. Vitamin B6 and Vitamin B1 Responsive Disorders, Jean-Marie Saudubray
Part 4: Disorders of Fatty Acid Oxidation, Ketogenesis, and Ketolysis
150. Disorders of Fatty Acid Oxidation, Stephen I. Goodman
151. Disorders of Ketogenesis, Stephen I. Goodman
152. Disorders of Ketolysis, Stephen I. Goodman
153. Disorders of Leukotriene Synthesis andFatty Aldehyde Dehydrogenase, Stephen I. Goodman
Part 5: Carbohydrate Metabolism
154. Disorders of Glycogen Metabolism, Priya S. Kishnani and Yuan-Tsong Chen
155. Disorders of Galactose and FructoseMetabolism and Gluconeogenesis, Priya S. Kishnani and Yuan-Tsong Chen
156. Disorders of Pentose Phosphate Pathway, Priya S. Kishnani and Yuan-Tsong Chen
157. Disorders of Glucose Transporters, René Santer
Part 6: Disorders of Oxidative Phosphorylation and Pyruvate Oxidation
158. Respiratory Chain Disorders, Salvatore DiMauro
159. Disorders of Energy Metabolism, Juan M. Pascual and Salvatore DiMauro
Part 7: Organelle Related Disorders
160. Mucopolysaccharidosis, Glycoproteinosis,and Mucolipidosis, James Edmond Wraith
161. Sphingolipidoses, Joe T.R. Clarke
162. Peroxisomal Disorders, David Valle, Gerald V. Raymond, and Stephen J. Gould
163. Congenital Disorders of Glycosylation, Jaak Jaeken
Part 8: Disorders of Lipid and Bile Acid Metabolism
164. Disorders of Cholesterol Synthesis, Peter T. Clayton
165. Disorders of Bile Acid Synthesis, Peter T. Clayton
166. Disorders of Lipid and Lipoprotein Metabolism, Peter O. Kwiterovich, Jr.
Part 9: Disorders of Nucleic Acids, Heme Metabolism, and Metals Transport
167. Disorders of Heme Biosynthesis: The Porphyrias, Robert J. Desnick
168. Disorders of Purine and Pyrimidine Metabolism, Georges van den Berghe
169. Disorders of Metal Metabolism, Jean-Marie Saudubray
SECTION 12: CLINICAL GENETICS AND DYSMORPHOLOGY
Section Editors: John C. Carey and Michael J. Bamshad
Part 1: The Genetic Approach to Disorders of Children
170. Key Principles in Human Genetics, Michael J. Bamshad and Lynn B. Jorde
171. Multifactorial Inheritance, Lynn B. Jorde
172. Principles of Care, Claire O. Leonard
Part 2: Chromosomal Disorders
173. Human Cytogenetics, Sarah T. South and John C. Carey
174. Chromosome Disorders, John C. Carey
Part 3: Birth Defects, Malformations, and Syndromes
175. Birth Defects, Malformations, and Syndromes, John C. Carey and Michael J. Bamshad
176. Syndromes of Multiple CongenitalAnomalies/Dysplasias, John C. Carey
177. Craniofacial Disorders, Carrie Lyn Heike and Michael L. Cunningham
178. Approach to the Child with Birth Defects, John C. Carey and Michael J. Bamshad
179. Genetics Skeletal Disorders, John C. Carey and Michael J. Bamshad
180. Congenital Contractures, Michael J. Bamshad and John C. Carey
181. Connective Tissue Dysplasias, Alan Rope
182. Neurocutaneous Disorders, David H. Viskochil
183. Environmental Causes of Birth Defects, Elizabeth Balken, Marsha Leen-Mitchell, Lynn P. Martinez, and Julia A. Robertson
184. Disorders of Accelerated Aging, John C. Carey
185. Genetic Evaluation of Developmental Delay/Mental Retardation, Agatino Battaglia and John C. Carey
SECTION 13: IMMUNOLOGIC DISORDERS
Section Editor: Talal A. Chatila
186. Overview of the Immune System, Eli M. Eisenstein, Kathleen E. Sullivan, and Calvin B. Williams
187. Undue Susceptibility to Infection, Talal A. Chatila
188. Primary Immunodeficiencies, Talal A. Chatila
189. Complement Disorders, Patricia C. Giclas and Ashley A. Frazer-Abel
SECTION 14: ALLERGIC DISORDERS
190. Allergic Disease and Atopy, Talal A. Chatila
191. Clinical Aspects of Allergic Diseases, Maria Garcia-Lloret
192. Allergic Rhinitis and Conjunctivitis, Maria Garcia-Lloret
193. Anaphylaxis, Urticaria, and Angioedema, Marc A. Riedel
194. Food Allergy, Maria Garcia-Lloret
195. Insect Allergy, Maria Garcia-Lloret
196. Latex Allergy, Marc A. Riedel
197. Adverse Reactions to Drugs, Marc A. Riedel
SECTION 15: RHEUMATOLOGY
Section Editor: Robert P. Sundel
Part 1: General Principles in Rheumatology
198. Pathogenesis of Inflammatory and Autoimmune Disorders, Kathleen E. Sullivan
199. History and Physical Exam, Robert P. Sundel
200. Diagnostic Testing in Rheumatology, Peter A. Nigrovic
Part 2: Specific Rheumatologic Disorders
201. Juvenile Idiopathic Arthritis, Carol A. Wallace, David A. Cabral, and Robert P. Sundel
202. Spondyloarthropathies, David A. Cabral and Lori B. Tucker
203. Vasculitides, Karyl S. Barron
204. Systemic Lupus Erythematosus, Overlap Connective Tissue Diseases, and Mixed Connective Tissue Disease, Earl D. Silverman
205. Juvenile Dermatomyositis, Lisa G. Rider
206. Scleroderma, Francesco Zulian
Part 3: Systemic Syndromes in Rheumatology
207. Musculoskeletal Pain Syndromes, Yukiko Kimura
208. Chronic Fatigue Syndrome, David S. Leslie
209. Autoinflammatory Disorders, Peter J. Hashkes
SECTION 16: THE MUSCULOSKELETAL SYSTEM
Section Editor: John A. Herring
210. Growth and Development, John G. Birch
211. The Limping Child, Lawson A.B. Copley
