Advances in Chromatographic Techniques for Therapeutic Drug Monitoring

For drugs with a narrow therapeutic index, therapeutic drug monitoring methods, such as immonassays and chromatographic techniques, are essential for patient management. Although immunoassays are available for determining serum or plasma concentrations, they often suffer from many limitations. Providing practical guidelines for implementing chromatographic methods, this comprehensive book describes the theory and application of therapeutic drug monitoring in clinical laboratories. It presents the theoretical framework and addresses commonly encountered problems in immunoassay methods. It also examines the interaction of herbal supplements with drugs being monitored.