Access to Experimental Drugs in Terminal

(Pharmaceutical Products Press) Univ. of Central Lancashire Centre for Professional Ethics, Preston, UK. Addresses the question: Are there good ethical reasons to prevent people with terminal illness such as AIDS from buying and using experimental drugs?

Preface

ix

Introduction

1

(8)

Autonomy---Access to Experimental Drugs and the Terminally III

9

(80)

Immanuel Kant

15

(9)

Weak Paternalism

24

(17)

John Stuart Mill

Weak Paternalism

41

(15)

Joel Feinberg

Weak Paternalism

56

(8)

Gerald Dworkin

Weak Paternalism

64

(10)

Tom L. Beauchamp

James F. Childress

Ruth R. Faden

Strong Paternalism

74

(7)

Robert Young

The Importance of Respecting Individual Autonomy

81

(4)

Summary of the Philosophical Debate

85

(2)

Practical Implications of the Arguments

87

(2)

Should We Restrict Access to Experimental Drugs to Promote Clinical Trials?

89

(56)

Research Clinical Trials---Are They Designed to Help Current or Future Patients?

97

(4)

Physicians and Patients

101

(6)

The Fischl/Richman AZT Trial

107

(14)

Ethical Analysis of the Fischl/Richman AZT Trial

121

(12)

Coercive Offers, or You Cannot Have It Both Ways

133

(5)

Placebos and Other Drugs

138

(2)

Summary

140

(5)

Costs and Other Practical Problems

145

(24)

Access to Experimental Drugs in Societies with Universal Health Care

151

(5)

Access to Experimental Drugs in Societies Without Universal Health Care

156

(5)

Provision of Information About Experimental Drugs

161

(6)

Practical Cultural Hindrances in Exercising Autonomy

167

(2)

Conclusion

169

(4)

Notes

173

(32)

Bibliography

205

(14)

Index

219

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Access to Experimental Drugs in Terminal Illness

Summary

Table of Contents

Supplemental Materials