Acanthamoeba: Biology and Pathogenesis

This book provides the first comprehensive review of Acanthamoeba research to be published. Everything that is known about Acanthamoeba is critically reviewed and divided into easy-to-follow sections. This book presents the current state of research on every aspect of this organism, detailing major advances in areas such as genomics, molecular and cellular biology, life cycles, geographical distribution, role in ecosystem, morphology, motility, phylogenetics, genotyping, metabolism, regulation of morphogenesis, host-parasite interactions, the molecular and immunological basis of pathogenesis, methods of transmission, epidemiology, clinical manifestation, diagnosis, treatment, new target development and drug resistance, as well as its role as a Trojan horse of the microbial world, including viral, bacterial, protozoal and fungal pathogens, and much more. There is a significant emphasis on our knowledge of Acanthamoeba infections that has grown in the molecular era. In addition, this book provides a historical perspective on Acanthamoeba research that will be of considerable interest. This compilation will serve as an essential reference for microbiologists, immunologists, and physicians in the field of basic and medical microbiology, as well as an invaluable reference for new and experienced researchers who wish to understand this organism better. This book is the definitive guide to current research on this increasingly important organism.

Dr. Naveed Ahmed Khan is an Associate Professor in Medical Microbiology at the University of Nottingham, UK. His research interests lie in the field of medical microbiology. Previously he worked at the Tufts University School of Medicine, Boston, and Johns Hopkins University School of Medicine, Baltimore, USA, as well as the University of London, UK. He has over 15 years of research experience with over 70 peer-reviewed publications and is the author of 3 books in the field of infectious diseases. Throughout these years, the focus of his research has remained Acanthamoeba, an intriguing pathogen with a fascinating biology.