The ESC Textbook of Heart Failure

The ESC Textbook of Heart Failure is the latest addition to the European Society of Cardiology (ESC) publications portfolio and is fully supported by the European Heart Failure Association.
The textbook brings together internationally renowned experts in the field of heart failure to present an up-to-date understanding of all aspects of this chronic condition that worsens with time. It is estimated that the worldwide population of patients suffering from heart failure is approximately 26 million. This clinically oriented work reflects contemporary European guidelines from the ESC and the European Heart Failure Association and summarizes the latest evidence from clinical trials.
Made up of eighteen different sections the textbook covers the epidemiology, etiology, prevention, pathophysiology, and clinical phenotypes of heart failure. The assessment and management of chronic, acute, and advance heart failure are all discussed in detail. As well as chapters dedicated to self-care and patient education, the multidisciplinary approach to heart failure management, and clinical trial design and interpretation. The future direction of the field is discussed throughout with separate chapters on digital health, big data, and telemedicine/remote monitoring in heart failure also included.
A must read for cardiovascular healthcare specialists in Europe and across the world it should also appeal to those in training, general physicians and those caring of the elderly, cardiothoracic surgeons, primary care doctors, and specialist nurses too.

Section 1: Universal definition of heart failure
1.1. Universal definition of heart failure, Andrew JS Coats, Biykem Bozkurt and Petar M. Seferovic
Section 2: Epidemiology of heart failure
2.1. Epidemiology of heart failure, Amy Groenewegen, Ivan Milinkovi?, Arno W Hoes, Arend Mosterd, Frans H Rutten
Section 3: Etiology of heart failure
3.1. Coronary artery disease, (Rocco Antonio Montone, Maurizio Volterrani, Jian Zhang and Filippo Crea
3.2. Hypertension, Athanasios Manolis and Yuri Lopatin
3.3. Valvular heart disease, Ana Pardo Sanz, Ivan Milinkovic and Josep Zamorano
3.4.1. Genetic basis of cardiomyopathies, Thomas Thum, Stephane Heymans, and Johannes Backs
3.4.2. Dilated and hypokinetic non-dilated cardiomyopathy, Petar M.Seferovic, Biykem Bozkurt, and Marija Polovina
3.4.3. Hypertrophic cardiomyopathy, Perry Elliott, Michel Noutsias and Aris Anastasakis
3.4.4. Restrictive cardiomyopathy, Claudio Rapezzi, Alberto Aimo, Ales Linhart, and Andre Keren
3.4.5. Arrhythmogenic right ventricular cardiomyopathy, Cristina Basso, Hugh Calkins and Domenico Corrado
3.4.6. Peripartum cardiomyopathy, Karen Sliwa and Johann Bauersachs
3.4.7. Takotsubo cardiomyopathy, Jelena Templin-Ghadri, Michael Würdinger, Johann Bauersachs, and Christian Templin
3.5. Myocarditis and pericarditis, Stephane Heymans, Arsen Risti?, Yehuda Adler, and Massimo Imazio
3.6. Congenital heart disease, Werner Budts and Jolien Roos-Hesselink
3.7. Endocrine and metabolic disorders, Martin Huelsmann, Jelena Seferovic and Francesco Cosentino
3.8. Obesity, Lina Badimon, Stefan Anker and Stephan von Haehling
3.9. Cancer and cancer therapy, Alexander Lyon, Dimitrios Farmakis, Daniela Cardinale and Teresa Lopez Fernandez
3.10. Toxins (e.g. alcohol etc.) and infections, Antonello Gavazzi, Maria Nunes, and Fausto Pinto
Section 4: Prevention of heart failure
4.1. Prevention of heart failure, Massimo Piepoli, Maria Benedetta Matrone, Paul Dendale, and Shelley Zieroth
Section 5: Pathophysiology of heart failure
