Cardiovascular Effects of Inhaled Ultrafine and Nano-Sized Particles

This book demystifies the complex issues that determine the impact of air pollution on the cardiovascular system. It covers a range of relevant topics including particulate matter (PM) sources and characterization, methods of exposure, impact of PM on cells and systems, the role of particles in the pathophysiology of cardiovascular disease, risk assessment, and potential environmental and therapeutic interventions. Case studies, the implications of health policy and regulations, and toxicological and epidemiological data are also included. This timely, in-depth information will benefit toxicologists, epidemiologists, public and environmental health professionals, experts in cardiovascular medicine, occupational and environmental health scientists, physicians, and regulatory professionals.

Flemming R. Cassee is head of the Department of Inhalation Toxicology, deputy head of the Center for Environmental Health, and leader of the program on air pollution and health at the National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands. Nicholas L. Mills is a British Heart Foundation Clinical Fellow at the University of Edinburgh and Specialist Registrar in Cardiology at the Royal Infirmary of Edinburgh. David E. Newby is the British Heart Foundation John Wheatley Chair of Cardiology at the University of Edinburgh. He is a Consultant Interventional Cardiologist at the Royal Infirmary of Edinburgh, Director of the Wellcome Trust Clinical Research Facility, Director of the Clinical Research Imaging Centre, and Director of Research and Development for NHS Lothian.