Bioinspired Catalysis Metal-Sulfur Complexes

This book provides an overview of bioinspired metal-sulfur catalysis by covering structures, activities and model complexes of enzymes exhibiting metal sulphur moieties in their active center.

Wolfgang Weigand received his PhD degree from the Ludwig-Maximilian-University of Munich under the supervision of Professor W. Beck in 1986. After a postdoctoral stay with Professor D. Seebach at ETH Zurich, he finished his habilitation at Ludwig-Maximilian-University in 1994. Since 1997 he is Professor of Inorganic Chemistry at the Friedrich-Schiller-University Jena. He has received the "Forschungspreis der Thuringer Ministerin fur Wissenschaft, Forschung und Kunst" and he is also "Ordentliches Mitglied der Akademie gemeinnutziger Wissenschaften zu Erfurt".

Philippe Schollhammer, Professor of Chemistry, obtained his PhD in 1994 at UBO (Universite de Bretagne Occidentale, Brest-France) under the supervision of Professor F.Y. Petillon. In 2001, he joined during a sabbatical leave the group of Professor R.H. Henderson at the University of Newcastle upon Tyne, UK. His current research interests include activation of small molecules by organometallic dinuclear complexes.

PART I: PRIMORDIAL METAL-SULFUR MEDIATED REACTIONS
From Chemical Invariance to Genetic Variability
Fe-S Clusters: Biogenesis and Redox, Catalytic and Regulatory Properties

PART II: MODEL COMPLEXES OF THE ACTIVE SITE OF HYDROGENASES -
PROTON AND DIHYDROGEN ACTIVATION
[NiFe] Hydrogenases
[Fe-Fe]Hydrogenases Models: An Overview
The Third Hydrogenase
DFT Investigation of Models Related to the Active Site of Hydrogenases
Mechanistic Aspects of Biological Hydrogen Evolution and Uptake

PART III: NITROGEN FIXATION
Structures and Functions of the Active Site of Nitrogenases
Model Complexes of the Active Site of Nitrogenases: Recent Advances
A Unified Chemical Mechanism for Hydrogenation Reactions Catalysed by Nitrogenase
Binding Substrates to Synthetic Fe-S-Based Clusters and the Possible Relevance to Nitrogenases

PART IV: MISCELLANEOUS: RCN ACTIVATION, DMSO REDUCTION
Sulfur-Oxygenation and Functional Models of Nitrile Hydratase
Molybdenum and Tungsten Oxidoreductase Models

PART V: APPLICATIVE PERSPECITVES
Electrode Materials and Artificial Photosynthetic Systems