212. Torsional and Angular Deformities, Karl E. Rathjen
213. Disorders of the Foot, Charles E. Johnston
214. Disorders of the Knee, John A. Herring
215. Developmental Dysplasia of the Hip, David A. Podeszwa
216. Disorders of the Neck and Spine, Daniel J. Sucato
217. Disorders of the Upper Extremity, Marybeth Ezaki
218. Injuries, Philip Wilson
219. Tumors, B. Stephens Richards
220. Neuromuscular Disorders, Lori A. Karol
221. Common Orthopedia Misses, John A. Herring
SECTION 17: INFECTIOUS DISEASES
Section Editors: Anne A. Gershon and Peter J. Hotez
Part 1: Principles of Infectious Disease
222. Bacterial Pathogenesis, Janet R. Gilsdorf and Carl F. Marrs
223. Bacteremia, Sepsis, and Septic Shock, Stephanie H. Stovall and Richard F. Jacobs
224. Viral Pathogenesis, Anne Moscona and Anne A. Gershon
225. Infection Control, Margaret C. Fisher
226. Diagnostic Approaches for Infectious Diseases, John C. Christenson and E. Kent Korgenski
227. Acute Fever without a Focus, Steven Black
228. Fever of Unknown Origin, Russell W. Steele
229. Fever and Infection in theImmunocompromised Patient, David B. Haslam and Jeffrey Scott McKinney
230. Therapy for Perinatal and Neonatal Infections, David W. Kimberlin, Debra L. Palazzi,and Richard J. Whitley
Part 2: Infections of Organ Systems
231. Bacterial Infections of the CentralNervous System, Thomas S. Murray and Robert S. Baltimore
232. Viral Infections of the Central Nervous System, John F. Modlin
233. Sexually Transmitted Infections, Loris Y. Hwang, Anna-Barbara Moscicki,and Mary-Ann Shafer
234. Bone, Joint, and Soft Tissue Infections, Robin B. Churchill and Blanca E. Gonzalez
235. Cardiac Infections, Janet A. Stockheim and Stanford T. Shulman
236. Gastrointestinal Infections, Matthew B. Laurens and Michael S. Donnenberg
237. Infections of the Liver, M. Kyle Jensen and Grzegorz Telega
238. Urinary Tract Infections, Keith M. Krasinski
239. Catheter-Associated Infections, Marc Foca
Part 3: Infections of the Respiratory System
240. Community-Acquired and BacterialPneumonia in Children, Stephen I. Pelton
241. Viral Respiratory InfectionsIncluding Influenza, J. Robert Honegger and Michael T. Brady
242. Fungal Respiratory Infections, Hana Hakim and Aditya H. Gaur
243. Infections of the Ear, Jerome O. Klein
Part 4: Treatment and Prevention of Infectious Diseases
244. Immunizations, Kristina A. Bryant
245. Antiviral Therapy,David K. Hong and Charles G. Prober
246. Antibacterial Therapy, David K. Hong and Charles G. Prober
247. Antifungal Therapy, Patricia M. Flynn
Part 5: Bacterial Infections
248. Actinomycosis, Nahed Abdel-Haq and Ashir Kumar
249. Anaerobic Infections, Ayesha Mirza and Mobeen H. Rathore
250. Clostridial Infections, Jose Zayas and Mobeen H. Rathore
251. Anthrax (Bacillus anthracis), Denis Bratcher
252. Arcanobacterium, Dennis L. Murray
253. Bacillus cereus
254. Brucellosis, Ziad M. Shehab
255. Burkholderia and Pseudomonas, Jane L. Burns
256. campylobacter Infections, Guillermo M. Ruiz-Palacios
257. Cat Scratch Disease, Moshe Ephros and Michael Giladi
258. Chancroid (Hemophilus ducreyi), Mary Allen Staat
259. Chlamydia, Navjyot K. Vidwan and Mary Allen Staat
260. Cholera, Chokechai Rongkavilit and Ashir Kumar
261. Diphtheria, Gary D. Overturf
262. Enterococci, Dwight A. Powell
263. Haemophilus influenzae, Mark R. Schleiss and Arnold L. Smith
264. Legionella Pneumonia, Lorry G. Rubin
265. Leptospirosis, Anne A. Gershon and Michael Katz
266. Listeriosis, Ziad M. Shehab
267. Lyme Disease, Michael A. Gerber
268. Moraxella catarrhalis, Basim I. Asmar
269. Tuberculosis (Mycobacteria tuberculosis), Jeffrey R. Starke
270. Nontuberculous Mycobacterial Infections, Jeffrey R. Starke
271. Leprosy, Wayne M. Meyers, Françoise Portaels, and Douglas S. Walsh
272. Buruli Ulcer (Mycobacterium ulcerans Infection), Wayne M. Meyers, Françoise Portaels, and Douglas S. Walsh
273. Mycoplasma Infections, Julia A. McMillan
274. Meisseria gonorrhoeae, Mary Allen Staat
275. Neisseria Meningitidis, Michele Estabrook
276. Nocardiosis, Mahed Abdel-Haq and Ashir Kumar
277. Pasteurella multocida, Morven S. Edwards
278. Pertussis, Beverly L. Connelly
279. Plague, Gary D. Overturf
280. Pneumococcal Infections, Sandra R. Arnold and P. Joan Chesney
281. Rat-Bite Fever, Lorry G. Rubin
282. Relapsing Fever, Dennis L. Murray
283. Salmonella, Shigella, and Escherichia coli, Andrew T. Pavia
284. Staphylococcus Infections, Beverly L. Connelly
285. Streptococcal Group A Infections, Mark R. Schleiss and Edward L. Kaplan
286. Group B Streptococcal Infections, Morven S. Edwards
287. Nongroup A or B Streptococci, Dwight A. Powell
288. Syphillis, Mary Allen Staat
289. Tetanus, Gary D. Overturf
290. Q Fever, Gordon E. Schutze
291. Tularemia, Jessica Nichols, Stephanie H. Stovall,and Richard F. Jacobs
292. Ureaplasma urealyticum Infections, Tara M. Randis and Adam J. Ratner
293. Yersinia enterocolitica Infections, Basim I. Asmir
