The Biological Basis of Cancer

This is a revised and updated edition of a text used in undergraduate courses on cancer biology. It covers everything from the molecular basis of cancer to clinical aspects of the subject, and has a lengthy bibliography designed to assist newcomers with the cancer literature. An introduction acquaints students with the biological principles of cancer and the human dimensions of the disease by considering genuine cases of cancer in fictionalized letters. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Also included are an appendix with descriptions of common forms of cancer, a glossary of cancer-related terms and colour plates to illustrate the pathology of many of the types of cancer discussed in the text. Upper-division undergraduates with a background in freshman biology and chemistry, as well as beginning graduate students will find this a valuable text.

Robert G. McKinnell is Professor Emeritus of Genetics, Cell Biology, and Development at the University of Minnesota Ralph E. Parchment is Chief Scientific Officer at Sci Tech Development in Detroit Alan O. Perantoni is a principal investigator and Chief of the Differentiation and Neoplasia Section in the Laboratory of Comparative Carcinogenesis, National Cancer Institute Ivan Damjanov is Professor of Pathology at the University of Kansas School of Medicine G. Barry Pierce is Centennial Distinguished Research Professor of Pathology Emeritus at the University of Colorado Health Sciences Center