5.1. Molecular and cellular mechanisms, (Junjie Xiao, Thomas Thum, Gianluigi Condorelli and Johannes Backs
5.2. Alterations in myocardial metabolism, Edoardo Bertero and Chistoph Maack
5.3. Ventricular remodelling, Javier Diez Martinez and Hans-Peter Brunner La Rocca
5.4. Neurohormonal activation, Antoni Bayes Gennis and Faiez Zannad
5.5. Immune-mediated mechanisms, Urlich Hofmann, Stefan Frantz and Nikolaos Frangogiannis
5.6. Inflammation, oxidative stress and endothelial dysfunction, Stephane Heymans
5.7. Alterations in peripheral circulation and renal function, Alterations in peripheral circulation and renal function (
5.8. Systemic adaptations in metabolism and nutritive status, (Stephan von Haehling and Wolfram Doehner
Section 6: Clinical phenotypes of chronic heart failure
6.1. HFrEF, Thomas Luscher, Petar Seferovic, and Brian Halliday
6.2. HFmrEF, Adrian Voors, Brenda Moura, Lars Lund and Carolyn Lam
6.3. HFpEF, Rudolf De Boer, Burkert Pieske, and Barry Borlaug
6.4. Right heart failure, Thomas Luscher, Thomas M. Gorter, Susanna Price, Michael Gatzoulis and Anneline Te Riele
Section 7: Chronic heart failure: diagnostic and prognostic assessment
7.1. Clinical assessment, Michel Komajda, Piotr Ponikowski, and Evgeny Shlyakhto
7.2. Biomarkers in diagnostic and prognostic assessment, Rudolf de Boer, Antioni Bayes Genis and James Januzzi
7.3. Echocardiography, Philippe Debonnaire, Victoria Delgado, Thor Edvardsen, Bogdan Popescu, and Jeroen Bax
7.4. Nuclear medicine, Danilo Neglia and Alessia Gimelli
7.5. Cardiac computed tomography, Stephan Achenbach and Amina Rakisheva
7.6. Cardiac magnetic resonance, Anna Baritussio, Noor Sharrack, Sven Plein, and Chiara Bucciarelli-Bucci
7.7. Cardiopulmonary exercise, Luca Moderato, Davide Lazzeroni, Stamatis Adamopoulos, Alain Cohen-Solal and Massimo Piepoli
7.8. Cardiac catheterization, invasive imaging and haemodynamic assessment, Christian Hamm, Brigit Assmus and Veselin Mitrovic
Section 8: Chronic heart failure: pharmacological management
8.1. Angiotensin converting enzyme inhibitors, Roberto Ferrari, Gabriele Guardigli, and Biykem Bozkurt
8.2. Angiotensin I receptor blockers, Ileana L. Pina and Magdy Abdelhamid
8.3. ARNI, Petar M. Seferovic, Michele Senni, Marija Polovina and Andrew JS Coats
8.4. Beta-blockers, Daniela Tomasoni, Marianna Adamo, Hiroyuki Tsutsui, and Marco Metra
8.5. Mineralocorticoid receptor agonists, Bertram Pitt, João Pedro Ferreira and Faiez Zannad
8.6. Ivabradine, Michael Bohm and Michel Komajda
8.7. Vasodilators, Eftihia Polyzogopoulou, Maria Nikolaou, John Parissis and Alexandre Mebazaa
8.8. Digitalis glycosides, Udo Bavendiek and Johann Bauersachs
8.9. Diuretics, Jeroen Dauw, Stephen Gottlieb and Wifried Mullens
8.10. Inotropes and inodilators, Jan Biegus, Piotr Ponikowski, and Christoph Maack
8.11. SGLT2 inhibitors, Petar M. Seferovic, Francesco Cosentino, Giuseppe Rosano and James Januzzi
8.12. Ancillary pharmacological treatment options, Stefan Agewall, Isabelle van Gelder, and Irene Savelieva
8.13. New and emerging therapies, Giuseppe Rosano, Gerasimos Filippatos, and Randall Starling
Section 9: Chronic heart failure: non-pharmacological management
9.1. Implantable cardioverter defibrillator, Gianluigi Savarese, Cecilia Linde and Kenneth Dickstein
9.2. Cardiac resynchronization therapy, Pieter Martens, Eva Goncalvesova, and Wilfried Mullens
9.3. Cardiac surgery, Felix Schoenrat, Franz-Josef Neumann, Miguel Sousa Uva and Volkmar Falk
9.4. Valve interventions, Stefan Orwat, Stefan Anker and Helmut Baumgartner
9.5. Ancillary procedures, Andrew JS Coats, Piotr P Ponikowski, Maria-Rosa Costanzo and William T. Abraham