294. Rickettsial Infections, Gordon E. Schutze
Part 6: Fungal Infections
295. Aspergillosis, Deborah Lehman
296. Blastomycosis, Dwight A. Powell
297. Candida, Katherine M. Knapp
298. Coccidioidomycosis, Mark R. Schleiss
299. Cryptococcosis, Deborah Lehman
300. Histoplasmosis, Martin B. Kleiman
301. Malassezia furfur, Dwight A. Powell
302. Microsporidiosis, Luis F. Barroso II and Richard L. Guerrant
303. Sporotrichosis, Donna M. Nobile and Martin B. Kleiman
304. Zygomycosis (Mucormycosis), Rebecca C. Brady
Part 7: Viral Infections
305. Arboviruses, Jason Brophy and Elizabeth Lee Ford-Jones
306. Enterovirus Infections, José R. Romero
307. Hemorrhagic Fevers, Eileen C. Farnon, Thomas G. Ksiazek, and Ali S. Khan
308. Viral Hepatitis, Henry Pollack and William Borkowsky
309. Herpes Simplex Virus Infections, David K. Hong and Charles G. Prober
310. Cytomegalovirus, Mark R. Schleiss
311. Epstein-Barr Virus (EBV) Mononucleosis, W. Garrett Hunt and Michael T. Brady
312. Human Herpesviruses 6 and 7, Mark R. Schleiss
313. Human Herpesvirus 8, Mark R. Schleiss
314. Varicella-Zoster Virus Infections, Sophie Hambleton
315. Human Immunodeficiency VirusType 1 Infection, Michael T. Brady
316. Measles, William J. Moss and Samuel L. Katz
317. Molluscum Contagiosum, Magdalene A. Dohil and Lawrence F. Eichenfield
318. Mumps, Dennis L. Murray
319. Human Parvovirus, Peggy Sue Weintrub
320. Rubella, Maria Jevitz Patterson
321. Rabies, Peggy Sue Weintrub
322. Smallpox, Anne A. Gershon
Part 8: Parasitic Infections--Nematodes
323. Antiparasitic Therapy, Melissa Hold and Michael Cappello
324. Ascariasis, John S. Schieffelin and Richard A. Oberhelman
325. Baylisascariasis, John S. Schieffelin and Richard A. Oberhelman
326. Dracunculiasis, John S. Schieffelin and Richard A. Oberhelman
327. Enterobiasis (Pinworm), Richard A. Oberhelman
328. Lymphatic Filariasis and Onchocerciasis, Doran L. Fink and Thomas B. Nutman
329. Hookworm, Melissa Held and Michael Cappello
330. Strongyloidiasis, Richard A. Oberhelman
331. Toxocariasis (Visceral and Ocular Larva Migrans), Richard A. Oberhelman and Peter J. Hotez
332. Trichinosis, Richard A. Oberhelman
333. Trichuriasis, John S. Schieffelin and Richard A. Oberhelman
334. Anasakiasis and Angiostrongyliasis, Richard A. Oberhelman
Part 9: Parasitic Infections--Trematodes
335. Foodborne Trematodiasis and Schistosomiasis, Jennifer Keiser and Jürg Utzinger
336. Diphyllobothriasis, Hector H. Garcia and Robert H. Gillman
337. Dipylidiasis, Hector H. Garcia and Robert H. Gilman
338. Echinococcosis, Hector H. Garcia, Saul Santivanez, and Robert H. Gilman
339. Hymenolepiasis, Hector H. Garcia and Robert H. Gilman
340. Taeniasis and Cysticercosis, Gary D. Overturf
Part 10: Parasitic Infections--Protozoa
341. Amebiasis, Ibne Karim M. Ali and William A. Petri, Jr.
342. Babesiosis, Peter J. Krause
343. Balantidiasis, Eduardo Ortega-Barria and Elidia Dominguez
344. Blastocytis hominis
345. Cryptosporidiosis, Luis F. Barroso, II, and Richard L. Guerrant
346. Cyclosporiasis, Cirle Alcantara Warren and Richard L. Guerrant
347. Dientamoebiasis, Dennis L. Murray
348. Free-Living Amebic Infections, Ibne Karim M. Ali and William A. Petri, Jr.
349. Giardiasis, Richard A. Oberhalman
350. Isosporiasis, Cirle Alcantara Warren
351. Leishmaniasis, Eduardo Ortega-Barria and Luz I. Romero
352. Malaria, Chandy C. John
353. Pneumocystis Pneumonia, Walter T. Hughes
354. Toxoplasmosis, Nicole M. A. Le Saux
355. Trypanosomiases, Eduardo Ortega-Barria
SECTION 18: DISORDERS OF THE SKIN
Section Editors: Beth Drolet and Sheila S. Galbraith
356. Functional Overview, Brook E. Tlougan and Amy S. Paller
357. Neonatal Dermatology, Sheila S. Galbraith
358. Disorders of the Epidermis, Kristen E. Holland
359. Disorders of the Dermis and Subcutaneous Tissue, Anita N. Haggstrom
360. Genetics Disorders of the Skin, Brook E. Tlougan and Amy S. Paller
361. Melanocytic Lesions andDisorders of Pigmentation, Julie V. Schaffer and Seth J. Orlov
362. Immunologic Diseases, Julie Prendiville
363. Neoplastic and Proliferative Disorders, Victoria R. Barrio and Lawrence F. Eichenfield
364. Vascular Tumors and Malformations, Ilona J. Frieden and Sheilagh M. Maguiness
365. Acne and Other Disorders of thePilosebaceous Unit, Sara W. Dill and Bari B. Cunningham
366. Disorders of Nails, Liborka Kos
367. Skin Infections and Exanthems, Jane S. Bellet and Anthony J. Mancini
368. Infestations, Denise W. Metry
SECTION 19: DISORDERS OF THE EAR, NOSE, AND THROAT
Section Editor: Joseph Kerschner
369. The Ear, John H. Greinwald Jr., Margaret A. Kenna,and Blake C. Papsin
370. Nose and Sinus, Ellen S. Deutsch and Cecille G. Sulman
371. The Pharynx and Upper Airway, Marshall E. Smith
372. The Head, Face, and Neck, Craig S. Derkay and Michael J. Cunningham
373. Head and Neck Masses, David E. Tunkel and Jonathan A. Perkins
SECTION 20: DISORDERS OF THE ORAL CAVITY
Section Editors: Howard L. Needleman and Stephen Shusterman
