Giardia and Cryptosporidium

, by M. G. Ortega-Pierres; R. Caccio; S. Fayer; T. Mank; H. Smith

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ISBN: 9781845933913 | 1845933915
Cover: Hardcover
Copyright: 4/26/2009

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Giardia and Cryptosporidium are both parasites of considerable global interest due to the gastrointestinal problems they can cause in humans, as well as domestic and wild animals. Despite its long history as the causative agent of giardiasis, the clinical and zoonotic significance of Giardia infections in humans and animals is only beginning to emerge with the application of molecular tools. Less is known about Cryptosporidium and studies seek to understand the impact of its infection in livestock and other animals, its epidemiology and zoonotic significance.

Contributors	p. ix
The Impact of Giardia on Science and Society	p. 1
Cryptosporidium in Cattle: From Observing to Understanding	p. 12
Taxonomy, Nomenclature and Evolution
Names Do Matter	p. 25
Centenary of the Genus Cryptosporidium: From Morphological to Molecular Species Identification	p. 31
Molecular Epidemiology and Typing
Molecular Epidemiology of Human Cryptosporidiosis in Developing Countries	p. 51
Molecular Epidemiology and Typing of Non-human Isolates of Cryptosporidium	p. 65
Insights Into the Molecular Detection of Giardia duodenalis: Implications for Epidemiology	p. 81
Zoonotic, Human and Animal Health Issues
Wildlife with Giardia: Villain, or Victim and Vector?	p. 94
The Role of Livestock in the Foodborne Transmission of Giardia duodenalis and Cryptosporidium spp. to Humans	p. 107
The Risk of Zoonotic Genotypes of Cryptosporidium spp. in Watersheds	p. 123
Clinical and Molecular Epidemiology
Clinical Presentation in Cryptosporidium-infected Patients	p. 131
Molecular Epidemiology of Cryptosporidium and Giardia Infections	p. 138
Advances in Diagnosis
Advances in Diagnosis: is Microscopy Still the Benchmark?	p. 147
Treatment of Drinking Water
Control of Cryptosporidium and Giardia in Surface Water by Disinfection	p. 158
Towards Methods for Detecting UV-induced Damage in Individual Cryptosporidium parvum and Cryptosporidium hominis Oocysts by Immunofluorescence Microscopy	p. 179
Control in Water
Effect of Environmental and Conventional Water Treatment Processes on Waterborne Cryptosporidium Oocysts	p. 198
Methods for Genotyping and Subgenotyping Cryptosporidium spp. Oocysts Isolated During Water and Food Monitoring	p. 210
Intervention in Waterborne Disease	p. 227
Other Waterborne Protozoa
Occurrence and Control of Naegleria fowleri in Drinking Water Wells	p. 238
Environmental Factors Influencing the Survival of Cyclospora cayetanensis	p. 248
Basic Biology
Recent Advances in the Developmental Biology and Life Cycle of Cryptosporidium	p. 255
Basic Biology of Giardia lamblia: Further Studies on Median Body and Funis	p. 266
Giardia intestinalis: a Microaerophilic Parasite with Mitochondrial Ancestry	p. 284
Metabolomics and Transcriptome
Cytoskeleton-based Lipid Transport in a Parasitic Protozoan, Giardia lamblia	p. 292
Signalling During Giardia Differentiation	p. 309
Genomics
Preliminary Analysis of the Cryptosporidium muris Genome	p. 320
Proteomics
Proteomic Analyses in Giardia	p. 328
Proteomic and Genomic Approaches to Understanding the 'Power Plant' of Cryptosporidium	p. 344
Biochemistry and Physiology
Energy Metabolism and Carbon Flow in Crytosporidium parvum	p. 360
The Surface Protein Repertoires of Cryptosporidium spp. and Other Apicomplexans	p. 369
Giardan: Structure, Synthesis, Regulation and Inhibition	p. 382
Cell Biology and Signalling
Protein Kinase C in Giardia duodenalis: a Family Affair	p. 398
Secretory Granule Biogenesis and the Organization of Membrane Compartments via SNARE Proteins in Giardia lamblia	p. 409
Molecular Mechanisms of Cryptosporidium-induced Host Actin Cytoskeleton Dynamics	p. 418
Pathogenesis and Host-Parasite Relationship
Pathogenic Mechanisms in Giardiasis and Cryptosporidiosis	p. 428
Interferon-gamma (IFN-g) in Immunological Control of Cryptosporidial Infection	p. 442
Immune Response to Giardia Infection: Lessons from Animal Models	p. 451
Drug Treatment and Novel Drug Targets
Drug Treatment and Novel Drug Targets Against Giardia and Cryptosporidium	p. 463
Index	p. 483
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Giardia and Cryptosporidium

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