9.6. Cardiac rehabilitation, Maurizio Volterrani, Alain Cohen-Solal, Stamatis Adamopulos, Dimitris Miliopoulos, Ferdinando Iellamo, and Massimo Piepoli
Section 10: Acute heart failure
10.1. Acute heart failure: diagnostic and prognostic assessment, Ovidiu Chioncel, Gerasimos Filippatos, Alexandre Mebazaa, Veli-Pekka Harjola, and Josep Masip
10.2. Acute heart failure: management, Katerina Fountoulaki, John Parissis, Sean Collins, Mehmet Birhan Yilmaz, and Alexandre Mebazaa
Section 11: Advanced heart failure
11.1. Advanced heart failure: assessment, Tuvia Ben Gal, Mariell Jessup, and Maria-Rosa Costanzo
11.2. Advanced heart failure: management, Daniela Tomasoni, Marianna Adamo, and Marco Metra
11.3. Mechanical circulatory support, Mandeep Mehra and Finn Gustafsson
11.4. Heart transplantation, Davor Milicic, Mandeep Mehra, and Randall Starling
11.5. Palliative care and end-of-life management, Tiny Jaarsma, Donna Fitzsimons, Lisa Hjelmfors, Loreena Hill, Ekaterini Lambrinou, and Anna Strömberg
Section 12: Comorbidities and clinical conditions
12.1. Chronic kidney disease: Clinical Aspects of Chronic Kidney Disease in Heart Failure, Pieter Martens and Hans-Peter Brunner-La Rocca
12.2. Dyskalaemia, Javed Butler, Wilfried Mullens and Kevin Damman and João Pedro Ferreira
12.3. Chronic lung disease, Josep Masip, Karina Portillo and Mattia Arrigo
12.4. Ventilatory Abnormalities and Sleep Disordered Breathing, Piergiuseppe Agostoni, Elisabetta Salvioni, Maria Rosa Costanzo, and Andrew JS Coats
12.5. Pulmonary hypertension, Irene M. Lang and Stephan Rosenkranz
12.6. Cardiac rhythm disorders, Silvia Priori, Alessandro Trancuccio, Alessia Chiara Latini, Carlo Arnò, Deni Kukavica, and Andrea Mazzanti
12.7. Management of atrial fibrillation in heart failure, Paulus Kirchhof, Andreas Metzner, Ruben Schleberger and Douglas Packer
12.8. Diabetes, metabolic syndrome and endocrine disorders, Giuseppe Rosano, Javed Butler, Petar M. Seferovi?, Jelena Seferovic and Francesco Cosentino
12.9. Systemic immune medicated diseases, Giacomo De Luca, Luca Moroni, Alessandro Tomelleri, R Marcolongo, Lorenzo Dagna, Alida LP Caforio, and Marco Matucci-Cerinic
12.10. Liver and gut dysfunction, Yuri Lopatin and Gianluigi Savarese
12.11. Anaemia and iron deficiency, Ewa Jankowska, Piotr Ponikowski, and Stefan Anker
12.12. Depression and cognitive impairment, Wolfram Doehner, Cristiana Vitale, and Mehmet Birhan Yilmaz
12.13. Cancer, Alexander Lyon, Dimitrios Farmakis, Rudolf de Boer, and Yuri Belenkov
12.14. Pregnancy, Johann Bauersachs, Denise Hilfiker-Kleiner and Karen Sliwa
12.15. Frailty, Ewa Jankowska, Cristiana Vitale and Dong-Ju Choi
Section 13: Self-care and patient education
13.1. Self-care and patient education, Tiny Jaarsma, Loreena Hill, Ekaterini Lambrinou, Anna Stromberg, and Tina Hansen
Section 14: Multidisciplinary approach to heart failure management
14.1. Multidisciplinary approach to heart failure management, Loreena Hill, Friedrich Koehler, Tiny Jaarsma, Marija Polovina, Katherine McCreary, and Andrew JS Coats
Section 15: Clinical trial design and interpretation
15.1. Clinical trial design and interpretation, Gianluigi Savarese, Marija Polovina and Gerasimos Filippatos
Section 16: Digital health in heart failure
16.1. Digital health in heart failure, Arvind Singhal and Martin Cowie
Section 17: Big data in heart failure
17.1. Big data in heart failure, Mamas Mamas and Dipak Kotecha
Section 18: Telemedicine and remote monitoring
18.1. Telemedicine and remote monitoring, Tarek Bekfani, Friedrich Koehler and William T. Abraham