374. Dental Caries, Man Wai Ng and Isabelle I. Chase
375. Dental Emergency Care, Howard L. Needleman and Brian Grove
376. Dental Occlusion and Its Management, Richard Bruun and Sivabalan Vasudavan
377. Periodontal and Gingival Health and Diseases, Nadeem Y. Karimbux and David M. Kim
Preface
Acknowledgments
SECTION 1: FUNDAMENTALS OF PEDIATRICS
Section Editor: Thomas G. DeWitt
1. Role of the Pediatrician, Thomas G. DeWitt and Neal Halfon
2. Decision-Making: Use of Evidence-Based Medicine, Suresh Nagappan and Kenneth B. Roberts
3. Communication, Elizabeth A. Rider
4. Interviewing Techniques, Christopher F. Bolling
5. Systems of Practice and Office Management, Peter Margolis
6. Core Competencies, Theodore C. Sectish
7. Patient and Family-Centered Care, Jeffrey M. Simmons, Stephen E. Muething, and Kathleen L. Dressman
8. Disaster Preparedness, Janet M. Berreman and Linda Rudolph
9. Law, Ethics, and Clinical Judgment, Angela Roddey Holder
SECTION 2: HEALTH PROMOTION AND DISEASE PREVENTION
Section Editor: Eve R. Colson
Part 1: Health Maintenance Issues
10. Well-Child Care, Judith S. Shaw and Judith S. Palfrey
11. Child Development, Ilgi Ozturk Ertem and Carol Cohen Weitzman
12. Screening, Ada M. Fenick
13. Oral Heatlh Supervision, Ada M. Fenick and Linda P. Nelson
14. Complementary and Alternative Medicine (CAM), Anju Sawni
15. Culture and Pediatric Practice, Sakena Abedin
16. Gay and Lesbian Parents, Cindy M. Schorzman and Melanie A. Gold
17. Environmental Pediatrics, Ruth A. Etzel
18. Travel Medicine, Joseph A. Zenel and Chandy C. John
Part 2: Managing Family Transition
19. Family Function and Birth of a Child, William I. Cohen
20. Foster Care and Adoption, Brad D. Berman and Carol Cohen Weitzman
21. Family Discord and Divorce, Michael Jellinek
22. Supporting the Grieving Child and Family, David J. Schonfeld
SECTION 3: NUTRITION
Section Editor: Praveen S. Goday
23. Normal Nutritional Requirements, Praveen S. Goday
24. Breast-Feeding, Jane Morton and Ruth A. Lawrence
25. Infant Formula and Complementary Foods, Margaret Kirby
26. Postdischarge Nutritional Management of the Premature Infant, Utpala G. Das
27. Nutritional Issues: Toddler to Adolescent, Margaret Kirby and Praveen S. Goday
28. Assessment of Nutritional Adequacy, Praveen S. Goday
29. Malnutrition and Refeeding, Praveen S. Goday
30. Poor Weight Gain, Karen A. Francolla and Praveen S. Goday
31. Approach to the Infant and Child with Feeding Difficulty, Richard J. Noel
32. The Overweight or Obese Child, Michelle Smith-Beckley and Brian M. Fidlin
33. Specialized Nutrition Support, Praveen S. Goday
34. Nutritional Access Devices, Lillian Sablan and Karen Sherry
SECTION 4: ABUSE, NEGLECT, VIOLENCE
Section Editor: John M. Leventhal
35. Child Maltreatment: Neglect to Abuse, John M. Leventhal and Andrea G. Asnes
36. Family and Community Violence, Renée Boynton-Jarrett and Robert Sege
37. Child Abuse Prevention: What Pediatricians Can Do, Wendy Gwirtzman and Howard Dubowitz
SECTION 5: NEWBORN
Section Editors: Alan H. Jobe and James M. Greenberg
Part 1: Care of the Newborn
38. Historical Perspectives, James G. Greenberg
39. Care of the Fetus, Alan H. Jobe
40. Fetal Disorders, Timothy M. Crombleholme and Foong-Yen Lim
41. Neonatal Mortality and Morbidity, Avroy A. Fanaroff
42. Delivery Room Resuscitation, Myra H. Wyckoff
43. Transitional Changes in the Newborn, David P. Carlton
44. Examination of the Newborn Infant, Joseph A. Zeneel
45. Postnatal Care and Observation, Anthony E. Burgos
Part 2: Infants at Risk
46. Multiple Births, James M. Greenberg
47. The Small-for-Gestational Age Infant, William W. Hay, Jr.
48. Infant of a Diabetic Mother, Heather Morein French and Rebecca A. Simmons
Part 3: Specific Neonatal Conditions
49. Approach to the Cyanotic Infant, Robin H. Steinhorn
50. Abnormalities of the Lungs, M. Grisel Galarza and Ilene R.S. Sosenko
51. Metabolic Abnormalities, William W. Hay, Jr.
52. Brain Abnormalities and Injuries, Seetha Shankaran and C. Michael Cotton
53. Hematologic Abnormalities and Jaundice, Henry C. Lee and Ashima Madan
Part 4: Disorders Specifically Related to Preterm Birth
54. Respiratory Distress Syndrome, Thomas N. Hansen and Samuel Hawgood
55. Patent Ductus Arteriosus and Ductus Venosus, Ronald I. Clyman
56. Hemodynamics, Nick Evans
57. Necrotizing Enterocolitis, Barbara Warner
58. Intraventricular Hemorrhage, Henrietta S. Bada
59. Bronchopulmonary Dysplasia, Alan H. Jobe
60. Emergencies, James M. Greenberg
61. Special Intensive Care, Thomas A. Parker
62. Outcomes of Preterm and Term Infants, Marilee C. Allen
SECTION 6: PRINCIPLES OF ADOLESCENT CARE
Section Editors: Charles E. Irwin, Jr., Mary-Ann Shafer, and Anna-Barbara Moscicki
Part 1: Growth and Development
63. Somatic Growth and Development, Charles E. Irwin, Jr.
64. Reproductive Growth and Development in the Female Adolescent, Melissa Slivka, Anna-Barbara Moscicki, and Mary-Ann Shafer
