50 and More Essential NMR Experiments A Detailed Guide

This book is the perfect link for learning how to perform the experiments after only having studied theory. In eight chapters more than 50 essential NMR experiments are described in detail. Special focus is put on the organic set of NMR spectra (1H, 13C-APT, COSY, NOESY, HSQC and HMBC). Different chapters deal with advanced organic NMR, selective methods, heteronuclear NMR, relaxation and diffusion measurements, organic applications and maintenance. Every experiment has a section providing the reader with the purpose and scope of the specific experiment. Every experiment is concluded with the spectrum as it is obtained under the conditions described. Questions
and comments enable the reader to check their understanding. The authors are very experienced and the whole book is in full color, which enhances the reading experience and makes the spectra and other figures easier to understand.

This book is strongly recommended for all students and researchers who are involved in the structural elucidation of chemical compounds both in practical education and in pursuing research, in particular if they handle an NMR spectrometer.

Stefan Berger studied at the University of Tübingen (Germany), where he also received his PhD degree with Prof. Anton Rieker. He was a postdoctoral fellow with Prof. J. D. Roberts at California Institute of Technology (USA). He completed his habilitation in NMR spectroscopy at the University of Marburg (Germany). Since 1997 he is Professor of Structural Analysis at the University of Leipzig, where his research interests focus on methodological development of NMR and its application to bioorganic problems.

Dr. Matthias Findeisen is a researcher at the University of Leipzig, where he works together with Prof. Berger. He has extensive experience in NMR spectroscopy, including problem solving as well as technical and methodological developments.

THE ORGANIC SET OF NMR SPECTRA
1H NMR
APT-13C NMR [Attached Proton Test]
COSY [COrelation SpectroscopY]
NOESY [Nuclear Overhauser Effect SpectroscopY]
HSQC [Heteronuclear Single Quantum Coherence]
HMBC [Heteronuclear Multible Bond Correlation]
ADVANCED ORGANIC NMR SPECTROSCOPY
2D J-Resolved 1H NMR Spectroscopy
ROESY
TOCSY
HSQC-TOCSY
HOESY
INADEQUATE
ADEQUATE
J-HMBC
Gated
EXPERIMENTS FOR PHYSICAL ORGANIC CHEMISTRY
T1
T2
Dynamic NMR
DOSY
RDC
HETERONUCLEAR NMR
15N
17O
11B
19F
29Si
57Fe
195Pt
SELECTIVE METHODS
Presaturation
Sel.NOE
DPFGSE
WET
SelTOCSY
SELNOE
Selincor
Selinquate
ORGANIC CHEMISTRY APPLICATIONS
ASIS
Chirality determination
Advanced Mosher reagents
Quantitative NMR and Relaxation reagent
Determination of Association Constants Ka
Saturation Transfer Difference NMR
Quantitative 13C NMR Spectroscopy with Inverse Gated 1H-Decoupling
AN EXCURSION TO THE SOLID STATE AND TO STRUCTURAL BIOLOGY
CPMAS
HR/MAS
HNCA
HNCANNH
HNCCC
INSTRUMENT SETUP
Pulse determination
Pulse determination in the second channel
Selective Pulses
Adiabatic pulses
Radiation Damping
Temperature Calibration
Gradient calibration