Age-Related Macular Degeneration Current Management

Retinal disease in general, and age-related macular degeneration (AMD) specifically, is of major interest worldwide due to the increasing aging population and the revolution in management of wet AMD over the past several years. Age-Related Macular Degeneration presents an up-to-date, clinically relevant monograph on the current diagnosis and management of AMD.

Age-Related Macular Degeneration by Drs. Jay S. Duker and Andre J. Witkin serves as a reference for ophthalmologists treating AMD in the clinic as well as other eye care professionals who see and counsel patients with AMD. Chapters will focus on the pathogenesis and risk factors for AMD, the diagnosis of AMD, treatment options, and promising investigative interventions. To help readers gain familiarity recognizing AMD, the book contains multiple images in different formats: high quality color fundus photographs, black-and-white angiograms, black-and-white autofluorence images, and both color and black-and-white OCT images.

Relevant to current management of AMD, Age-Related Macular Degeneration: Current Management concentrates on “clinical utility” rather than emphasizing published studies, filling the current void in the market for the general ophthalmology and optometry audience. Comprehensive ophthalmologists, optometrists and retinal specialists will appreciate the book’s practical approach to AMD.

Jay S. Duker, MD is professor and chair of the Department of Ophthalmology at Tufts Medical Center and Tufts University School of Medicine and the Director of the New England Eye Center in Boston. Dr. Duker received his medical degree magna cum laude from Jefferson Medical College in Philadelphia. He completed an internal medicine internship at the Beth Israel Hospital in Boston. Dr. Duker then completed an ophthalmology residency, serving as chief resident, followed by a retina and vitreous surgery fellowship, at the Wills Eye Hospital in Philadelphia.

Dr. Duker’s major research interests include imaging of the posterior segment, retinal vascular disease, and drug delivery to the posterior segment. He has pursued those interests as a coinvestigator or principal investigator of numerous studies funded by the National Institutes of Health/National Eye Institute, Massachusetts Institute of Technology, and industry, including studies of optical coherence tomography and several phase III trials. Specializing in medical and surgical diseases of the posterior segment, his surgical expertise includes macular diseases, retinal detachment, proliferative vitreoretinopathy, diabetic retinopathy, and intraocular tumors. He has published more than 180 journal articles, and he has been lead editor on 3 books and 13 book chapters. In addition, Dr. Duker lectures extensively both nationally and internationally. He is an associate editor of Ophthalmic Surgery and Laser Therapy and has served on the editorial boards of Review of Ophthalmology, Evidence-Based Eye Care, and Retina Today. He has been a reviewer for many journals, including Ophthalmology, American Journal of Ophthalmology, Archives of Ophthalmology, Ophthalmic Surgery and Lasers, Retina, and The New England Journal of Medicine, among others. Dr. Duker is the recipient of the Honor Award and Senior Honor Award from the American Academy of Ophthalmology.
 
Andre J. Witkin, MD was born in Waterville, Maine. He attended Dartmouth College, earning his bachelor’s degree magna cum laude with high honors in biology. He earned his MD from Weill Cornell Medical College in New York City and did his ophthalmology residency at the New England Eye Center of Tufts Medical Center in Boston. Dr. Witkin then did a 2-year fellowship in retinal disease and vitreoretinal surgery at the Wills Eye Institute in Philadelphia. In 2012, he joined the ophthalmology faculty at the New England Eye Center of Tufts Medical Center as an assistant professor. Dr. Witkin has a special interest in clinical research, particularly in the field of retinal imaging. He has published more than 30 articles in peer-reviewed journals and several book chapters and has presented at more than a dozen national meetings in the field of ophthalmology. Dr. Witkin is currently the primary investigator for a number of clinical trials in macular degeneration and central serous chorioretinopathy at the New England Eye Center.

Dedication 
About the Editors 
Contributing Authors 
Preface  

Chapter 1 Epidemiology, Genetics, and Modifiable Risk Factors 
Anita Agarwal, MD
Chapter 2 Pathology of Age-Related Macular Degeneration 
Nora M.V. Laver, MD
Chapter 3 Clinical Diagnosis, Classification, and Patient Counseling 
Sana Nadeem, MBBS and Nadia K. Waheed, MD, MPH
Chapter 4 Ancillary Testing in Age-Related Macular Degeneration 
Section 1: Fundus Photography and Autofluorescence 
S.K. Steven Houston III, MD and Sunir J. Garg, MD, FACS
Section 2: Optical Coherence Tomography 
Andre J. Witkin, MD
Section 3: Fluorescein Angiography and Indocyanine Green Angiography
Michael D. Tibbetts, MD and Elias Reichel, MD
Chapter 5 Mimickers of Age-Related Macular Degeneration 
Kapil G. Kapoor, MD and Sophie J. Bakri, MD
Chapter 6 Intravitreal Anti-Vascular Endothelial Growth Factor Therapy 
Mariana R. Thorell, MD and Philip J. Rosenfeld, MD, PhD
Chapter 7 Thermal Laser and Photodynamic Therapy 
Llewelyn J. Rao, MD and Lawrence J. Singerman, MD, FACS
Chapter 8 Treatment Failures: Nonresponders, Tolerance, and Tachyphylaxis 
Christopher J. Brady, MD and Chirag P. Shah, MD, MPH
Chapter 9 Surgery for Age-Related Macular Degeneration
Christopher J. Brady, MD and Carl D. Regillo, MD
Chapter 10 Future Therapies 
Roger A. Goldberg, MD, MBA and Jeffrey S. Heier, MD

Appendix 
Financial Disclosures 
Index