65. Reproductive Growth and Development in the Male Adolescent, David J. Breland and Mark L. Rubinstein
66. Psychological Development, Elizabeth M. Ozer and Charles E. Irwin, Jr.
67. The Adolescent Visit, Charles E. Irwin, Jr.
Part 2: Health Problems of Adolescents
68. Mortality, Elizabeth M. Ozer
69. Morbidity, Charles E. Irwin, Jr.
70. Sexual Behavior, Erica B. Monasterio
71. Substance Use and Abuse, Stephanie N. Crewe and Arik V. Marcell
Part 3: Mental Health Disorders in the Adolescent
72. Depression, Anxiety, and Other Disorders, Kim Peter Norman
73. Disorders of Eating, Kim Peter Norman, Sara M. Buckelew, and Andrea K. Garber
Part 4: Reproductive Health Problems
74. Breast Masses, Jennifer C. Edman and Mary-Ann Shafer
75. Scrotal Masses, David J. Breland and Mark L. Rubinstein
76. Menstrual Problems, Jennifer C. Edman and Mary-Ann Shafer
77. Intrauterine and Ectopic Pregnancy, Erica B. Monasterio and Mary-Ann Shafer
78. Contraception, Erica B. Monasterio and Mary-Ann Shafer
SECTION 7: DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS
Section Editor: Martin T. Stein
Part 1: General Concepts
79. Introduction to Developmental and Behavioral Pediatrics, Martin T. Stein
80. Fundamental Concepts of Child Development, W. Thomas Boyce and Jack P. Shonkoff
81. Brain Development and Behavior, Charles A. Nelson III
82. Standardized Developmental Screening and Assessment Instruments, Martin T. Stein
Part 2: Developmental Variation to Disorder
83. Crying in Infants, Ronald G. Barr and Takeo Fujiwara
84. Hyperactivity and Inattention, Martin T. Stein and Michael I. Reiff
85. Learning Problems, Michael I. Reiff and Martin T. Stein
86. Language Delay, James S. Andrews and Heidi M. Feldman
87. Difficult Behavior, Martin T. Stein
88. Anxiety, Denise A. Chavira
89. Repetitive Behaviors, Adrian D. Sandler
90. Gender Identity and Sexual Behavior, Kenneth J. Zucker
91. Developmental Delay, Nathan J. Blum
Part 3: Major Psychopathologic Disorders
92. Autistic Spectrum Disorders, Michael I. Reiff
93. Affective Disorders and Suicide, Laura Prager, Steven C. Schlozman,and Michael Jellinek
94. Pediatric Condition Falsification, Herbert Schreier
95. Childhood Schizophrenia, Fred R. Volkmar
Part 4: Psychosocial Context of Development and Behavior
96. Families in the 21st Century:An Introduction to Families, Laurie J. Baumann and Ruth E. K. Stein
97. Nonparental Childcare, Nerissa S. Bauer
98. Vulnerable Child Syndrome, Yi Hui Liu
99. Adaptation to Illness, David J. Schonfeld
100. Poverty, Homelessness, andSocial Disorganization, Barry S. Zuckerman and Megan Sandel
101. Resiliency in Children and Adolescents, Saul Levine
SECTION 8: THE ACUTELY ILL INFANT AND CHILD
Section Editors: Julio Pérez Fontán and George Lister
Part 1: Assessment of the Acutely Ill Infant and Child
102. Respiratory Distress and Failure, Julio Pérez Fontán
103. Decreased Perfusion and Circulatory Shock, George E. Lister
104. Acute Neurological Dysfunction, Susan T. Arnold
105. The Febrile Child, M. Douglas Baker and Jeffrey R. Avner
Part 2: Stabilization and Management of the Acutely Ill Infant and Child
106. Monitoring of Vital Function, George E. Lister
107. Vascular Access, Andreas A. Theodorou and Robert A. Berg
108. Cardiopulmonary Resuscitation, Mary Fran Hazinski
109. Life Support Systems, Julio Pérez Fontán
110. Stabilization and Transport, Deborah Lerner, George Lister, and Julio Pérez Fontán
111. Management of Cerebral Edema andElevated Intracranial Pressure, Steven G. Kernie
112. Perioperative Care, Desmond B. Henry
113. Pain Management and Sedation, Alan Farrow-Gillespie
114. Acute Metabolic Dysfunction, Ralph J. DeBerardinis
Part 3: Injuries and Untoward Events
115. Acute Inflammation, Clifford W. Bogue
116. Trauma, Burns, and Bites, Robert P. Foglia
117. Submersion Injury, Pamela J. Okada and M. Douglas Baker
118. Foreign-Body Aspiration, Margaret A. Kenna
119. Apparent Life-Threatening Events and SIDS, Michael J. Corwin
120. Toxic Ingestions and Exposures, Sing-Yi Feng, Collin S. Goto, and M. Douglas Baker
121. Heat Stress, Michael Apkon
122. Poisonous Bites and Stings, Dee Hodge III and Carl R. Baum
SECTION 9: THE CHRONICALLY ILL INFANT AND CHILD
Section Editors: Julio Pérez Fontán and George E. Lister
Part 1: The Changing Outlook of Chronic Illness in Childhood
123. Psychological and Behavioral Responses in Children and Their Families, Patricia J. Hicks
124. The Technology-Dependent Child, John B. Gordon, Sarah P. Brown, Jerie Beth Karkos, and Lynn A. D'Andrea
Part 2: Death and Dying in Childhood
125. Caring for Children Dying From Chronic Disease, Arthur R. Ablin
126. Hospice and Palliative Care, Julie Hauer, Barbara L. Jones, and Joanne Wolfe
127. Law, Ethics, and Caring Near the End of Life, Angela Roddey Holder
SECTION 10: TRANSPLANTATION
Section Editor: Patrick J. Healey
128. Pediatric Transplantation, Patrick J. Healey
129. Kidney Transplantation, Jodi M. Smith and Ruth A. McDonald
130. Liver Transplantation, Patrick J. Healey
131. Intestinal and Multivisceral Transplant, Simon Horslen
132. Heart Transplant, Beth D. Kaufman
133. Hematopoietic Cell Transplantation, Ann E. Woolfrey, Paul A. Carpenter, and Jean E. Sanders
SECTION 11: INHERITED DISORDERS OF METABOLISM
Section Editor: Jean-Marie Saudubray
Part 1: Inborn Errors of Metabolism
134. Principles of Inborn Errors of Metabolism, Jean-Marie Saudubray and Joe T.R. Clarke
Part 2: Disorders of Amino Acid (AA) and Organic Acid (OA) Metabolism
135. Hyperphenylalaninemias, Bernd Christian Schwahn
136. Disorders of the Tyrosine Metabolism, Bernd Christian Schwahn
137. Disorders of the Branched Chain Amino and Organic Acid Metabolism, Stephen I. Goodman and Jean-Marie Saudubray
138. Disorders of Sulfur-Containing Amino Acid Meteabolism, Bernd Christian Schwahn
139. Disorders of Glycine, Serine, and Proline Metabolism, Bernd Christian Schwahn
140. Disorders of Metabolism of Lysine, Hydrozylysine, and Related Compounds, Stephen I. Goodman
141. Disorders of Metabolism of Neurotransmitter Amino Acids, Jaak Jaeken
142. Disorders of Creatine and Ornithine Metabolism, Sylvia Stockler-Ipsiroglu
143. Disorders of Amino Acid Transport Across Cell Membranes, Kirsti Näntö-Salonen and Ollie Simell
144. Other Disorders of Amino Acid Metabolism, Jean-Marie Saudubray
145. Urea Cycle and Related Disorders, Mendel Tuchman, Uta Lichter-Konecki, and Mark L. Batshaw
Part 3: Inborn Errors of Water Soluble Vitamins
146. Introduction, Stephen I. Goodman
147. Vitamin B12 and Folic Acid, David Watkins and David S. Rosenblatt
148. Biotin Responsive Disorders, Stephen I. Goodman
149. Vitamin B6 and Vitamin B1 Responsive Disorders, Jean-Marie Saudubray
Part 4: Disorders of Fatty Acid Oxidation, Ketogenesis, and Ketolysis
150. Disorders of Fatty Acid Oxidation, Stephen I. Goodman
151. Disorders of Ketogenesis, Stephen I. Goodman
152. Disorders of Ketolysis, Stephen I. Goodman
153. Disorders of Leukotriene Synthesis andFatty Aldehyde Dehydrogenase, Stephen I. Goodman
Part 5: Carbohydrate Metabolism
154. Disorders of Glycogen Metabolism, Priya S. Kishnani and Yuan-Tsong Chen
155. Disorders of Galactose and FructoseMetabolism and Gluconeogenesis, Priya S. Kishnani and Yuan-Tsong Chen
156. Disorders of Pentose Phosphate Pathway, Priya S. Kishnani and Yuan-Tsong Chen
157. Disorders of Glucose Transporters, René Santer
Part 6: Disorders of Oxidative Phosphorylation and Pyruvate Oxidation
158. Respiratory Chain Disorders, Salvatore DiMauro
159. Disorders of Energy Metabolism, Juan M. Pascual and Salvatore DiMauro
Part 7: Organelle Related Disorders
160. Mucopolysaccharidosis, Glycoproteinosis,and Mucolipidosis, James Edmond Wraith
161. Sphingolipidoses, Joe T.R. Clarke
162. Peroxisomal Disorders, David Valle, Gerald V. Raymond, and Stephen J. Gould
163. Congenital Disorders of Glycosylation, Jaak Jaeken
Part 8: Disorders of Lipid and Bile Acid Metabolism
164. Disorders of Cholesterol Synthesis, Peter T. Clayton
165. Disorders of Bile Acid Synthesis, Peter T. Clayton
166. Disorders of Lipid and Lipoprotein Metabolism, Peter O. Kwiterovich, Jr.
Part 9: Disorders of Nucleic Acids, Heme Metabolism, and Metals Transport
167. Disorders of Heme Biosynthesis: The Porphyrias, Robert J. Desnick
168. Disorders of Purine and Pyrimidine Metabolism, Georges van den Berghe
169. Disorders of Metal Metabolism, Jean-Marie Saudubray
SECTION 12: CLINICAL GENETICS AND DYSMORPHOLOGY
Section Editors: John C. Carey and Michael J. Bamshad
Part 1: The Genetic Approach to Disorders of Children
170. Key Principles in Human Genetics, Michael J. Bamshad and Lynn B. Jorde
171. Multifactorial Inheritance, Lynn B. Jorde
172. Principles of Care, Claire O. Leonard
Part 2: Chromosomal Disorders
173. Human Cytogenetics, Sarah T. South and John C. Carey
174. Chromosome Disorders, John C. Carey
Part 3: Birth Defects, Malformations, and Syndromes
175. Birth Defects, Malformations, and Syndromes, John C. Carey and Michael J. Bamshad
176. Syndromes of Multiple CongenitalAnomalies/Dysplasias, John C. Carey
177. Craniofacial Disorders, Carrie Lyn Heike and Michael L. Cunningham
178. Approach to the Child with Birth Defects, John C. Carey and Michael J. Bamshad
179. Genetics Skeletal Disorders, John C. Carey and Michael J. Bamshad
180. Congenital Contractures, Michael J. Bamshad and John C. Carey
181. Connective Tissue Dysplasias, Alan Rope
182. Neurocutaneous Disorders, David H. Viskochil
183. Environmental Causes of Birth Defects, Elizabeth Balken, Marsha Leen-Mitchell, Lynn P. Martinez, and Julia A. Robertson
184. Disorders of Accelerated Aging, John C. Carey
185. Genetic Evaluation of Developmental Delay/Mental Retardation, Agatino Battaglia and John C. Carey
SECTION 13: IMMUNOLOGIC DISORDERS
Section Editor: Talal A. Chatila
186. Overview of the Immune System, Eli M. Eisenstein, Kathleen E. Sullivan, and Calvin B. Williams
187. Undue Susceptibility to Infection, Talal A. Chatila
188. Primary Immunodeficiencies, Talal A. Chatila
189. Complement Disorders, Patricia C. Giclas and Ashley A. Frazer-Abel
SECTION 14: ALLERGIC DISORDERS
190. Allergic Disease and Atopy, Talal A. Chatila
191. Clinical Aspects of Allergic Diseases, Maria Garcia-Lloret
192. Allergic Rhinitis and Conjunctivitis, Maria Garcia-Lloret
193. Anaphylaxis, Urticaria, and Angioedema, Marc A. Riedel
194. Food Allergy, Maria Garcia-Lloret
195. Insect Allergy, Maria Garcia-Lloret
196. Latex Allergy, Marc A. Riedel
197. Adverse Reactions to Drugs, Marc A. Riedel
SECTION 15: RHEUMATOLOGY
Section Editor: Robert P. Sundel
Part 1: General Principles in Rheumatology
198. Pathogenesis of Inflammatory and Autoimmune Disorders, Kathleen E. Sullivan
199. History and Physical Exam, Robert P. Sundel
200. Diagnostic Testing in Rheumatology, Peter A. Nigrovic
Part 2: Specific Rheumatologic Disorders
201. Juvenile Idiopathic Arthritis, Carol A. Wallace, David A. Cabral, and Robert P. Sundel
202. Spondyloarthropathies, David A. Cabral and Lori B. Tucker
203. Vasculitides, Karyl S. Barron
204. Systemic Lupus Erythematosus, Overlap Connective Tissue Diseases, and Mixed Connective Tissue Disease, Earl D. Silverman
205. Juvenile Dermatomyositis, Lisa G. Rider
206. Scleroderma, Francesco Zulian
Part 3: Systemic Syndromes in Rheumatology
207. Musculoskeletal Pain Syndromes, Yukiko Kimura
208. Chronic Fatigue Syndrome, David S. Leslie
209. Autoinflammatory Disorders, Peter J. Hashkes
SECTION 16: THE MUSCULOSKELETAL SYSTEM
Section Editor: John A. Herring
210. Growth and Development, John G. Birch
211. The Limping Child, Lawson A.B. Copley
212. Torsional and Angular Deformities, Karl E. Rathjen
213. Disorders of the Foot, Charles E. Johnston
214. Disorders of the Knee, John A. Herring
215. Developmental Dysplasia of the Hip, David A. Podeszwa
216. Disorders of the Neck and Spine, Daniel J. Sucato
217. Disorders of the Upper Extremity, Marybeth Ezaki
218. Injuries, Philip Wilson
219. Tumors, B. Stephens Richards
220. Neuromuscular Disorders, Lori A. Karol
221. Common Orthopedia Misses, John A. Herring
SECTION 17: INFECTIOUS DISEASES
Section Editors: Anne A. Gershon and Peter J. Hotez
Part 1: Principles of Infectious Disease
222. Bacterial Pathogenesis, Janet R. Gilsdorf and Carl F. Marrs
223. Bacteremia, Sepsis, and Septic Shock, Stephanie H. Stovall and Richard F. Jacobs
224. Viral Pathogenesis, Anne Moscona and Anne A. Gershon
225. Infection Control, Margaret C. Fisher
226. Diagnostic Approaches for Infectious Diseases, John C. Christenson and E. Kent Korgenski
227. Acute Fever without a Focus, Steven Black
228. Fever of Unknown Origin, Russell W. Steele
229. Fever and Infection in theImmunocompromised Patient, David B. Haslam and Jeffrey Scott McKinney
230. Therapy for Perinatal and Neonatal Infections, David W. Kimberlin, Debra L. Palazzi,and Richard J. Whitley
Part 2: Infections of Organ Systems
231. Bacterial Infections of the CentralNervous System, Thomas S. Murray and Robert S. Baltimore
232. Viral Infections of the Central Nervous System, John F. Modlin
233. Sexually Transmitted Infections, Loris Y. Hwang, Anna-Barbara Moscicki,and Mary-Ann Shafer
234. Bone, Joint, and Soft Tissue Infections, Robin B. Churchill and Blanca E. Gonzalez
235. Cardiac Infections, Janet A. Stockheim and Stanford T. Shulman
236. Gastrointestinal Infections, Matthew B. Laurens and Michael S. Donnenberg
237. Infections of the Liver, M. Kyle Jensen and Grzegorz Telega
238. Urinary Tract Infections, Keith M. Krasinski
239. Catheter-Associated Infections, Marc Foca
Part 3: Infections of the Respiratory System
240. Community-Acquired and BacterialPneumonia in Children, Stephen I. Pelton
241. Viral Respiratory InfectionsIncluding Influenza, J. Robert Honegger and Michael T. Brady
242. Fungal Respiratory Infections, Hana Hakim and Aditya H. Gaur
243. Infections of the Ear, Jerome O. Klein
Part 4: Treatment and Prevention of Infectious Diseases
244. Immunizations, Kristina A. Bryant
245. Antiviral Therapy,David K. Hong and Charles G. Prober
246. Antibacterial Therapy, David K. Hong and Charles G. Prober
247. Antifungal Therapy, Patricia M. Flynn
Part 5: Bacterial Infections
248. Actinomycosis, Nahed Abdel-Haq and Ashir Kumar
249. Anaerobic Infections, Ayesha Mirza and Mobeen H. Rathore
250. Clostridial Infections, Jose Zayas and Mobeen H. Rathore
251. Anthrax (Bacillus anthracis), Denis Bratcher
252. Arcanobacterium, Dennis L. Murray
253. Bacillus cereus
254. Brucellosis, Ziad M. Shehab
255. Burkholderia and Pseudomonas, Jane L. Burns
256. campylobacter Infections, Guillermo M. Ruiz-Palacios
257. Cat Scratch Disease, Moshe Ephros and Michael Giladi
258. Chancroid (Hemophilus ducreyi), Mary Allen Staat
259. Chlamydia, Navjyot K. Vidwan and Mary Allen Staat
260. Cholera, Chokechai Rongkavilit and Ashir Kumar
261. Diphtheria, Gary D. Overturf
262. Enterococci, Dwight A. Powell
263. Haemophilus influenzae, Mark R. Schleiss and Arnold L. Smith
264. Legionella Pneumonia, Lorry G. Rubin
265. Leptospirosis, Anne A. Gershon and Michael Katz
266. Listeriosis, Ziad M. Shehab
267. Lyme Disease, Michael A. Gerber
268. Moraxella catarrhalis, Basim I. Asmar
269. Tuberculosis (Mycobacteria tuberculosis), Jeffrey R. Starke
270. Nontuberculous Mycobacterial Infections, Jeffrey R. Starke
271. Leprosy, Wayne M. Meyers, Françoise Portaels, and Douglas S. Walsh
272. Buruli Ulcer (Mycobacterium ulcerans Infection), Wayne M. Meyers, Françoise Portaels, and Douglas S. Walsh
273. Mycoplasma Infections, Julia A. McMillan
274. Meisseria gonorrhoeae, Mary Allen Staat
275. Neisseria Meningitidis, Michele Estabrook
276. Nocardiosis, Mahed Abdel-Haq and Ashir Kumar
277. Pasteurella multocida, Morven S. Edwards
278. Pertussis, Beverly L. Connelly
279. Plague, Gary D. Overturf
280. Pneumococcal Infections, Sandra R. Arnold and P. Joan Chesney
281. Rat-Bite Fever, Lorry G. Rubin
282. Relapsing Fever, Dennis L. Murray
283. Salmonella, Shigella, and Escherichia coli, Andrew T. Pavia
284. Staphylococcus Infections, Beverly L. Connelly
285. Streptococcal Group A Infections, Mark R. Schleiss and Edward L. Kaplan
286. Group B Streptococcal Infections, Morven S. Edwards
287. Nongroup A or B Streptococci, Dwight A. Powell
288. Syphillis, Mary Allen Staat
289. Tetanus, Gary D. Overturf
290. Q Fever, Gordon E. Schutze
291. Tularemia, Jessica Nichols, Stephanie H. Stovall,and Richard F. Jacobs
292. Ureaplasma urealyticum Infections, Tara M. Randis and Adam J. Ratner
293. Yersinia enterocolitica Infections, Basim I. Asmir
294. Rickettsial Infections, Gordon E. Schutze
Part 6: Fungal Infections
295. Aspergillosis, Deborah Lehman
296. Blastomycosis, Dwight A. Powell
297. Candida, Katherine M. Knapp
298. Coccidioidomycosis, Mark R. Schleiss
299. Cryptococcosis, Deborah Lehman
300. Histoplasmosis, Martin B. Kleiman
301. Malassezia furfur, Dwight A. Powell
302. Microsporidiosis, Luis F. Barroso II and Richard L. Guerrant
303. Sporotrichosis, Donna M. Nobile and Martin B. Kleiman
304. Zygomycosis (Mucormycosis), Rebecca C. Brady
Part 7: Viral Infections
305. Arboviruses, Jason Brophy and Elizabeth Lee Ford-Jones
306. Enterovirus Infections, José R. Romero
307. Hemorrhagic Fevers, Eileen C. Farnon, Thomas G. Ksiazek, and Ali S. Khan
308. Viral Hepatitis, Henry Pollack and William Borkowsky
309. Herpes Simplex Virus Infections, David K. Hong and Charles G. Prober
310. Cytomegalovirus, Mark R. Schleiss
311. Epstein-Barr Virus (EBV) Mononucleosis, W. Garrett Hunt and Michael T. Brady
312. Human Herpesviruses 6 and 7, Mark R. Schleiss
313. Human Herpesvirus 8, Mark R. Schleiss
314. Varicella-Zoster Virus Infections, Sophie Hambleton
315. Human Immunodeficiency VirusType 1 Infection, Michael T. Brady
316. Measles, William J. Moss and Samuel L. Katz
317. Molluscum Contagiosum, Magdalene A. Dohil and Lawrence F. Eichenfield
318. Mumps, Dennis L. Murray
319. Human Parvovirus, Peggy Sue Weintrub
320. Rubella, Maria Jevitz Patterson
321. Rabies, Peggy Sue Weintrub
322. Smallpox, Anne A. Gershon
Part 8: Parasitic Infections--Nematodes
323. Antiparasitic Therapy, Melissa Hold and Michael Cappello
324. Ascariasis, John S. Schieffelin and Richard A. Oberhelman
325. Baylisascariasis, John S. Schieffelin and Richard A. Oberhelman
326. Dracunculiasis, John S. Schieffelin and Richard A. Oberhelman
327. Enterobiasis (Pinworm), Richard A. Oberhelman
328. Lymphatic Filariasis and Onchocerciasis, Doran L. Fink and Thomas B. Nutman
329. Hookworm, Melissa Held and Michael Cappello
330. Strongyloidiasis, Richard A. Oberhelman
331. Toxocariasis (Visceral and Ocular Larva Migrans), Richard A. Oberhelman and Peter J. Hotez
332. Trichinosis, Richard A. Oberhelman
333. Trichuriasis, John S. Schieffelin and Richard A. Oberhelman
334. Anasakiasis and Angiostrongyliasis, Richard A. Oberhelman
Part 9: Parasitic Infections--Trematodes
335. Foodborne Trematodiasis and Schistosomiasis, Jennifer Keiser and Jürg Utzinger
336. Diphyllobothriasis, Hector H. Garcia and Robert H. Gillman
337. Dipylidiasis, Hector H. Garcia and Robert H. Gilman
338. Echinococcosis, Hector H. Garcia, Saul Santivanez, and Robert H. Gilman
339. Hymenolepiasis, Hector H. Garcia and Robert H. Gilman
340. Taeniasis and Cysticercosis, Gary D. Overturf
Part 10: Parasitic Infections--Protozoa
341. Amebiasis, Ibne Karim M. Ali and William A. Petri, Jr.
342. Babesiosis, Peter J. Krause
343. Balantidiasis, Eduardo Ortega-Barria and Elidia Dominguez
344. Blastocytis hominis
345. Cryptosporidiosis, Luis F. Barroso, II, and Richard L. Guerrant
346. Cyclosporiasis, Cirle Alcantara Warren and Richard L. Guerrant
347. Dientamoebiasis, Dennis L. Murray
348. Free-Living Amebic Infections, Ibne Karim M. Ali and William A. Petri, Jr.
349. Giardiasis, Richard A. Oberhalman
350. Isosporiasis, Cirle Alcantara Warren
351. Leishmaniasis, Eduardo Ortega-Barria and Luz I. Romero
352. Malaria, Chandy C. John
353. Pneumocystis Pneumonia, Walter T. Hughes
354. Toxoplasmosis, Nicole M. A. Le Saux
355. Trypanosomiases, Eduardo Ortega-Barria
SECTION 18: DISORDERS OF THE SKIN
Section Editors: Beth Drolet and Sheila S. Galbraith
356. Functional Overview, Brook E. Tlougan and Amy S. Paller
357. Neonatal Dermatology, Sheila S. Galbraith
358. Disorders of the Epidermis, Kristen E. Holland
359. Disorders of the Dermis and Subcutaneous Tissue, Anita N. Haggstrom
360. Genetics Disorders of the Skin, Brook E. Tlougan and Amy S. Paller
361. Melanocytic Lesions andDisorders of Pigmentation, Julie V. Schaffer and Seth J. Orlov
362. Immunologic Diseases, Julie Prendiville
363. Neoplastic and Proliferative Disorders, Victoria R. Barrio and Lawrence F. Eichenfield
364. Vascular Tumors and Malformations, Ilona J. Frieden and Sheilagh M. Maguiness
365. Acne and Other Disorders of thePilosebaceous Unit, Sara W. Dill and Bari B. Cunningham
366. Disorders of Nails, Liborka Kos
367. Skin Infections and Exanthems, Jane S. Bellet and Anthony J. Mancini
368. Infestations, Denise W. Metry
SECTION 19: DISORDERS OF THE EAR, NOSE, AND THROAT
Section Editor: Joseph Kerschner
369. The Ear, John H. Greinwald Jr., Margaret A. Kenna,and Blake C. Papsin
370. Nose and Sinus, Ellen S. Deutsch and Cecille G. Sulman
371. The Pharynx and Upper Airway, Marshall E. Smith
372. The Head, Face, and Neck, Craig S. Derkay and Michael J. Cunningham
373. Head and Neck Masses, David E. Tunkel and Jonathan A. Perkins
SECTION 20: DISORDERS OF THE ORAL CAVITY
Section Editors: Howard L. Needleman and Stephen Shusterman
374. Dental Caries, Man Wai Ng and Isabelle I. Chase
375. Dental Emergency Care, Howard L. Needleman and Brian Grove
376. Dental Occlusion and Its Management, Richard Bruun and Sivabalan Vasudavan
377. Periodontal and Gingival Health and Diseases, Nadeem Y. Karimbux and David M. Kim
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